Imperial College London
Alternate

DrPinarUlug

Faculty of Medicine, Department of Surgery & Cancer

Honorary Research Fellow
 
 
 
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Contact

 

+44 (0)20 3311 7307p.ulug Website

 
 
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Location

 

North Wing - 4N12Charing Cross HospitalCharing Cross Campus

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Summary

 

Publications

Citation

BibTex format

@article{Ulug:2020:10.1002/14651858.CD001835.pub5,
author = {Ulug, P and Powell, JT and Martinez, MA-M and Ballard, DJ and Filardo, G},
doi = {10.1002/14651858.CD001835.pub5},
journal = {Cochrane Database of Systematic Reviews},
pages = {CD001835--CD001835},
title = {Surgery for small asymptomatic abdominal aortic aneurysms.},
url = {http://dx.doi.org/10.1002/14651858.CD001835.pub5},
volume = {7},
year = {2020}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - BACKGROUND: An abdominal aortic aneurysm (AAA) is an abnormal ballooning of the major abdominal artery. Some AAAs present as emergencies and require surgery; others remain asymptomatic. Treatment of asymptomatic AAAs depends on many factors, but the size of the aneurysm is important, as risk of rupture increases with aneurysm size. Large asymptomatic AAAs (greater than 5.5 cm in diameter) are usually repaired surgically; very small AAAs (less than 4.0 cm diameter) are monitored with ultrasonography. Debate continues over the roles of early repair versus surveillance with repair on subsequent enlargement in people with asymptomatic AAAs of 4.0 cm to 5.5 cm diameter. This is the fourth update of the review first published in 1999. OBJECTIVES: To compare mortality and costs, as well as quality of life and aneurysm rupture as secondary outcomes, following early surgical repair versus routine ultrasound surveillance in people with asymptomatic AAAs between 4.0 cm and 5.5 cm in diameter. SEARCH METHODS: The Cochrane Vascular Information Specialist searched the Cochrane Vascular Specialised Register, CENTRAL, MEDLINE, two other databases, and two trials registers to 10 July 2019. We handsearched conference proceedings and checked reference lists of relevant studies. SELECTION CRITERIA: We included randomised controlled trials where people with asymptomatic AAAs of 4.0 cm to 5.5 cm were randomly allocated to early repair or imaging-based surveillance at least every six months. Outcomes had to include mortality or survival. DATA COLLECTION AND ANALYSIS: Three review authors independently extracted data, which were cross-checked by other team members. Outcomes were mortality, costs, quality of life, and aneurysm rupture. For mortality, we estimated risk ratios (RR) (endovascular aneurysm repair only), hazard ratios (HR) (open repair only), and 95% confidence intervals (CI) based on Mantel-Haenszel Chi2 statistics at one and six years (open repair only) following randomisation
AU  - Ulug,P
AU  - Powell,JT
AU  - Martinez,MA-M
AU  - Ballard,DJ
AU  - Filardo,G
DO  - 10.1002/14651858.CD001835.pub5
EP  - 001835
PY  - 2020///
SN  - 1469-493X
SP  - 001835
TI  - Surgery for small asymptomatic abdominal aortic aneurysms.
T2  - Cochrane Database of Systematic Reviews
UR  - http://dx.doi.org/10.1002/14651858.CD001835.pub5
UR  - https://www.ncbi.nlm.nih.gov/pubmed/32609382
UR  - https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD001835.pub5
UR  - http://hdl.handle.net/10044/1/80694
VL  - 7
ER  -
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