Publications
582 results found
Marcus ME, Manne-Goehler J, Theilmann M, et al., 2022, Use of statins for the prevention of cardiovascular disease in 41 low-income and middle-income countries: a cross-sectional study of nationally representative, individual-level data, LANCET GLOBAL HEALTH, Vol: 10, Pages: E369-E379, ISSN: 2214-109X
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- Citations: 23
Knaul FM, Touchton MM, Arreola-Ornelas H, et al., 2022, Strengthening Health Systems To Face Pandemics: Subnational Policy Responses To COVID-19 In Latin America, HEALTH AFFAIRS, Vol: 41, Pages: 454-462, ISSN: 0278-2715
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- Citations: 5
Pinto R, Valentim R, da Silva LF, et al., 2022, Use of Interrupted Time Series Analysis in Understanding the Course of the Congenital Syphilis Epidemic in Brazil, LANCET REGIONAL HEALTH-AMERICAS, Vol: 7, ISSN: 2667-193X
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- Citations: 17
Leerapan B, Kaewkamjornchai P, Atun R, et al., 2022, How systems respond to policies: intended and unintended consequences of COVID-19 lockdown policies in Thailand Comment, HEALTH POLICY AND PLANNING, Vol: 37, Pages: 292-293, ISSN: 0268-1080
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- Citations: 4
Ross C, Ward ZJ, Gomber A, et al., 2022, The Prevalence of Islet Autoantibodies in Children and Adolescents With Type 1 Diabetes Mellitus: A Global Scoping Review, FRONTIERS IN ENDOCRINOLOGY, Vol: 13, ISSN: 1664-2392
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- Citations: 12
Vigo D, Jones L, Atun R, et al., 2022, The true global disease burden of mental illness: still elusive Comment, LANCET PSYCHIATRY, Vol: 9, Pages: 98-100, ISSN: 2215-0374
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- Citations: 6
Yerramsetti S, Cohen T, Atun R, et al., 2022, Global estimates of paediatric tuberculosis incidence in 2013-19: a mathematical modelling analysis, LANCET GLOBAL HEALTH, Vol: 10, Pages: E207-E215, ISSN: 2214-109X
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- Citations: 19
Ramadi KB, Mehta R, He D, et al., 2022, Grass-roots entrepreneurship complements traditional top-down innovation in lung and breast cancer, NPJ DIGITAL MEDICINE, Vol: 5, ISSN: 2398-6352
Gomber A, Ward ZJ, Ross C, et al., 2022, Variation in the incidence of type 1 diabetes mellitus in children and adolescents by world region and country income group: A scoping review., PLOS Glob Public Health, Vol: 2
INTRODUCTION: Around 18.7 million of the 537 million people with diabetes worldwide live in low-income and middle-income countries (LMIC), where there is also an increase in the number of children, adolescents, and young adults diagnosed with type 1 diabetes (T1D). There are substantial gaps in data in the current understanding of the epidemiological patterns and trends in incidence rates of T1D at the global level. METHODS: We performed a scoping review of published studies that established the incidence of T1D in children, adolescents, and young adults aged 0-25 years at national and sub-national levels using PubMed, Embase and Global Health. Data was analyzed using R programming. RESULTS: The scoping review identified 237 studies which included T1D incidence estimates from 92 countries, revealing substantial variability in the annual incidence of T1D by age, geographic region, and country-income classification. Highest rates were reported in the 5-9 and 10-14 year age groups than in the 0-4 and 15-19 year age groups, respectively. In the 0-14 year age group, the highest incidence was reported in Northern Europe (23.96 per 100,000), Australia/New Zealand (22.8 per 100,000), and Northern America (18.02 per 100,000), while the lowest was observed in Melanesia, Western Africa, and South America (all < 1 per 100,000). For the 0-19 year age group, the highest incidence was reported in Northern Europe (39.0 per 100,000), Northern America (20.07 per 100,000), and Northern Africa (10.1 per 100,000), while the lowest was observed in Eastern and Western Africa (< 2 per 100,000). Higher incidence rates were observed in high-income countries compared to LMICs. There was a paucity of published studies focusing on determining the incidence of T1D in LMICs. CONCLUSION: The review reveals substantial variability in incidence rates of T1D by geographic region, country income group, and age. There is a dearth of information on T1D in LMICs, particularly in sub-Saharan Africa
Prenissl J, De Neve J-W, Sudharsanan N, et al., 2022, Patterns of multimorbidity in India: A nationally representative cross-sectional study of individuals aged 15 to 49 years., PLOS Glob Public Health, Vol: 2
There is a dearth of evidence on the epidemiology of multimorbidity in low- and middle-income countries. This study aimed to determine the prevalence of multimorbidity in India and its variation among states and population groups. We analyzed data from a nationally representative household survey conducted in 2015-2016 among individuals aged 15 to 49 years. Multimorbidity was defined as having two or more conditions out of five common chronic morbidities in India: anemia, asthma, diabetes, hypertension, and obesity. We disaggregated multimorbidity prevalence by condition, state, rural versus urban areas, district-level wealth, and individual-level sociodemographic characteristics. 712,822 individuals were included in the analysis. The prevalence of multimorbidity was 7·2% (95% CI, 7·1% - 7·4%), and was higher in urban (9·7% [95% CI, 9·4% - 10·1%]) than in rural (5·8% [95% CI, 5·7% - 6·0%]) areas. The three most prevalent morbidity combinations were hypertension with obesity (2·9% [95% CI, 2·8% - 3·1%]), hypertension with anemia (2·2% [95% CI, 2·1%- 2·3%]), and obesity with anemia (1·2% [95% CI, 1·1%- 1·2%]). The age-standardized multimorbidity prevalence varied from 3·4% (95% CI: 3·0% - 3·8%) in Chhattisgarh to 16·9% (95% CI: 13·2% - 21·5%) in Puducherry. Being a woman, being married, not currently smoking, greater household wealth, and living in urban areas were all associated with a higher risk of multimorbidity. Multimorbidity is common among young and middle-aged adults in India. This study can inform screening guidelines for chronic conditions and the targeting of relevant policies and interventions to those most in need.
Basu S, Yudkin JS, Mezhrahid J, et al., 2021, Expanding access to newer medicines for people with type 2 diabetes in low-income and middle-income countries: a cost-effectiveness and price target analysis, LANCET DIABETES & ENDOCRINOLOGY, Vol: 9, Pages: 825-836, ISSN: 2213-8587
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- Citations: 18
Knaul FM, Touchton M, Arreola-Ornelas H, et al., 2021, Punt Politics as Failure of Health System Stewardship: Evidence from the COVID-19 Pandemic Response in Brazil and Mexico, LANCET REGIONAL HEALTH-AMERICAS, Vol: 4, ISSN: 2667-193X
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- Citations: 23
Hricak H, Ward ZJ, Atun R, et al., 2021, Increasing Access to Imaging for Addressing the Global Cancer Epidemic, RADIOLOGY, Vol: 301, Pages: 543-546, ISSN: 0033-8419
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- Citations: 5
Fleming KA, Horton S, Wilson ML, et al., 2021, The <i>Lancet</i> Commission on diagnostics: transforming access to diagnostics, LANCET, Vol: 398, Pages: 1997-2050, ISSN: 0140-6736
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- Citations: 83
Kwete XJ, Berhane Y, Mwanyika-Sando M, et al., 2021, Health priority-setting for official development assistance in low-income and middle-income countries: a Best Fit Framework Synthesis study with primary data from Ethiopia, Nigeria and Tanzania, BMC PUBLIC HEALTH, Vol: 21
Hontelez JAC, Bulstra CA, Yakusik A, et al., 2021, Evidence-based policymaking when evidence is incomplete: The case of HIV programme integration, PLOS MEDICINE, Vol: 18, ISSN: 1549-1277
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- Citations: 4
Bulstra CA, Hontelez JAC, Otto M, et al., 2021, Integrating HIV services and other health services: A systematic review and meta-analysis, PLOS MEDICINE, Vol: 18, ISSN: 1549-1277
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- Citations: 25
Basu S, Flood D, Geldsetzer P, et al., 2021, Estimated effect of increased diagnosis, treatment, and control of diabetes and its associated cardiovascular risk factors among low-income and middle-income countries: a microsimulation model, LANCET GLOBAL HEALTH, Vol: 9, Pages: E1539-E1552, ISSN: 2214-109X
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- Citations: 20
Ward ZJ, Walbaum M, Walbaum B, et al., 2021, Estimating the impact of the COVID-19 pandemic on diagnosis and survival of five cancers in Chile from 2020 to 2030: a simulation-based analysis, LANCET ONCOLOGY, Vol: 22, Pages: 1427-1437, ISSN: 1470-2045
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- Citations: 32
Anindya K, Marthias T, Vellakkal S, et al., 2021, Socioeconomic inequalities in effective service coverage for reproductive, maternal, newborn, and child health: a comparative analysis of 39 low-income and middle-income countries, ECLINICALMEDICINE, Vol: 40
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- Citations: 7
Marcus ME, Ebert C, Geldsetzer P, et al., 2021, Unmet need for hypercholesterolemia care in 35 low- and middle-income countries: A cross-sectional study of nationally representative surveys, PLOS MEDICINE, Vol: 18, ISSN: 1549-1277
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- Citations: 12
Silva S, Arinaminpathy N, Atun R, et al., 2021, Economic impact of tuberculosis mortality in 120 countries and the cost of not achieving the Sustainable Development Goals tuberculosis targets: a full-income analysis, LANCET GLOBAL HEALTH, Vol: 9, Pages: E1372-E1379, ISSN: 2214-109X
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- Citations: 27
Lee TY, Qian C, Zhao Y, et al., 2021, Non-communicable disease risk factors and care cascade management among internal migrant persons in China: systematic review and meta-analysis, BMJ Global Health, Vol: 6, Pages: 1-11, ISSN: 2059-7908
BackgroundIn 2019, there are more than 290 million people who have ever migrated from rural to urban areas in China. These rural-to-urban internal migrants account for more than one-fifth of China’s population and is the largest internal migrant group globally. We present the first systematic review that examines whether internal migrants are more likely to exhibit non-communicable diseases (NCDs) risk factors and have worse NCD management outcomes than non-migrant counterparts in China. MethodsA systematic review was conducted via medical, public health, and economic databases including Scopus, MEDLINE, JSTOR, WHO Library Database, and World Bank e-Library from 2000 to 2020. Study quality was assessed using the National Institute of Health Quality Assessment (NIH QA) tool. We conducted a narrative review and synthesised differences for all studies included, stratified by different types of outcomes. We also conducted random-effects meta-analysis where we had a minimum of two studies with 95% CIs reported. The study protocol has been registered with PROSPERO: CRD 42019139407. ResultsFor most NCD risk factors and care cascade management, comparisons between internal migrants and other populations were either statistically insignificant or inconclusive. While most studies found migrants have a higher prevalence of tobacco use than urban residents, these differences were not statistically significant in the meta-analysis. Although three out four studies suggested that migrants may have worse access to NCD treatment and both studies suggested migrants have lower blood pressure control rates than non-migrants, these findings were not statistically significant.ConclusionFindings from this systematic review demonstrate that there is currently insufficient evidence on migrant and non-migrant differences in NCD risk factors and management in China. Further research is expected to investigate access to healthcare among internal and its effect on both their NCD outcomes
Ward ZJ, Atun R, Hricak H, et al., 2021, The impact of scaling up access to treatment and imaging modalities on global disparities in breast cancer survival: a simulation-based analysis, LANCET ONCOLOGY, Vol: 22, Pages: 1301-1311, ISSN: 1470-2045
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- Citations: 11
Ramos P, Savage C, Thor J, et al., 2021, It takes two to dance the VBHC tango: A multiple case study of the adoption of value-based strategies in Sweden and Brazil, SOCIAL SCIENCE & MEDICINE, Vol: 282, ISSN: 0277-9536
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- Citations: 5
Teufel F, Seiglie JA, Geldsetzer P, et al., 2021, Body-mass index and diabetes risk in 57 low-income and middle-income countries: a cross-sectional study of nationally representative, individual-level data in 685 616 adults, LANCET, Vol: 398, Pages: 238-248, ISSN: 0140-6736
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- Citations: 51
Geerts JM, Kinnair D, Taheri P, et al., 2021, Guidance for Health Care Leaders During the Recovery Stage of the COVID-19 Pandemic A Consensus Statement, JAMA NETWORK OPEN, Vol: 4, ISSN: 2574-3805
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- Citations: 25
Kirschbaum TK, Theilmann M, Sudharsanan N, et al., 2021, Targeting Hypertension Screening in Low- and Middle-Income Countries: A Cross-Sectional Analysis of 1.2 Million Adults in 56 Countries, JOURNAL OF THE AMERICAN HEART ASSOCIATION, Vol: 10
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- Citations: 2
Zhu J, Ferlie E, Castro-Sánchez E, et al., 2021, Macro level factors influencing strategic responses to emergent pandemics: a scoping review, Journal of Global Health, Vol: 11, Pages: 1-16, ISSN: 2047-2978
Background: Strategic planning is critical for successful pandemic management. This study aimed to identify and review the scope and analytic depth of situation analyses conducted to understand their utility, and capture the documented macro-level factors impacting4pandemic management. Methods: To synthesise this disparate body of literature, we adopted a two-step search and 6review process. A systematic search of the literature was conducted to identify all studies since 2000, that have 1) employed a situation analysis;and2) examined contextual factors influencing pandemic management. The included studies are analysed using a seven-domain systems approach rom the discipline of strategic management. Findings: Nineteen studies were included in the final review ranging from single country (6) to regional, multi-country studies (13). Fourteen studies had a single disease focus, with 5 studies evaluating responses to one or more of COVID-19, Severe Acute Respiratory Syndrome (SARS), Middle East Respiratory Syndrome (MERS),Influenza A (H1N1),Ebola virus disease, and Zika virus disease pandemics. Six studies examined a single domain from political, economic, sociological, technological, ecological or wider industry(PESTELI), 5 studies examined two to four domains, and8studies examined five or more domains. Methods employed were predominantly literature reviews. The recommendations focus predominantly on addressing inhibitors in the sociological and technological domains with few recommendations articulated in the political domain. Overall, the legislative domain is least represented. Conclusions: Ex-post analysis using the seven-domain strategic management framework provides further opportunities for a planned systematic response to pandemics which remains critical as the current COVID-19 pandemic evolves.
Ahmad R, Atun R, Birgand G, et al., 2021, Macro level influences on strategic responses to the COVID-19 pandemic – an international survey and tool for national assessments, Journal of Global Health, Vol: 11, Pages: 1-11, ISSN: 2047-2978
Background Variation in the approaches taken to contain the SARS-CoV-2 (COVID-19) pandemic at country level has been shaped by economic and political considerations, technical capacity, and assumptions about public behaviours. To address the limited application of learning from previous pandemics, this study aimed to analyse perceived facilitators and inhibitors during the pandemic and to inform the development of an assessment tool for pandemic response planning.Methods A cross-sectional electronic survey of health and non-healthcare professionals (5 May - 5 June 2020) in six languages, with respondents recruited via email, social media and website posting. Participants were asked to score inhibitors (-10 to 0) or facilitators (0 to +10) impacting country response to COVID-19 from the following domains – Political, Economic, Sociological, Technological, Ecological, Legislative, and wider Industry (the PESTELI framework). Participants were then asked to explain their responses using free text. Descriptive and thematic analysis was followed by triangulation with the literature and expert validation to develop the assessment tool, which was then compared with four existing pandemic planning frameworks.Results 928 respondents from 66 countries (57% healthcare professionals) participated. Political and economic influences were consistently perceived as powerful negative forces and technology as a facilitator across high- and low-income countries. The 103-item tool developed for guiding rapid situational assessment for pandemic planning is comprehensive when compared to existing tools and highlights the interconnectedness of the 7 domains. Conclusions The tool developed and proposed addresses the problems associated with decision making in disciplinary silos and offers a means to refine future use of epidemic modelling.
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