Imperial College London
Alternate

DrPhilipMiller

Faculty of Natural Sciences, Department of Chemistry

Reader in Applied Synthesis
 
 
 
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Contact

 

philip.miller Website

 
 
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Location

 

501kMolecular Sciences Research HubWhite City Campus

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Summary

 

Publications

Citation

BibTex format

@article{Haywood:2018:10.1039/c7md00425g,
author = {Haywood, T and Cesarec, S and Kealey, S and Plisson, C and Miller, P},
doi = {10.1039/c7md00425g},
journal = {MedChemComm},
pages = {1311--1314},
title = {Ammonium [11C]thiocyanate: revised preparation and reactivity studies of a versatile nucleophile for carbon-11 radiolabelling},
url = {http://dx.doi.org/10.1039/c7md00425g},
volume = {9},
year = {2018}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Herein we report the preparation of ammonium [11C]thiocyanate via the reaction of [11C]CS2 with ammonia. The [11C]SCN− ion is demonstrated as a potent nucleophile that can be used to readily generate a range of 11C-labelled thiocyanate molecules in high conversions. Furthermore, novel 11C-labelled thiazolone molecules can be easily prepared from the intermediate α-thiocyanatophenones via an acid mediated cyclisation reaction.
AU  - Haywood,T
AU  - Cesarec,S
AU  - Kealey,S
AU  - Plisson,C
AU  - Miller,P
DO  - 10.1039/c7md00425g
EP  - 1314
PY  - 2018///
SN  - 2040-2503
SP  - 1311
TI  - Ammonium [11C]thiocyanate: revised preparation and reactivity studies of a versatile nucleophile for carbon-11 radiolabelling
T2  - MedChemComm
UR  - http://dx.doi.org/10.1039/c7md00425g
UR  - http://hdl.handle.net/10044/1/60025
VL  - 9
ER  -
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