Imperial College London
Alternate

Dr Paras Anand

Faculty of Medicine, Department of Infectious Disease

Senior Lecturer
 
 
 
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Contact

 

+44 (0)20 3313 2063paras.anand Website

 
 
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Location

 

8.N23Commonwealth BuildingHammersmith Campus

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Summary

 

Publications

Citation

BibTex format

@article{Lupfer:2016:10.1016/j.it.2016.08.004,
author = {Lupfer, C and Anand, PK},
doi = {10.1016/j.it.2016.08.004},
journal = {Trends in Immunology},
pages = {703--714},
title = {Integrating inflammasome signaling in sexually transmitted infections},
url = {http://dx.doi.org/10.1016/j.it.2016.08.004},
volume = {37},
year = {2016}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Inflammasomes  are  cytosolic  multiprotein  platforms  with  pivotal  roles  in  infectious  diseases. Activation  of  inflammasomes  results  in  pro-inflammatory  cytokine  signaling  and  pyroptosis. Sexually  transmitted  infections  are  a  major  health  problem  worldwide,  yet few studies  have probed  the  impact  of  inflammasome  signaling  during  these  infections.  Due  to  the  dearth  of appropriate   infection   models,   our   current   understanding   of   inflammasomes   in   sexually transmitted infections is mostly drawn from results obtained in vitro, from distant infection sites, or from   related   microbial   strains   that   are   not   sexually   transmitted.   Understanding   how inflammasomes  influence  the  outcome  of  sexually  transmitted  infections  may  lead  to  the development  of  novel  and  effective  strategies  to  control  disease  and prevent transmission.Here, we discuss and highlight the recent progress in this field.
AU  - Lupfer,C
AU  - Anand,PK
DO  - 10.1016/j.it.2016.08.004
EP  - 714
PY  - 2016///
SN  - 1471-4981
SP  - 703
TI  - Integrating inflammasome signaling in sexually transmitted infections
T2  - Trends in Immunology
UR  - http://dx.doi.org/10.1016/j.it.2016.08.004
UR  - http://hdl.handle.net/10044/1/39728
VL  - 37
ER  -
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