Publications
230 results found
Edison P, Femminella GD, Harold D, et al., 2020, The Differential Influence of Immune, Endocytotic, and Lipid Metabolism Genes on Amyloid Deposition and Neurodegeneration in Subjects at Risk of Alzheimer's Disease., Alzheimer's Disease Neuroimaging Initiative
Edison P, 2020, Brain Connectivity in Neurodegenerative Diseases, BRAIN CONNECTIVITY, Vol: 10, Pages: 465-466, ISSN: 2158-0014
Edison P, 2020, Brain Connectivity in the Era of Artificial Intelligence, BRAIN CONNECTIVITY, Vol: 10, Pages: 397-398, ISSN: 2158-0014
Edison P, 2020, Brain Connectivity and Cognitive Impairment, BRAIN CONNECTIVITY, Vol: 10, Pages: 329-330, ISSN: 2158-0014
Edison P, 2020, Brain Connectivity: Advances in Neurodegenerative Diseases, BRAIN CONNECTIVITY, Vol: 10, Pages: 251-252, ISSN: 2158-0014
Edison P, 2020, Call for Special Issue Papers: Brain Connectivity Modalities in Alzheimer's Disease., Brain Connect, Vol: 10, Pages: 253-253
Edison P, Kleniuk J, 2020, Association of cardiovascular risk and sex with cortical tau deposition in cognitively normal and at risk Alzheimer's subjects., 2020 Alzheimer's Association International Conference
Edison P, Leng F, Hinz R, et al., 2020, Tau formation is associated with microglial activation in more widespread cortical areas than amyloid deposition does, 2020 Alzheimer's Association International Conference
Edison P, Femminella GD, Livingston NR, et al., 2020, Influence of cerebral glucose metabolic rate on cognitive function in Alzheimer's subjects, 2020 Alzheimer's Association International Conference
Edison P, Femminella GD, Livingston NR, et al., 2020, Influence of cerebral glucose metabolic rate on cognitive function in Alzheimer's subjects., 2020 Alzheimer's Association International Conference
Edison P, Rosa-Neto P, Pascoal TA, et al., 2020, Neuroinflammation imposes vulnerability to tau propagation., 2020 Alzheimer's Association International Conference
Edison P, Calsolaro V, Hinz R, et al., 2020, Microglial activation evaluated using Flutriciclamide (11F-GE180) in subjects with cognitive impairment, 2020 Alzheimer's Association International Conference
Edison P, 2020, Neuroinflammation, microglial activation, and glucose metabolism in neurodegenerative diseases., International Review of Neurobiology, ISSN: 0074-7742
Femminella GD, Frangou E, Love SB, et al., 2020, Evaluating the effects of the novel GLP-1 analogue liraglutide in Alzheimer's disease: study protocol for a randomised controlled trial (ELAD study) (vol 20, 191, 2019), TRIALS, Vol: 21
Edison P, Femminella GD, Frangou E, et al., 2020, Evaluating the effects of the novel GLP-1 analogue liraglutide in Alzheimer's Disease: study protocol for a randomised controlled trial (ELAD study) (vol 20,191,2019), Trials, ISSN: 1745-6215
Edison P, 2020, Call for Special Issue Papers: Brain Connectivity Modalities in Alzheimer's Disease: Deadline for Manuscript Submission: September 15, 2020., Brain Connectivity, ISSN: 2158-0014
Edison P, 2020, Brain Connectivity: Disrupted Structural and Functional Connectivity-Cause or Effect?, BRAIN CONNECTIVITY, Vol: 10, Pages: 200-201, ISSN: 2158-0014
Edison P, 2020, Call for Special Issue Papers: Brain Connectivity Modalities in Alzheimer's Disease., Brain Connect, Vol: 10, Pages: 199-199
Edison P, 2020, Brain Connectivity: A Bidirectional Involvement of Structural Connectivity and Pathological Substrates in Neurodegeneration, BRAIN CONNECTIVITY, Vol: 10, Pages: 155-156, ISSN: 2158-0014
Edison P, 2020, Brain Connectivity: Structural and Functional Neuronal Integrity and Its Relationship with Pathological Substrates, BRAIN CONNECTIVITY, Vol: 10, Pages: 106-107, ISSN: 2158-0014
Edison P, 2020, The Invisible Enemy That Will Change the World Forever, BRAIN CONNECTIVITY, Vol: 10, Pages: 105-105, ISSN: 2158-0014
Edison P, 2020, Brain Connectivity: Neuronal Integrity and Its Relationship with Pathological Substrates, BRAIN CONNECTIVITY, Vol: 10, Pages: 51-52, ISSN: 2158-0014
Edison P, 2020, Brain Connectivity: Structural Integrity and Brain Function, BRAIN CONNECTIVITY, Vol: 10, Pages: 1-2, ISSN: 2158-0014
Edison P, 2020, Neuroinflammation, microglial activation, and glucose metabolism in neurodegenerative diseases, METABOLIC AND BIOENERGETIC DRIVERS OF NEURODEGENERATIVE DISEASE: NEURODEGENERATIVE DISEASE RESEARCH AND COMMONALITIES WITH METABOLIC DISEASES, Vol: 154, Pages: 325-344, ISSN: 0074-7742
Edison P, 2019, Brain Connectivity: The Basis of Neuronal Integrity, BRAIN CONNECTIVITY, Vol: 9, Pages: 743-744, ISSN: 2158-0014
Perani D, Iaccarino L, Jacobs AH, et al., 2019, Application of advanced brain positron emission tomography-based molecular imaging for a biological framework in neurodegenerative proteinopathies., Alzheimers Dement (Amst), Vol: 11, Pages: 327-332, ISSN: 2352-8729
Introduction: A rapid transition from a clinical-based classification to a pathology-based classification of neurodegenerative conditions, largely promoted by the increasing availability of imaging biomarkers, is emerging. The Framework for Innovative Multi-tracer molecular Brain Imaging, funded by the EU Joint Program - Neurodegenerative Disease Research 2016 "Working Groups for Harmonisation and Alignment in Brain Imaging Methods for Neurodegeneration," aimed at providing a roadmap for the applications of established and new molecular imaging techniques in dementia. Methods: We consider current and future implications of adopting a pathology-based framework for the use and development of positron emission tomography techniques. Results: This approach will enhance efforts to understand the multifactorial etiology of Alzheimer's disease and other dementias. Discussion: The availability of pathology biomarkers will soon transform clinical and research practice. Crucially, a comprehensive understanding of strengths and caveats of these techniques will promote an informed use to take full advantage of these tools.
Edison P, 2019, A Note from the Editor-in-Chief, BRAIN CONNECTIVITY, Vol: 9, Pages: 661-661, ISSN: 2158-0014
Schubert JJ, Veronese M, Marchitelli L, et al., 2019, Dynamic 11C-PiB PET shows cerebrospinal fluid flow alterations in Alzheimer's disease and multiple sclerosis, Journal of Nuclear Medicine, Vol: 60, Pages: 1452-1460, ISSN: 1535-5667
Cerebrospinal fluid (CSF) plays an important role in the clearance of solutes and maintenance of brain homeostasis. 11C-PiB PET was recently proposed as a tool for detection of CSF clearance alterations in Alzheimer's disease. The current study seeks to investigate the magnitude of 11C-PiB PET signal in the lateral ventricles of an independent group of Alzheimer's and mild cognitive impairment subjects. We have also evaluated multiple sclerosis as a model of disease with CSF clearance alterations without amyloid-beta tissue accumulation. Methods: A set of Alzheimer's and mild cognitive impairment subjects and a set of multiple sclerosis subjects with matched healthy controls underwent MRI and dynamic 11C-PiB PET. Manual lateral ventricle regions of interest were generated from MRI data. PET data was analysed using a simplified reference tissue model with cerebellum or a supervised reference region, for the Alzheimer's and multiple sclerosis datasets, respectively. Magnitude of 11C-PiB signal in the lateral ventricles was calculated as area under curve from 35 to 80 minutes and standard uptake value ratio (SUVR) from 50 to 70 minutes. Compartmental modelling analysis was performed on a separate dataset containing Alzheimer's and matched healthy control data with an arterial input function to further understand the kinetics of the lateral ventricular 11C-PiB signal. Results: Analysis of variance revealed significant group differences in lateral ventricular SUVR across the Alzheimer's, mild cognitive impairment, and healthy control groups (P = 0.004). Additional pairwise comparisons revealed significantly lower lateral ventricular SUVR in Alzheimer's compared to healthy controls (p<0.001) and mild cognitive impairment (P = 0.029). Lateral ventricular SUVR was also significantly lower in multiple sclerosis compared to healthy controls (P = 0.008). Compartmental modelling analysis revealed significantly lower uptake rates of 11C-PiB signal from blood (P = 0.005) and b
Edison P, 2019, A Note from Our New Editor-in-Chief, BRAIN CONNECTIVITY, Vol: 9, Pages: 593-593, ISSN: 2158-0014
Perani D, Iaccarino L, Lammertsma AA, et al., 2019, A new perspective for advanced positron emission tomography-based molecular imaging in neurodegenerative proteinopathies, ALZHEIMERS & DEMENTIA, Vol: 15, Pages: 1081-1103, ISSN: 1552-5260
- Author Web Link
- Cite
- Citations: 11
This data is extracted from the Web of Science and reproduced under a licence from Thomson Reuters. You may not copy or re-distribute this data in whole or in part without the written consent of the Science business of Thomson Reuters.