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@article{Vorkas:2018:10.4155/bio-2017-0249,
author = {Vorkas, PA},
doi = {10.4155/bio-2017-0249},
journal = {Bioanalysis},
pages = {307--319},
title = {Expanding lipidome coverage using MS/MS-aided untargeted data-independent RP-UPLC-TOF-MSE acquisition},
url = {http://dx.doi.org/10.4155/bio-2017-0249},
volume = {10},
year = {2018}
}

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TY  - JOUR
AB  - Lipid function and importance in disease are being rediscovered due to modern advancements in chemicalanalysis. RP–UPLC–TOF–MSE is now the lipidomics tool of choice and can provide the demanded specificityfor detecting the great diversity of the lipidome. It can offer simplicity, rapidity, robustness and highthroughputness, without the need for further optimization in current sample preparation protocols. Thismethod can cover the major lipid categories with the ability to detect several corresponding subclasses.It can deliver adequate information for deciphering fatty chain length, unsaturation and regioisomerism.It has enabled the detection of a vast number of lipids, of which more than 250 are reported here. Theselipids were detected from applications in a variety of biological matrices and species.
AU  - Vorkas,PA
DO  - 10.4155/bio-2017-0249
EP  - 319
PY  - 2018///
SN  - 1757-6180
SP  - 307
TI  - Expanding lipidome coverage using MS/MS-aided untargeted data-independent RP-UPLC-TOF-MSE acquisition
T2  - Bioanalysis
UR  - http://dx.doi.org/10.4155/bio-2017-0249
UR  - http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000427448100005&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
UR  - http://hdl.handle.net/10044/1/58255
VL  - 10
ER  -

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