Imperial College London
DR ROBERTO DINA MD, FIAC, FRCPath

DR ROBERTO DINA MD, FIAC, FRCPath

Faculty of Medicine, Department of Metabolism, Digestion and Reproduction

Honorary Clinical Senior Lecturer
 
 
 
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Contact

 

+44 (0)7753 719 480r.dina Website

 
 
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Location

 

Hammersmith HospitalHammersmith Campus

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Summary

 

Publications

Citation

BibTex format

@article{Mizamtsidi:2018:10.1530/EC-17-0283,
author = {Mizamtsidi, M and Nastos, C and Mastorakos, G and Dina, R and Vassiliou, I and Gazouli, M and Palazzo, F},
doi = {10.1530/EC-17-0283},
journal = {Endocrine Connections},
pages = {R56--R68},
title = {Diagnosis, management, histology and genetics of sporadic primary hyperparathyroidism: old knowledge with new tricks},
url = {http://dx.doi.org/10.1530/EC-17-0283},
volume = {7},
year = {2018}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Primary hyperparathyroidism (pHPT) is a common endocrinopathy resulting from inappropriately high PTH secretion. It usually results from the presence of a single gland adenoma, multiple gland hyperplasia or rarely parathyroid carcinoma. All these conditions require different management and it is important to be able to differentiate the underlined pathology, in order for the clinicians to provide the best therapeutic approach. Elucidation of the genetic background of each of these clinical entities would be of great interest. However, the molecular factors that control parathyroid tumorigenesis are poorly understood. There are data implicating the existence of specific genetic pathways involved in the emergence of parathyroid tumorigenesis. The main focus of the present study is to present the current optimal diagnostic and management protocols for pHPT as well as to review the literature regarding all molecular and genetic pathways that are be involved in the pathophysiology of sporadic pHPT.
AU  - Mizamtsidi,M
AU  - Nastos,C
AU  - Mastorakos,G
AU  - Dina,R
AU  - Vassiliou,I
AU  - Gazouli,M
AU  - Palazzo,F
DO  - 10.1530/EC-17-0283
EP  - 68
PY  - 2018///
SN  - 2049-3614
SP  - 56
TI  - Diagnosis, management, histology and genetics of sporadic primary hyperparathyroidism: old knowledge with new tricks
T2  - Endocrine Connections
UR  - http://dx.doi.org/10.1530/EC-17-0283
UR  - http://hdl.handle.net/10044/1/56087
VL  - 7
ER  -
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