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@article{Zhou:2019:ajcn/nqz067,
author = {Zhou, L and Stamler, J and Chan, Q and Van, Horn L and Daviglus, ML and Dyer, AR and Miura, K and Okuda, N and Wu, Y and Ueshima, H and Elliott, P and Zhao, L and INTERMAP, Research Group},
doi = {ajcn/nqz067},
journal = {American Journal of Clinical Nutrition},
pages = {34--40},
title = {Salt intake and prevalence of overweight/obesity in Japan, China, the United Kingdom, and the United States: the INTERMAP Study},
url = {http://dx.doi.org/10.1093/ajcn/nqz067},
volume = {110},
year = {2019}
}

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TY  - JOUR
AB  - BACKGROUND: Several studies have reported that dietary salt intake may be an independent risk factor for overweight/obesity, but results from previous studies are controversial, reflecting study limitations such as use of a single spot urine or dietary recall to estimate daily salt intake rather than 24-h urine collections, and population samples from only a single country or center. OBJECTIVE: The aim of this study was to use data from the International Study of Macro-/Micro-nutrients and Blood Pressure (INTERMAP Study) to explore the relation between dietary salt intake estimated from 2 timed 24-h urine collections and body mass index (BMI; in kg/m2) as well as prevalence of overweight/obesity in Japan, China, the United Kingdom, and the United States. METHODS: Data were from a cross-sectional study of 4680 men and women aged 40-59 y in Japan (n = 1145), China (n = 839), the United Kingdom (n = 501), and the United States (n = 2195). General linear models were used to obtain the regression coefficients (β) of salt intake associated with BMI. Multivariable logistic regression models were used to determine the ORs and 95% CIs of overweight/obesity associated with a 1-g/d higher dietary salt intake. RESULTS: After adjustment for potential confounding factors including energy intake, salt intake 1 g/d higher was associated with BMI higher by 0.28 in Japan, 0.10 in China, 0.42 in the United Kingdom, and 0.52 in the United States, all P values < 0.001. Salt intake 1 g/d higher was associated with odds of overweight/obesity 21% higher in Japan, 4% higher in China, 29% higher in the United Kingdom, and 24% higher in the United States, all P values < 0.05. CONCLUSIONS: Salt intake is positively associated with BMI and the prevalence of overweight/obesity in Japan, China, the United Kingdom, and the United States. This association needs to be further confirmed in well-designed prospective studies with re
AU  - Zhou,L
AU  - Stamler,J
AU  - Chan,Q
AU  - Van,Horn L
AU  - Daviglus,ML
AU  - Dyer,AR
AU  - Miura,K
AU  - Okuda,N
AU  - Wu,Y
AU  - Ueshima,H
AU  - Elliott,P
AU  - Zhao,L
AU  - INTERMAP,Research Group
DO  - ajcn/nqz067
EP  - 40
PY  - 2019///
SN  - 1938-3207
SP  - 34
TI  - Salt intake and prevalence of overweight/obesity in Japan, China, the United Kingdom, and the United States: the INTERMAP Study
T2  - American Journal of Clinical Nutrition
UR  - http://dx.doi.org/10.1093/ajcn/nqz067
UR  - https://www.ncbi.nlm.nih.gov/pubmed/31111867
UR  - http://hdl.handle.net/10044/1/70200
VL  - 110
ER  -

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