Imperial College London
Portrait Picture

Professor Pantelis Georgiou

Faculty of Engineering, Department of Electrical and Electronic Engineering

Professor of Biomedical Electronics
 
 
 
//

Contact

 

+44 (0)20 7594 6326pantelis Website

 
 
//

Location

 

902Electrical EngineeringSouth Kensington Campus

//

Summary

 

Publications

Citation

BibTex format

@article{Zeng:2020:10.1109/TBCAS.2020.2973508,
author = {Zeng, J and Kuang, L and Miscourides, N and Georgiou, P},
doi = {10.1109/TBCAS.2020.2973508},
journal = {IEEE Transactions on Biomedical Circuits and Systems},
pages = {359--372},
title = {A 128 × 128 current-mode ultra-high frame rate ISFET array with in-pixel calibration for real-time ion imaging.},
url = {http://dx.doi.org/10.1109/TBCAS.2020.2973508},
volume = {14},
year = {2020}
}
Download

RIS format (EndNote, RefMan)

TY  - JOUR
AB  - An ultra-high frame rate and high resolution ion-sensing Lab-on-Chip platform using a 128x128 CMOS ISFETarray is presented. Current mode operation is employed to facilitate high-speed operation, with the ISFET sensors biased in the triode region to provide a linear response. Sensing pixels include a reset switch to allow in pixel-calibration for nonidealities such as offset, trapped charge and drift by periodically resetting the floating gate of the ISFET sensor. Current mode row-parallel signal processing is applied throughout the readout pipeline including auto-zeroing circuits for the removal of fixed pattern noise. The 128 readout signals are multiplexed to eight high-sample-rate on-chip current mode ADCs followed by an off-chip PCIe-based digital readout system on a FPGA with a latency of 0.15s. Designed in a 0.35 um CMOS process, the complete system-on-chip occupies an area of 2.6mm x 2.2mm and the whole system achieves a frame rate of 3000fps which is the highest reported in the literature. The platform is demonstrated for real-time ion-imaging through the high-speed visualisation of sodium hydroxide (NaOH) diffusion in water. Furthermore, the proposed platform is able to achieve real-time visualisation of ion dynamics on a screen at 60fps in addition to slow-motion replay in 3000fps.
AU  - Zeng,J
AU  - Kuang,L
AU  - Miscourides,N
AU  - Georgiou,P
DO  - 10.1109/TBCAS.2020.2973508
EP  - 372
PY  - 2020///
SN  - 1932-4545
SP  - 359
TI  - A 128 × 128 current-mode ultra-high frame rate ISFET array with in-pixel calibration for real-time ion imaging.
T2  - IEEE Transactions on Biomedical Circuits and Systems
UR  - http://dx.doi.org/10.1109/TBCAS.2020.2973508
UR  - https://www.ncbi.nlm.nih.gov/pubmed/32070997
UR  - https://ieeexplore.ieee.org/document/8995651
UR  - http://hdl.handle.net/10044/1/77424
VL  - 14
ER  -
Download