Publications

BibTex format

@article{Gallo:2016:10.1007/s10654-016-0119-9,
author = {Gallo, V and Vanacore, N and Bueno-de-Mesquita, HB and Vermeulen, R and Brayne, C and Pearce, N and Wark, PA and Ward, HA and Ferrari, P and Jenab, M and Andersen, PM and Wennberg, P and Wareham, N and Katzke, V and Kaaks, R and Weiderpass, E and Peeters, PH and Mattiello, A and Pala, V and Barricante, A and Chirlaque, M-D and Travier, N and Travis, RC and Sanchez, M-J and Pessah-Rasmussen, H and Petersson, J and Tjonneland, A and Tumino, R and Ramon, Quiros J and Trichopoulou, A and Kyrozis, A and Oikonomidou, D and Masala, G and Sacerdote, C and Arriola, L and Boeing, H and Vigl, M and Claver-Chapelon, F and Middleton, L and Riboli, E and Vineis, P},
doi = {10.1007/s10654-016-0119-9},
journal = {European Journal of Epidemiology},
pages = {255--266},
title = {Physical activity and risk of Amyotrophic Lateral Sclerosis in a prospective cohort study},
url = {http://dx.doi.org/10.1007/s10654-016-0119-9},
volume = {31},
year = {2016}
}

Download

RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Previous case–control studies have suggested a possible increased risk of Amyotrophic Lateral Sclerosis (ALS) with physical activity (PA), but this association has never been studied in prospective cohort studies. We therefore assessed the association between PA and risk of death from ALS in the European Prospective Investigation into Cancer and Nutrition. A total of 472,100 individuals were included in the analysis, yielding 219 ALS deaths. At recruitment, information on PA was collected thorough standardised questionnaires. Total PA was expressed by the Cambridge Physical Activity Index (CPAI) and analysed in relation to ALS mortality, using Cox hazard models. Interactions with age, sex, and anthropometric measures were assessed. Total PA was weakly inversely associated with ALS mortality with a borderline statistically significant trend across categories (p = 0.042), with those physically active being 33 % less likely to die from ALS compared to those inactive: HR = 0.67 (95 % CI 0.42–1.06). Anthropometric measures, sex, and age did not modify the association with CPAI. The present study shows a slightly decreased—not increased like in case–control studies—risk of dying from ALS in those with high levels of total PA at enrolment. This association does not appear confounded by age, gender, anthropometry, smoking, and education. Ours was the first prospective cohort study on ALS and physical activity.
AU  - Gallo,V
AU  - Vanacore,N
AU  - Bueno-de-Mesquita,HB
AU  - Vermeulen,R
AU  - Brayne,C
AU  - Pearce,N
AU  - Wark,PA
AU  - Ward,HA
AU  - Ferrari,P
AU  - Jenab,M
AU  - Andersen,PM
AU  - Wennberg,P
AU  - Wareham,N
AU  - Katzke,V
AU  - Kaaks,R
AU  - Weiderpass,E
AU  - Peeters,PH
AU  - Mattiello,A
AU  - Pala,V
AU  - Barricante,A
AU  - Chirlaque,M-D
AU  - Travier,N
AU  - Travis,RC
AU  - Sanchez,M-J
AU  - Pessah-Rasmussen,H
AU  - Petersson,J
AU  - Tjonneland,A
AU  - Tumino,R
AU  - Ramon,Quiros J
AU  - Trichopoulou,A
AU  - Kyrozis,A
AU  - Oikonomidou,D
AU  - Masala,G
AU  - Sacerdote,C
AU  - Arriola,L
AU  - Boeing,H
AU  - Vigl,M
AU  - Claver-Chapelon,F
AU  - Middleton,L
AU  - Riboli,E
AU  - Vineis,P
DO  - 10.1007/s10654-016-0119-9
EP  - 266
PY  - 2016///
SN  - 1573-7284
SP  - 255
TI  - Physical activity and risk of Amyotrophic Lateral Sclerosis in a prospective cohort study
T2  - European Journal of Epidemiology
UR  - http://dx.doi.org/10.1007/s10654-016-0119-9
UR  - http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000373642000005&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
UR  - http://hdl.handle.net/10044/1/32245
VL  - 31
ER  -

Download

DrPetraWark

Contact

Location

Summary

Citation

BibTex format

RIS format (EndNote, RefMan)