Philippa is a visiting researcher at Imperial College. She completed a PhD in leukaemia genomics in 2018, and recently finished her first post doc, funded by a Kay Kendall Leukaemia Fund project grant, in 2021.
Philippa's interest is in chromatin modification and non-coding regulatory elements in myeloid leukaemia. She uses various NGS-based methods, such as ChIP-seq, ATAC-seq and chromosome conformation capture-seq (4C). She was given an Early Career Development grant by Leukaemia UK in 2019.
Philippa is also an HCPC registered Clinical Scientist in Genetics and leads the Developmental Disorders at Guy's Hospital, using comparative genomic hybridisation to detect copy number imbalance in children with developmental delay. She was previously the Head of Education and Development for Healthcare Science at the Royal Free London NHS Foundation Trust.
Karadimitris A, 2021, Chromatin-based, in cis and in trans regulatory rewiring underpins distinct oncogenic transcriptomes in multiple myeloma, Nature Communications, Vol:12, ISSN:2041-1723, Pages:1-16
et al., 2021, Optimized protocol for a quantitative SARS-CoV-2 duplex RT-qPCR assay with internal human sample sufficiency control., Journal of Virological Methods, Vol:294, ISSN:0166-0934, Pages:1-7
et al., 2020, Three distinct hematological malignancies from a single germ cell tumor: a case report., Journal of Medical Case Reports, Vol:14, ISSN:1752-1947
et al., 2020, Persistence of Drug-Resistant Leukemic Stem Cells and Impaired NK Cell Immunity in CML Patients Depend on MIR300 Antiproliferative and PP2A-Activating Functions, Blood Cancer Discovery, Vol:1, ISSN:2643-3230, Pages:48-67
et al., 2019, Complete remission with incomplete count recovery (CRi) prior to allogeneic HCT for acute myeloid leukaemia is associated with a high non-relapse mortality., Leukemia, Vol:34, ISSN:1476-5551, Pages:667-670
et al., 2017, Lineage-specific genes are prominent DNA damage hotspots during leukemic transformation of B-cell precursors, Cell Reports, Vol:18, ISSN:2211-1247, Pages:1687-1698