Imperial College London
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DrPeterWinskill

Faculty of Medicine, School of Public Health

Research Fellow
 
 
 
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Contact

 

p.winskill

 
 
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Location

 

School of Public HealthWhite City Campus

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Summary

 

Publications

Citation

BibTex format

@article{Schmit:2023,
author = {Schmit, N and Topazian, H and Pianella, M and Charles, G and Winskill, P and White, M and Hauck, K and Ghani, A},
journal = {eLife},
title = {Resource allocation strategies to achieve malaria eradication},
url = {http://hdl.handle.net/10044/1/104072},
year = {2023}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Background: Large reductions in the global malaria burden have been achieved in the last decades, but plateauing funding poses a challenge for progressing towards the ultimate goal of malaria eradication. We aimed to determine the optimal strategy to allocate global resources to achieve this goal.Methods: Using previously published mathematical models of Plasmodium falciparum and Plasmodium vivax transmission incorporating insecticide-treated nets (ITNs) as an illustrative intervention, we sought to identify the global funding allocation that maximized impact under defined objectives and across a range of global funding budgets.Results: We found that the optimal strategy for case reduction closely mirrored an allocation framework that prioritizes funding for high-transmission settings, resulting in total case reductions of 76% (optimal strategy) and 66% (prioritizing high-transmission settings) at intermediate budget levels. Allocation strategies that had the greatest impact on case reductions were associated with lesser near-term impacts on the global population at risk, highlighting a trade-off between reducing burden and “shrinking the map” through a focus on near-elimination settings. The optimal funding distribution prioritized high ITN coverage in high-transmission settings endemic for P. falciparum only, while maintaining lower levels in low-transmission settings. However, at high budgets, 62% of funding was targeted to low-transmission settings co-endemic for P. falciparum and P. vivax.Conclusions: These results support current global strategies to prioritize funding to high-burden P. falciparum-endemic settings in sub-Saharan Africa to minimize clinical malaria burden and progress towards elimination but highlight competing goals of reducing the global population at risk and addressing the burden of P. vivax.
AU  - Schmit,N
AU  - Topazian,H
AU  - Pianella,M
AU  - Charles,G
AU  - Winskill,P
AU  - White,M
AU  - Hauck,K
AU  - Ghani,A
PY  - 2023///
SN  - 2050-084X
TI  - Resource allocation strategies to achieve malaria eradication
T2  - eLife
UR  - http://hdl.handle.net/10044/1/104072
ER  -
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