Imperial College London

DrQueenieChan

Faculty of MedicineSchool of Public Health

Honorary Senior Research Fellow
 
 
 
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Contact

 

+44 (0)20 7594 3311q.chan

 
 
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Location

 

151Norfolk PlaceSt Mary's Campus

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Summary

 

Publications

Citation

BibTex format

@article{Kanagasabai:2022:10.1016/j.envres.2022.115117,
author = {Kanagasabai, T and Carter, E and Yan, L and Chan, Q and Elliott, P and Ezzati, M and Kelly, F and Xie, G and Yang, X and Zhao, L and Guo, D and Daskalopoulou, SS and Wu, Y and Baumgartner, J},
doi = {10.1016/j.envres.2022.115117},
journal = {Environmental Research},
pages = {1--11},
title = {Cross-sectional study of household solid fuel use and renal function in older adults in China},
url = {http://dx.doi.org/10.1016/j.envres.2022.115117},
volume = {219},
year = {2022}
}

RIS format (EndNote, RefMan)

TY  - JOUR
AB - BackgroundEmerging evidence links outdoor air pollution and declined renal function but the relationship between household air pollution and renal function is not well understood.MethodsUsing cross-sectional data from the multi-provincial INTERMAP-China Prospective Study, we collected blood samples and questionnaire information on stove use and socio-demographic factors. We calculated estimated glomerular filtration rate (eGFR) from serum creatinine to assess renal function. Participants with eGFR <60 mL/min per 1.73 m2 were defined as having chronic kidney disease (CKD) in this analysis. Generalized estimating equations were used to estimate the association of household fuel with renal function and prevalent CKD in models adjusting for confounders.ResultsAmong the 646 enrolled adults (40-79y; 56% female), one-third exclusively used clean fuel (gas and electric) cookstoves and 11% of northern China participants (n = 49 of 434) used only clean fuel heaters, whereas the rest used solid fuel. In multivariable models, use of solid fuel cookstoves was associated with 0.17 ml/min/1.73 m2 (95% CI: −0.30, 0.64) higher eGFR and 19% (0.86, 1.64) higher prevalence of CKD than exclusive clean fuel use. Greater intensity of solid fuel use was associated with 0.25 ml/min/1.73 m2 (−0.71, 0.21) lower eGFR per 5 stove-use years, though the confidence intervals included the null, while greater current intensity of indoor solid fuel use was associated with 1.02 (1.00, 1.04) higher prevalent CKD per 100 stove-use days per year. Larger associations between current solid fuel use and intensity of use with lower eGFR and prevalent CKD were observed among participants in southern China, those with hypertension or diabetes (eGFR only), and females (CKD only), through these groups had small sample sizes and some confidence intervals included the null.ConclusionWe found inconsistent evidence associating household solid fuel use and renal function in this cross-sectional study o
AU - Kanagasabai,T
AU - Carter,E
AU - Yan,L
AU - Chan,Q
AU - Elliott,P
AU - Ezzati,M
AU - Kelly,F
AU - Xie,G
AU - Yang,X
AU - Zhao,L
AU - Guo,D
AU - Daskalopoulou,SS
AU - Wu,Y
AU - Baumgartner,J
DO - 10.1016/j.envres.2022.115117
EP - 11
PY - 2022///
SN - 0013-9351
SP - 1
TI - Cross-sectional study of household solid fuel use and renal function in older adults in China
T2 - Environmental Research
UR - http://dx.doi.org/10.1016/j.envres.2022.115117
UR - https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000912263600001&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=a2bf6146997ec60c407a63945d4e92bb
UR - https://www.sciencedirect.com/science/article/pii/S0013935122024446?via%3Dihub
UR - http://hdl.handle.net/10044/1/102010
VL - 219
ER -