Summary
Dr Ulug completed her BSc in Biological Sciences with French at the University of Rochester, New York in 2003 as a Fulbright/ CASP (Cyprus-America Scholarship Program) Scholar and subsequently an MSc in Molecular Biology at the University of Wales, Cardiff. She then completed her PhD in Molecular Haematology at King’s College London, with the support of an MRC-funded studentship at Professor Swee Lay Thein’s laboratory, investigating potential markers of disease severity in patients with sickle cell disease. After working as a Postdoctoral Researcher at Queen Mary, University of London, she joined the Vascular Surgery Research Group at Imperial College London in 2009 as Clinical Trial Manager and coordinated and managed the IMPROVE trial (multi-centre, emergency surgery randomised controlled trial supported by the NIHR HTA programme), which reported final results in 2017. Dr Ulug has also worked on a project involving individual patient data meta-analysis of EVAR-1, DREAM, OVER and ACE randomised controlled trials that compared elective endovascular and open repair of abdominal aortic aneurysm (a very large pool of world first randomised data from four countries). She has experience of working with Hospital Episode Statistics (HES) data extracts, in particular cleaning the data to improve validity. Most recently, Dr Ulug worked in collaboration with specialists in vascular surgery, AAA epidemiology, medical statistics and health economics, from the Universities of Cambridge, Leicester and Brunel on another UK Department of Health funded project to assess the feasibility of population screening in women, which reported results in 2018.
Since 2019, Dr Ulug has been working on the British Society of Endovascular Therapy -ConformabLe EndoVascular Aneurysm Repair (BSET-CLEVAR) Registry, which involves 19 NHS hospitals in the UK.
recent awards:
Frank Lederle Prize at the 6th International Meeting on Aortic Diseases (2018) for best short communication on epidemiology and natural history of abdominal aortic aneurysm (Abstract title: "Should we screen women for abdominal aortic aneurysm?").
Raymond Limet Special Prize at International Meeting on Aortic Diseases (IMAD) 2016 for the presentation of “Meta-analysis of the current prevalence of screen-detected abdominal aortic aneurysm in women”.
Selected Publications
Journal Articles
Ulug P, Powell JT, 2020, Clinical trial reporting, The Lancet, Vol:396, ISSN:0140-6736, Pages:1489-1489
Ulug P, Powell JT, Martinez MA-M, et al., 2020, Surgery for small asymptomatic abdominal aortic aneurysms., Cochrane Database of Systematic Reviews, Vol:7, ISSN:1469-493X, Pages:CD001835-CD001835
Ulug P, Powell J, Warschkow R, et al., 2019, Editor's Choice – Sex Specific Differences in the Management of Descending Thoracic Aortic Aneurysms: Systematic Review with Meta-Analysis, European Journal of Vascular and Endovascular Surgery, Vol:58, ISSN:1078-5884, Pages:503-511
Grootes I, Barrett JK, Ulug P, et al., 2018, Predicting risk of rupture and rupture-preventing re-interventions utilising repeated measures on aneurysm sac diameter following endovascular abdominal aortic aneurysm repair, British Journal of Surgery, Vol:105, ISSN:1365-2168, Pages:1294-1304
Sweeting MJ, Masconi KL, Jones E, et al., 2018, Analysis of clinical benefit, harms, and cost-effectiveness of screening women for abdominal aortic aneurysm., Lancet, Vol:392, Pages:487-495
Sweeting MJ, Ulug P, Roy J, et al., 2018, Value of risk scores in the decision to palliate patients with ruptured abdominal aortic aneurysm, British Journal of Surgery, Vol:105, ISSN:0007-1323, Pages:1135-1144
Powell JT, Sweeting MJ, Ulug P, et al., 2018, Re-interventions after repair of ruptured abdominal aortic aneurysm: a report from the IMPROVE randomised trial, European Journal of Vascular and Endovascular Surgery, Vol:55, ISSN:1078-5884, Pages:625-632
Powell JT, IMPROVE Trail Investigators, 2017, Comparative clinical effectiveness and cost-effectiveness of an endovascular strategy versus open repair for ruptured abdomina aortic aneurysm: 3-year results of the IMPROVE randomised trial, British Medical Journal, Vol:359, ISSN:0959-8138
Mason AJ, Gomes M, Grieve R, et al., 2017, Development of a practical approach to expert elicitation for randomised controlled trials with missing health outcomes: Application to the IMPROVE trial, Clinical Trials, Vol:14, ISSN:1740-7745, Pages:357-367
Ulug P, Sweeting MJ, von Allmen RS, et al., 2017, Morphological suitability for endovascular repair, non-intervention rates, and operative mortality in women and men assessed for intact abdominal aortic aneurysm repair: systematic reviews with meta-analysis, The Lancet, Vol:389, ISSN:0140-6736, Pages:2482-2491
Powell JT, Sweeting MJ, Ulug P, et al., 2017, Meta-analysis of individual-patient data from EVAR-1, DREAM, OVER and ACE trials comparing outcomes of endovascular or open repair for abdominal aortic aneurysm over 5 years, British Journal of Surgery, Vol:104, ISSN:1365-2168, Pages:166-178
Ulug P, Powell J, Sweeting MJ, et al., 2016, Meta-analysis of the current prevalence of screen-detected abdominal aortic aneurysm in women, British Journal of Surgery, Vol:103, ISSN:1365-2168, Pages:1097-1104
Powell JT, Ulug P, 2015, PATIENTS AND TRIAL ENROLMENT DECISIONS Flexibility in trial enrolment decisions, British Medical Journal, Vol:351, ISSN:1756-1833
Sweeting MJ, Balm R, Desgranges P, et al., 2015, Individual-patient meta-analysis of three randomized trials comparing endovascular versus open repair for ruptured abdominal aortic aneurysm, British Journal of Surgery, Vol:102, ISSN:1365-2168, Pages:1229-1239
Sweeting MJ, Ulug P, Powell JT, et al., 2015, Ruptured aneurysm trials: The importance of longer-term outcomes and meta-analysis for 1-year mortality., European Journal of Vascular and Endovascular Surgery, Vol:50, ISSN:1532-2165, Pages:297-302
Grieve R, Gomes M, Sweeting MJ, et al., 2015, Endovascular strategy or open repair for ruptured abdominal aortic aneurysm: one-year outcomes from the IMPROVE randomized trial, European Heart Journal, Vol:36, ISSN:1522-9645, Pages:2061-2069
Powell JT, Sweeting MJ, Thompson MM, et al., 2015, The effect of aortic morphology on peri-operative mortality of ruptured abdominal aortic aneurysm, European Heart Journal, Vol:36, ISSN:1522-9645, Pages:1328-U137
Powell JT, Hinchliffe RJ, Thompson MM, et al., 2014, An Endovascular Strategy for Suspected Ruptured Abdominal Aortic Aneurysm Brings Earlier Home Discharge but Not Early Survival or Cost Benefits, European Journal of Vascular and Endovascular Surgery, Vol:47, ISSN:1078-5884, Pages:333-334
Powell JT, Hinchliffe RJ, Thompson MM, et al., 2014, Observations from the IMPROVE trial concerning the clinical care of patients with ruptured abdominal aortic aneurysm, British Journal of Surgery, Vol:101, ISSN:1365-2168, Pages:216-224
Powell JT, Sweeting MJ, Thompson MM, et al., 2014, Endovascular or open repair strategy for ruptured abdominal aortic aneurysm: 30 day outcomes from IMPROVE randomised trial, British Medical Journal, Vol:348, ISSN:1468-5833, Pages:1-12
Hinchliffe RJ, Ribbons T, Ulug P, et al., 2013, Transfer of patients with ruptured abdominal aortic aneurysm from general hospitals to specialist vascular centres: results of a Delphi consensus study, Emergency Medicine Journal, Vol:30, ISSN:1472-0205, Pages:483-486
Ulug P, McCaslin JE, Stansby G, et al., 2012, Endovascular versus conventional medical treatment for uncomplicated chronic type B aortic dissection, Cochrane Database of Systematic Reviews, ISSN:1469-493X
Powell JT, Thompson MM, Thompson SG, et al., 2010, Getting research in the NHS started, The Lancet, Vol:375, ISSN:0140-6736, Pages:2072-2072