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@article{Kelleher:2021:10.1002/14651858.CD013534.pub2,
author = {Kelleher, MM and Cro, S and Cornelius, V and Lodrup, Carlsen KC and Skjerven, HO and Rehbinder, EM and Lowe, AJ and Dissanayake, E and Shimojo, N and Yonezawa, K and Ohya, Y and Yamamoto-Hanada, K and Morita, K and Axon, E and Surber, C and Cork, M and Cooke, A and Tran, L and Van, Vogt E and Schmitt, J and Weidinger, S and McClanahan, D and Simpson, E and Duley, L and Askie, LM and Chalmers, JR and Williams, HC and Boyle, RJ},
doi = {10.1002/14651858.CD013534.pub2},
journal = {Cochrane Database of Systematic Reviews},
pages = {1--165},
title = {Skin care interventions in infants for preventing eczema and food allergy.},
url = {http://dx.doi.org/10.1002/14651858.CD013534.pub2},
volume = {2021},
year = {2021}
}

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TY  - JOUR
AB  - BACKGROUND: Eczema and food allergy are common health conditions that usually begin in early childhood and often occur together in the same people. They can be associated with an impaired skin barrier in early infancy. It is unclear whether trying to prevent or reverse an impaired skin barrier soon after birth is effective in preventing eczema or food allergy. OBJECTIVES: Primary objective To assess effects of skin care interventions, such as emollients, for primary prevention of eczema and food allergy in infants Secondary objective To identify features of study populations such as age, hereditary risk, and adherence to interventions that are associated with the greatest treatment benefit or harm for both eczema and food allergy. SEARCH METHODS: We searched the following databases up to July 2020: Cochrane Skin Specialised Register, CENTRAL, MEDLINE, and Embase. We searched two trials registers and checked reference lists of included studies and relevant systematic reviews for further references to relevant randomised controlled trials (RCTs). We contacted field experts to identify planned trials and to seek information about unpublished or incomplete trials. SELECTION CRITERIA: RCTs of skin care interventions that could potentially enhance skin barrier function, reduce dryness, or reduce subclinical inflammation in healthy term (> 37 weeks) infants (0 to 12 months) without pre-existing diagnosis of eczema, food allergy, or other skin condition were included. Comparison was standard care in the locality or no treatment. Types of skin care interventions included moisturisers/emollients; bathing products; advice regarding reducing soap exposure and bathing frequency; and use of water softeners. No minimum follow-up was required. DATA COLLECTION AND ANALYSIS: This is a prospective individual participant data (IPD) meta-analysis. We used standard Cochrane methodological procedures, and primary ana
AU  - Kelleher,MM
AU  - Cro,S
AU  - Cornelius,V
AU  - Lodrup,Carlsen KC
AU  - Skjerven,HO
AU  - Rehbinder,EM
AU  - Lowe,AJ
AU  - Dissanayake,E
AU  - Shimojo,N
AU  - Yonezawa,K
AU  - Ohya,Y
AU  - Yamamoto-Hanada,K
AU  - Morita,K
AU  - Axon,E
AU  - Surber,C
AU  - Cork,M
AU  - Cooke,A
AU  - Tran,L
AU  - Van,Vogt E
AU  - Schmitt,J
AU  - Weidinger,S
AU  - McClanahan,D
AU  - Simpson,E
AU  - Duley,L
AU  - Askie,LM
AU  - Chalmers,JR
AU  - Williams,HC
AU  - Boyle,RJ
DO  - 10.1002/14651858.CD013534.pub2
EP  - 165
PY  - 2021///
SN  - 1469-493X
SP  - 1
TI  - Skin care interventions in infants for preventing eczema and food allergy.
T2  - Cochrane Database of Systematic Reviews
UR  - http://dx.doi.org/10.1002/14651858.CD013534.pub2
UR  - https://www.ncbi.nlm.nih.gov/pubmed/33545739
UR  - https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD013534.pub2/full
UR  - http://hdl.handle.net/10044/1/86915
VL  - 2021
ER  -

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