Imperial College London


Faculty of Natural SciencesDepartment of Physics

Professor of Physics and Vice Dean (Research) - FoNS



+44 (0)20 7594 7706paul.french Website




Ms Judith Baylis +44 (0)20 7594 7713




609Blackett LaboratorySouth Kensington Campus






BibTex format

author = {Cortés, E and Huidobro, PA and Sinclair, HG and Guldbrand, S and Peveler, WJ and Davies, T and Parrinello, S and Görlitz, F and Dunsby, C and Neil, MAA and Sivan, Y and Parkin, IP and French, PMW and Maier, SA},
doi = {10.1021/acsnano.6b06361},
journal = {ACS Nano},
pages = {10454--10461},
title = {Plasmonic nanoprobes for stimulated emission depletion nanoscopy},
url = {},
volume = {10},
year = {2016}

RIS format (EndNote, RefMan)

AB - Plasmonic nanoparticles influence the absorption and emission processes of nearby emitters due to local enhancements of the illuminating radiation and the photonic density of states. Here, we use the plasmon resonance of metal nanoparticles in order to enhance the stimulated depletion of excited molecules for super-resolved nanoscopy. We demonstrate stimulated emission depletion (STED) nanoscopy with gold nanorods with a long axis of only 26 nm and a width of 8 nm. These particles provide an enhancement of up to 50% of the resolution compared to fluorescent-only probes without plasmonic components irradiated with the same depletion power. The nanoparticle-assisted STED probes reported here represent a ∼2 × 103 reduction in probe volume compared to previously used nanoparticles. Finally, we demonstrate their application toward plasmon-assisted STED cellular imaging at low-depletion powers, and we also discuss their current limitations.
AU - Cortés,E
AU - Huidobro,PA
AU - Sinclair,HG
AU - Guldbrand,S
AU - Peveler,WJ
AU - Davies,T
AU - Parrinello,S
AU - Görlitz,F
AU - Dunsby,C
AU - Neil,MAA
AU - Sivan,Y
AU - Parkin,IP
AU - French,PMW
AU - Maier,SA
DO - 10.1021/acsnano.6b06361
EP - 10461
PY - 2016///
SN - 1936-0851
SP - 10454
TI - Plasmonic nanoprobes for stimulated emission depletion nanoscopy
T2 - ACS Nano
UR -
UR -
VL - 10
ER -