Publications

BibTex format

@article{Molina-Montes:2017:10.1038/bjc.2017.14,
author = {Molina-Montes, E and Sánchez, M and Buckland, G and Bueno-de-Mesquita, B and Weiderpass, E and Amiano, P and Wark, PA and Kuhn, T and Katzke, V and Huerta, JM and Ardanaz, E and Ramón, Quirós J and Affret, A and His, M and Boutron-, Ruault M and Peeters, PH and Ye, W and Sund, M and Boeing, H and Iqbal, K and Ohlsson, B and Sonestedt, E and Tjonneland, A and Petersen, KEN and Travis, RC and Skeie, G and Agnoli, C and Agnoli, C and Panico, S and Palli, D and Tumino, R and Sacerdote, C and Freisling, H and Huybrechts, I and Overvad, K and Trichopoulou, A and Bamia, C and Vasilopoulou, E and Wareham, N and Khaw, K and Cross, AJ and Ward, HA and Riboli, E and Duell, EJ},
doi = {10.1038/bjc.2017.14},
journal = {British Journal of Cancer},
pages = {811--820},
title = {Mediterranean Diet and risk of pancreatic cancer in the European Prospective Investigation into Cancer and Nutrition cohort},
url = {http://dx.doi.org/10.1038/bjc.2017.14},
volume = {116},
year = {2017}
}

Download

RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Background:The  Mediterranean  Diet  (MD)  has  been  proposed  as  a  means  for  cancer  prevention,  but  little  evidence  has  been  accrued  regarding  its  potential  to  prevent  pancreatic cancer. We investigated the association between the adherence to the MD and pancreatic cancer risk within the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort. Methods: Over half a million participants from 10 European countries were followed-up for over11  years,  after  which  865  newly  diagnosed  exocrine  pancreatic  cancer  cases  were  identified.  Adherence  to  the  MD  was  estimated  through  an  adapted  score  without  the alcohol  component (arMED) to discount alcohol-related harmful effects. Cox proportional hazards regression models, stratified  by  age,  sex  and  center,  and  adjusted  for  energy  intake,  body  mass  index  (BMI), smoking status, alcohol intake and diabetes status at recruitment, were used to estimate hazardratios   (HRs)   associated with pancreatic cancer and their corresponding 95% confidence intervals 16 (CIs)  . Results:  Adherence to the arMED score was not associated with risk  of  pancreatic cancer (HR high versus  low  adherence  =  0.99;  95%  CI:  0.77-1.26,  and  HR  per  increments  of  2  units  in adherence  to  arMED =  1.00;  95%  CI:  0.94-1.06).  There  was  no  convincing evidence  for  heterogeneity by smoking status, BMI, diabetes or European region. There was also no evidence of significant  associations  in  analyses  involving  microscopically  confirmed  cases,  plausible  reporters of energy intake, or other definitions of the MD pattern.Conclusion:  A  high  adherence  to  the  MD  is  not  associated  with  pancreatic  cancer  risk in  the  EPIC study.
AU  - Molina-Montes,E
AU  - Sánchez,M
AU  - Buckland,G
AU  - Bueno-de-Mesquita,B
AU  - Weiderpass,E
AU  - Amiano,P
AU  - Wark,PA
AU  - Kuhn,T
AU  - Katzke,V
AU  - Huerta,JM
AU  - Ardanaz,E
AU  - Ramón,Quirós J
AU  - Affret,A
AU  - His,M
AU  - Boutron-,Ruault M
AU  - Peeters,PH
AU  - Ye,W
AU  - Sund,M
AU  - Boeing,H
AU  - Iqbal,K
AU  - Ohlsson,B
AU  - Sonestedt,E
AU  - Tjonneland,A
AU  - Petersen,KEN
AU  - Travis,RC
AU  - Skeie,G
AU  - Agnoli,C
AU  - Agnoli,C
AU  - Panico,S
AU  - Palli,D
AU  - Tumino,R
AU  - Sacerdote,C
AU  - Freisling,H
AU  - Huybrechts,I
AU  - Overvad,K
AU  - Trichopoulou,A
AU  - Bamia,C
AU  - Vasilopoulou,E
AU  - Wareham,N
AU  - Khaw,K
AU  - Cross,AJ
AU  - Ward,HA
AU  - Riboli,E
AU  - Duell,EJ
DO  - 10.1038/bjc.2017.14
EP  - 820
PY  - 2017///
SN  - 1532-1827
SP  - 811
TI  - Mediterranean Diet and risk of pancreatic cancer in the European Prospective Investigation into Cancer and Nutrition cohort
T2  - British Journal of Cancer
UR  - http://dx.doi.org/10.1038/bjc.2017.14
UR  - http://hdl.handle.net/10044/1/43955
VL  - 116
ER  -

Download

DrPetraWark

Contact

Location

Summary

Citation

BibTex format

RIS format (EndNote, RefMan)