Publications
656 results found
Tyrer P, Casey P, Gall J, 1983, the relationship between neurosis and personality disorder, British Journal of psychiatry
Tyrer PJ, 1982, The concept of somatic anxiety., Br J Psychiatry, Vol: 140, ISSN: 0007-1250
TYRER PJ, 1982, THE CONCEPT OF SOMATIC ANXIETY, BRITISH JOURNAL OF PSYCHIATRY, Vol: 140, Pages: 325-325, ISSN: 0007-1250
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- Citations: 8
TYRER PJ, 1982, ANXIETY - REPLY, BRITISH JOURNAL OF HOSPITAL MEDICINE, Vol: 27, Pages: 694-694, ISSN: 0007-1064
Tyrer P, Huggettt T, 1981, Benzodiazepine withdrawal symptoms and propranolol, Lancet
GRIGGS S, TYRER PJ, 1981, PERSONALITY-DISORDER, SOCIAL-ADJUSTMENT AND TREATMENT OUTCOME IN ALCOHOLICS, JOURNAL OF STUDIES ON ALCOHOL, Vol: 42, Pages: 802-805, ISSN: 0096-882X
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- Citations: 27
Tyrer P, 1980, Dependence on Benzodiazepines, British Journal of Psychiatry, Vol: 137, Pages: 576-577, ISSN: 0007-1250
Tyrer P, Gardner M, Lambourn J, et al., 1980, Clinical and Pharmacokinetic Factors Affecting Response to Phenelzine, British Journal of Psychiatry, Vol: 136, Pages: 359-365, ISSN: 0007-1250
<jats:title>Summary</jats:title><jats:p>Sixty patients, 30 with depressive neurosis, 15 with anxiety neurosis and 15 with phobic anxiety states, were treated with the monoamine oxidase inhibitor, phenelzine, in two different dosage schedules for four weeks. All patients received an initial dose of 15 mg daily, increasing to 30 mg daily between the third and seventh day, but subsequently, using double-blind procedure, one group took the commonly prescribed dose of 45 mg daily and the other took 90 mg daily. Acetylator status was independently determined before the start of treatment. Each diagnostic group showed a similar response to treatment, but patients taking the higher dose improved significantly more than those taking normal dosage, and the rate of improvement, measured by weekly self-ratings, was also more rapid with higher dosage. Acetylator status did not affect clinical response. The results suggest that dosage is more important in determining clinical response to phenelzine in neurotic disorder than specific diagnosis or acetylator status.</jats:p>
Tyrer P, Lee I, Alexander J, 1980, Awareness of cardiac function in anxious, phobic and hypochondriacal patients, Psychological Medicine, Vol: 10, Pages: 171-174, ISSN: 0033-2917
<jats:title>SYNOPSIS</jats:title><jats:p>Awareness of pulse rate was tested in 60 psychiatric out-patients with anxiety, phobic or hypochondriacal neuroses by asking them to record how fast their hearts were beating during exposure to short film sequences. Correlations between subjective and objective heart rate (ECG) were significantly higher in anxious and hypochondriacal patients than in phobic ones. The results suggest that somatic symptoms in hypochondriacal and anxiety neurosis reflect increased awareness of bodily function.</jats:p>
Tyrer P, Alexander MS, Regan A, et al., 1980, An Extrapyramidal Syndrome after Lithium Therapy, British Journal of Psychiatry, Vol: 136, Pages: 191-194, ISSN: 0007-1250
<jats:title>Summary</jats:title><jats:p>Two patients developed an extrapyramidal syndrome after therapy with lithium carbonate. Although the clinical features of this syndrome were indistinguishable from those of drug-induced parkinsonism, it was made worse by the anti-parkinsonian drug, orphenadrine. These findings were reproduced later under laboratory conditions when extrapyramidal symptoms and physiological tremor were recorded before and after challenge doses of orphenadrine. This unwanted effect of lithium carbonate may be explained by selective blockade of dopamine receptors.</jats:p>
Tyrer PJ, 1980, Combined antidepressant treatment., Br Med J, Vol: 280, ISSN: 0007-1447
TYRER PJ, 1980, COMBINED ANTI-DEPRESSANT TREATMENT, BRITISH MEDICAL JOURNAL, Vol: 280, Pages: 183-183, ISSN: 0959-8138
SMITH SE, LAMBOURN J, TYRER PJ, 1980, ANTIPYRINE ELIMINATION BY PATIENTS UNDER TREATMENT WITH MONOAMINE-OXIDASE INHIBITORS, BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, Vol: 9, Pages: 21-25, ISSN: 0306-5251
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- Citations: 7
TYRER PJ, LEE I, EDWARDS JG, et al., 1980, PROGNOSTIC FACTORS DETERMINING RESPONSE TO ANTI-DEPRESSANT DRUGS IN PSYCHIATRIC OUT-PATIENTS AND GENERAL-PRACTICE, JOURNAL OF AFFECTIVE DISORDERS, Vol: 2, Pages: 149-156, ISSN: 0165-0327
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- Citations: 17
TYRER PJ, 1980, AUTONOMIC NERVOUS-SYSTEM - PHYSIOLOGICAL-BASIS OF PSYCHOSOMATIC THERAPY, BRITISH JOURNAL OF PSYCHIATRY, Vol: 136, Pages: 95-96, ISSN: 0007-1250
TYRER PJ, 1980, CENTRAL NERVOUS-SYSTEM PHARMACOLOGY - SELF-INSTRUCTION TEXT, 2ND EDITION, BRITISH JOURNAL OF PSYCHIATRY, Vol: 136, Pages: 95-96, ISSN: 0007-1250
TYRER PJ, 1980, HISTORY OF PENICILLIN, LANCET, Vol: 1, Pages: 44-44, ISSN: 0140-6736
TYRER PJ, 1980, USE OF BETA-BLOCKING DRUGS IN PSYCHIATRY AND NEUROLOGY, DRUGS, Vol: 20, Pages: 300-308, ISSN: 0012-6667
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- Citations: 43
Tyrer P, Alexander J, 1979, Classification of Personality Disorder, British Journal of Psychiatry, Vol: 135, Pages: 163-167, ISSN: 0007-1250
<jats:title>Summary</jats:title><jats:p>An interview schedule was used to record the personality traits of 130 psychiatric patients, 65 with a primary clinical diagnosis of personality disorder and 65 with other diagnoses. The results were analysed by factor analysis and three types of cluster analysis. Factor analysis showed a similar structure of personality variables in both groups of patients, supporting the notion that personality disorders differ only in degree from the personalities of other psychiatric patients. Cluster analysis revealed five discrete categories; sociopathic, passive-dependent, anankastic, schizoid and a non-personality-disordered group. Of all the personality-disordered patients 63 per cent fell into the passive-dependent or sociopathic category. The results suggest that the current classification of personality disorder could be simplified.</jats:p>
Tyrer P, Alexander MS, Cicchetti D, et al., 1979, Reliability of a Schedule for Rating Personality Disorders, British Journal of Psychiatry, Vol: 135, Pages: 168-174, ISSN: 0007-1250
<jats:title>Summary</jats:title><jats:p>The inter-situational, inter-rater and temporal reliability of a schedule for rating personality disorders is described. In an initial study with a simplified form of the schedule in patients from different wards of a psychiatric hospital inter-situational reliability between raters was higher for patients with personality disorders than with no personality disorder. Using the full schedule, inter-rater reliability, using audiotaped and separate interviews, and temporal reliability at interviews conducted a mean of 12.5 months apart all reached a satisfactory level, suggesting that the schedule may be a useful instrument for measuring deviant personality traits. The interview may be used with a subject or an informant but agreement between ratings made with informants and psychiatric patients during illness was low, and the schedule is not recommended for use with patients alone during acute episodes of illness.</jats:p>
REMINGTON M, TYRER PJ, NEWSONSMITH J, et al., 1979, COMPARATIVE RELIABILITY OF CATEGORICAL AND ANALOG RATING-SCALES IN THE ASSESSMENT OF PSYCHIATRIC SYMPTOMATOLOGY, PSYCHOLOGICAL MEDICINE, Vol: 9, Pages: 765-770, ISSN: 0033-2917
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- Citations: 44
Remington M, Tyrer P, 1979, The social functioning schedule ? A brief semi-structured interview, Social Psychiatry, Vol: 14, Pages: 151-157, ISSN: 0037-7813
TYRER PJ, REMINGTON M, 1979, CONTROLLED COMPARISON OF DAY-HOSPITAL AND OUTPATIENT TREATMENT FOR NEUROTIC DISORDERS, LANCET, Vol: 1, Pages: 1014-1016, ISSN: 0140-6736
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- Citations: 37
Tyrer P, 1978, Drug treatment of psychiatric patients in general practice., BMJ, Vol: 2, Pages: 1433-1434, ISSN: 0959-8138
Tyrer P, Horn S, Lee I, 1978, TREATMENT OF AGORAPHOBIA BY SUBLIMINAL AND SUPRALIMINAL EXPOSURE TO PHOBIC CINE FILM, The Lancet, Vol: 311, Pages: 358-360, ISSN: 0140-6736
TYRER P, LEWIS P, LEE IAN, 1978, EFFECTS OF SUBLIMINAL AND SUPRALIMINAL STRESS ON SYMPTOMS OF ANXIETY, The Journal of Nervous and Mental Disease, Vol: 166, Pages: 88-95, ISSN: 0022-3018
RUTHERFORD DM, OKOKO A, TYRER PJ, 1978, PLASMA CONCENTRATIONS OF DIAZEPAM AND DESMETHYLDIAZEPAM DURING CHRONIC DIAZEPAM THERAPY, BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, Vol: 6, Pages: 69-73, ISSN: 0306-5251
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- Citations: 36
Tyrer PJ, 1977, Delivery of postgraduate education., Br Med J, Vol: 1, ISSN: 0007-1447
TYRER PJ, 1977, DELIVERY OF POSTGRADUATE EDUCATION, BRITISH MEDICAL JOURNAL, Vol: 1, Pages: 1661-1661, ISSN: 0959-8138
TYRER PJ, 1977, PROPRANOLOL IN SCHIZOPHRENIA, LANCET, Vol: 2, Pages: 761-761, ISSN: 0140-6736
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- Citations: 6
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