Imperial College London

Emeritus ProfessorPeterTyrer

Faculty of MedicineDepartment of Brain Sciences

Emeritus Professor in Community Psychiatry - Clinical
 
 
 
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Contact

 

+44 (0)20 3313 4161p.tyrer

 
 
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Location

 

13.09Claybrook CentreCharing Cross Campus

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Summary

 

Publications

Publication Type
Year
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600 results found

Tyrer P, Horn S, Lee I, 1978, TREATMENT OF AGORAPHOBIA BY SUBLIMINAL AND SUPRALIMINAL EXPOSURE TO PHOBIC CINE FILM, The Lancet, Vol: 311, Pages: 358-360, ISSN: 0140-6736

Journal article

TYRER P, LEWIS P, LEE IAN, 1978, EFFECTS OF SUBLIMINAL AND SUPRALIMINAL STRESS ON SYMPTOMS OF ANXIETY, The Journal of Nervous and Mental Disease, Vol: 166, Pages: 88-95, ISSN: 0022-3018

Journal article

RUTHERFORD DM, OKOKO A, TYRER PJ, 1978, PLASMA CONCENTRATIONS OF DIAZEPAM AND DESMETHYLDIAZEPAM DURING CHRONIC DIAZEPAM THERAPY, BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, Vol: 6, Pages: 69-73, ISSN: 0306-5251

Journal article

Tyrer PJ, 1977, Delivery of postgraduate education., Br Med J, Vol: 1, ISSN: 0007-1447

Journal article

TYRER PJ, 1977, DELIVERY OF POSTGRADUATE EDUCATION, BRITISH MEDICAL JOURNAL, Vol: 1, Pages: 1661-1661, ISSN: 0959-8138

Journal article

TYRER PJ, 1977, PROPRANOLOL IN SCHIZOPHRENIA, LANCET, Vol: 2, Pages: 761-761, ISSN: 0140-6736

Journal article

TYRER PJ, 1976, SCREENING PROCEDURES IN VOLUNTEERS AND PATIENTS, BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, Vol: 3, Pages: 35-40, ISSN: 0306-5251

Journal article

TYRER PJ, LADER MH, 1976, CENTRAL AND PERIPHERAL CORRELATES OF ANXIETY - COMPARATIVE STUDY, JOURNAL OF NERVOUS AND MENTAL DISEASE, Vol: 162, Pages: 99-104, ISSN: 0022-3018

Journal article

Tyrer P, 1975, A Practical Classification of Morbid Anxiety, Scottish Medical Journal, Vol: 20, Pages: 283-284, ISSN: 0036-9330

Journal article

Tyrer P, Steinberg D, 1975, Symptomatic Treatment of Agoraphobia and Social Phobias: A Follow-up Study, British Journal of Psychiatry, Vol: 127, Pages: 163-168, ISSN: 0007-1250

<jats:title>Summary</jats:title><jats:p><jats:list list-type="number"><jats:list-item><jats:label>1.</jats:label><jats:p>Twenty-six out of 28 out-patients with agoraphobia and social phobias who had originally been treated with phenelzine or placebo in a double-blind clinical trial were followed up for a mean period of one year. During the follow-up period patients received further pharmacotherapy or behaviour therapy, except that those patients originally receiving placebo were not allowed therapy with monoamine oxidase inhibitors.</jats:p></jats:list-item><jats:list-item><jats:label>2.</jats:label><jats:p>Ratings of phobic and additional symptoms, social adjustment and degree of personality disorder were made after one year by one of the authors (D.S.) who had no prior knowledge of the treatment each patient had received.</jats:p></jats:list-item><jats:list-item><jats:label>3.</jats:label><jats:p>There were no significant differences in any of the ratings between the patients of the two groups, but those originally receiving placebo had more additional treatment in the follow-up period. Patients continuing to receive phenelzine frequently experienced a return of symptoms if the drug was withdrawn before six months treatment had elapsed.</jats:p></jats:list-item><jats:list-item><jats:label>4.</jats:label><jats:p>Degree of personality disorder showed a significant negative correlation (p = –0.6) with improvement in the phenelzine group but not in those receiving placebo originally.</jats:p></jats:list-item><jats:list-item><jats:label>5.</jats:label><jats:p>Improvement in social adjustment items was less than improvement in symptoms at follow-up. The implications of this are discussed.</jats:p></jats:list-item><jats:list-item><jats:label>6

Journal article

Tyrer PJ, Tyrer PJ, 1975, Letter: Working to a new contract?, Lancet, Vol: 1, ISSN: 0140-6736

Journal article

TYRER PJ, 1975, WORKING TO A NEW CONTRACT, LANCET, Vol: 1, Pages: 796-796, ISSN: 0140-6736

Journal article

TYRER PJ, 1975, BENZODIAZEPINES IN CLINICAL PRACTICE - GREENBLATT,DJ AND SHADER,RI, JOURNAL OF PSYCHOSOMATIC RESEARCH, Vol: 19, Pages: 162-162, ISSN: 0022-3999

Journal article

TYRER PJ, KASRIEL J, 1975, GENETIC COMPONENTS OF PHYSIOLOGICAL TREMOR, JOURNAL OF MEDICAL GENETICS, Vol: 12, Pages: 162-164, ISSN: 0022-2593

Journal article

Tyrer P, Tyrer S, 1974, School refusal, truancy, and adult neurotic illness, Psychological Medicine, Vol: 4, Pages: 416-421, ISSN: 0033-2917

<jats:title>SYSNOPSIS</jats:title><jats:p>Two hundred and forty adult psychiatric patients, comprising 60 phobic, 60 anxious, and 120 depressed patients, were interviewed about problems of school attendance during their childhood. Using a specially designed questionnaire, non-attendance due to school refusal was swparated from that due to truancy. A control population of 120 orthopaedic and dental patients, matched for age and sex with the psychiatric sample, was also interviewed. It was found that school refusal had occurred significantly more often among the psychiatric patients than among the controls (P &lt; 0·05). The incidence of truancy was similar in both groups. Both school refusal and truancy had occurred more frequently in female than in male patients. The results suggest that, contrary to some studies, there is a link between childhood and adult neurotic disorders and that some children who present with problems of school refusal are at risk in adult life.</jats:p>

Journal article

TYRER PJ, LADER MH, 1974, PHYSIOLOGICAL-RESPONSE TO PROPRANOLOL AND DIAZEPAM IN CHRONIC ANXIETY, BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, Vol: 1, Pages: 387-390, ISSN: 0306-5251

Journal article

TYRER PJ, LADER MH, 1974, PHYSIOLOGICAL AND PSYCHOLOGICAL EFFECTS OF +/-PROPRANOLOL, +-PROPRANOLOL AND DIAZEPAM IN INDUCED ANXIETY, BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, Vol: 1, Pages: 379-385, ISSN: 0306-5251

Journal article

TYRER PJ, LADER MH, 1974, TREMOR IN ACUTE AND CHRONIC ANXIETY, ARCHIVES OF GENERAL PSYCHIATRY, Vol: 31, Pages: 506-509, ISSN: 0003-990X

Journal article

TYRER PJ, BOND AJ, 1974, DIURNAL-VARIATION IN PHYSIOLOGICAL TREMOR, ELECTROENCEPHALOGRAPHY AND CLINICAL NEUROPHYSIOLOGY, Vol: 37, Pages: 35-40, ISSN: 0013-4694

Journal article

TYRER PJ, LADER MH, 1974, RESPONSE TO PROPRANOLOL AND DIAZEPAM IN SOMATIC AND PSYCHIC ANXIETY, BMJ-BRITISH MEDICAL JOURNAL, Vol: 2, Pages: 14-16, ISSN: 1756-1833

Journal article

Rea JN, Tyrer PJ, Kasap HS, Beresford SAet al., 1973, Expired air carbon monoxide, smoking, and other variables. A community study., Br J Prev Soc Med, Vol: 27, Pages: 114-120, ISSN: 0007-1242

Journal article

Tyrer P, Candy J, Kelly D, 1973, Phenelzine in phobic anxiety: a controlled trial, Psychological Medicine, Vol: 3, Pages: 120-124, ISSN: 0033-2917

<jats:title>Synopsis</jats:title><jats:p>A double-blind trial of phenelzine versus placebo in psychiatric outpatients with long-standing phobic anxiety is described. Forty patients with agoraphobia or social phobias entered the trial and 32 of these completed treatment with either phenelzine or placebo (with appropriate dietary restrictions) in flexible dosage for two months. Fourteen pairs of patients were prospectively matched, and analysis of the score differences between these pairs showed a significant improvement for patients on phenelzine compared with placebo on overall assessment (P&lt;0·01) and secondary phobias (P&lt;0·05). These differences were not shown at assessment after one month's treatment, but became marked after two months. The improvement on phenelzine, which was maintained at follow-up, was not related to initial depressive symptoms in the patients. It is suggested that phenelzine is an effective agent in the treatment of phobic anxiety but that treatment needs to be continued for at least two months before full benefit is achieved.</jats:p>

Journal article

TYRER PJ, 1973, RELEVANCE OF BODILY FEELINGS IN EMOTION, LANCET, Vol: 1, Pages: 915-916, ISSN: 0140-6736

Journal article

TYRER PJ, 1973, HISTORY OF BRITISH PSYCHOANALYSIS, BRITISH JOURNAL OF PSYCHIATRY, Vol: 122, Pages: 367-367, ISSN: 0007-1250

Journal article

TYRER PJ, LADER MH, 1973, EFFECTS OF BETA-ADRENERGIC BLOCKADE WITH SOTALOL IN CHRONIC ANXIETY, CLINICAL PHARMACOLOGY & THERAPEUTICS, Vol: 14, Pages: 418-426, ISSN: 0009-9236

Journal article

REA JN, TYRER PJ, KASAP HS, BERESFORD SAet al., 1973, EXPIRED AIR CARBON-MONOXIDE, SMOKING, AND OTHER VARIABLES, BRITISH JOURNAL OF PREVENTIVE & SOCIAL MEDICINE, Vol: 27, Pages: 114-120, ISSN: 0007-1242

Journal article

Tyrer P, Candy J, Kelly D, 1973, A study of the clinical effects of phenelzine and placebo in the treatment of phobic anxiety, Psychopharmacologia, Vol: 32, Pages: 237-254, ISSN: 0033-3158

Journal article

Lader MH, Tyrer PJ, 1972, Central and peripheral effects of propranolol and sotalol in normal human subjects., Br J Pharmacol, Vol: 45, Pages: 557-560, ISSN: 0007-1188

No unequivocal central effects were found with either +/--propranolol (120 mg) or +/--sotalol (240 mg) in acute dosage in normal subjects. Subjective feelings of drowsiness and muzziness were found with sotalol and both sotalol and propranolol caused subjects to feel more troubled. These changes were not accompanied by physiological or behavioural evidence of sedation. Adequate beta-adrenoceptor blockade was achieved as measured by a significant fall in pulse-rate on both active drugs but no other significant peripheral physiological changes occurred.

Journal article

LADER MH, TYRER PJ, 1972, CENTRAL AND PERIPHERAL EFFECTS OF PROPRANOLOL AND SOTALOL IN NORMAL HUMAN SUBJECTS, BRITISH JOURNAL OF PHARMACOLOGY, Vol: 45, Pages: 557-&, ISSN: 0007-1188

Journal article

TYRER PJ, LADER MH, 1972, SOME CLINICAL AND PHYSIOLOGICAL EFFECTS OF SOTALOL IN CHRONIC ANXIETY, PSYCHOPHARMACOLOGIA, Vol: 26, Pages: 50-&

Journal article

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