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@article{Diawara:2021:10.1186/s12936-021-03653-x,
author = {Diawara, H and Walker, P and Cairns, M and Steinhardt, LC and Diawara, F and Kamate, B and Duval, L and Sicuri, E and Sagara, I and Sadou, A and Mihigo, J and Eckert, E and Dicko, A and Conteh, L},
doi = {10.1186/s12936-021-03653-x},
journal = {Malaria Journal},
pages = {1--14},
title = {Cost-effectiveness of district-wide seasonal malaria chemoprevention when implemented through routine malaria control programme in Kita, Mali using fixed point distribution},
url = {http://dx.doi.org/10.1186/s12936-021-03653-x},
volume = {20},
year = {2021}
}

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TY  - JOUR
AB  - Background: Seasonal malaria chemoprevention (SMC) is a strategy for malaria control recommended by the World Health Organization (WHO) since 2012 for Sahelian countries. The Mali National Malaria Control Programme adopted a plan for pilot implementation and nationwide scale-up by 2016. Given that SMC is a relatively new approach, there is an urgent need to assess the costs and cost effectiveness of SMC when implemented through the routine health system to inform decisions on resource allocation.Methods: Cost data were collected from pilot implementation of SMC in Kita district, which targeted 77,497 children aged 3–59 months. Starting in August 2014, SMC was delivered by fixed point distribution in villages with the first dose observed each month. Treatment consisted of sulfadoxine-pyrimethamine and amodiaquine once a month for four consecutive months, or rounds. Economic and financial costs were collected from the provider perspective using an ingredients approach. Effectiveness estimates were based upon a published mathematical transmission model calibrated to local epidemiology, rainfall patterns and scale-up of interventions. Incremental cost effectiveness ratios were calculated for the cost per malaria episode averted, cost per disability adjusted life years (DALYs) averted, and cost per death averted.Results: The total economic cost of the intervention in the district of Kita was US $357,494. Drug costs and personnel costs accounted for 34% and 31%, respectively. Incentives (payment other than salary for efforts beyond routine activities) accounted for 25% of total implementation costs. Average financial and economic unit costs per child per round were US $0.73 and US $0.86, respectively; total annual financial and economic costs per child receiving SMC were US $2.92 and US $3.43, respectively. Accounting for coverage, the economic cost per child fully adherent (receiving all four rounds) was US $6.38 and US $4.69, if weighted highly adherent, (receivin
AU  - Diawara,H
AU  - Walker,P
AU  - Cairns,M
AU  - Steinhardt,LC
AU  - Diawara,F
AU  - Kamate,B
AU  - Duval,L
AU  - Sicuri,E
AU  - Sagara,I
AU  - Sadou,A
AU  - Mihigo,J
AU  - Eckert,E
AU  - Dicko,A
AU  - Conteh,L
DO  - 10.1186/s12936-021-03653-x
EP  - 14
PY  - 2021///
SN  - 1475-2875
SP  - 1
TI  - Cost-effectiveness of district-wide seasonal malaria chemoprevention when implemented through routine malaria control programme in Kita, Mali using fixed point distribution
T2  - Malaria Journal
UR  - http://dx.doi.org/10.1186/s12936-021-03653-x
UR  - http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000628770100003&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
UR  - https://malariajournal.biomedcentral.com/articles/10.1186/s12936-021-03653-x
UR  - http://hdl.handle.net/10044/1/88095
VL  - 20
ER  -

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