DrRosemaryFisher

Fisher RA, Savage PM, MacDermott C, Hook J, Sebire NJ, Lindsay I, Seckl MJet al., 2007, The impact of molecular genetic diagnosis on the management of women with hCG-producing malignancies, GYNECOLOGIC ONCOLOGY, Vol: 107, Pages: 413-419, ISSN: 0090-8258

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• Citations: 62

Fisher RA, 2007, Familial Recurrent Hydatidiform Mole, XIV World Congress on Gestational Trophoblastic Diseases

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Oladipo A, Mathew J, Oriolowo A, Lindsay I, Fisher R, Seckl M, Yiannakis Det al., 2007, Nongestational choriocarcinoma arising from a primary ovarian tumour, BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, Vol: 114, Pages: 1298-1300, ISSN: 1470-0328

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• Citations: 12

Palmieri C, Dhillon T, Fisher RA, Young A-M, Short D, Mitchell H, Aghajanian C, Savage PM, Newlands ES, Hancock BW, Seckl MJet al., 2007, Management and outcome of healthy women with a persistently elevated β-hCG, GYNECOLOGIC ONCOLOGY, Vol: 106, Pages: 35-43, ISSN: 0090-8258

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• Citations: 20

Fisher RA, Sebire NJ, 2007, Recurrent Molar Pregnancies, Recurrent Pregnancy Loss, Editors: Arora, Konje, New Delhi, Publisher: Jaypee Medical Publishers, Pages: 46-53

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Burke B, Sebire NJ, Moss J, Hodges MD, Seckl MJ, Newlands ES, Fisher RAet al., 2006, Evaluation of deletions in 7q11.2 and 8p12-p21 as prognostic indicators of tumour development following molar pregnancy, GYNECOLOGIC ONCOLOGY, Vol: 103, Pages: 642-648, ISSN: 0090-8258

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• Citations: 13

Zhao J, Xiang Y, Huang S-Z, Wan X-R, Cui Q-C, Seckl MJ, Fisher RAet al., 2006, [Genetic heterogeneity for familial recurrent hydatidiform mole]., Zhonghua Yi Xue Yi Chuan Xue Za Zhi, Vol: 23, Pages: 511-514, ISSN: 1003-9406

OBJECTIVE: To determine the parental origin of the genome in the molar pregnancies of two familes with familial recurrent hydatidiform mole (FRHM) and to investigate whether the gene responsible for FRHM is likely to be located within the 19q13.4 region in these familes. METHODS: The features of complete hydatidiform mole (CHM) were confirmed by pathological examination. DNA of CHM was prepared from sections of formalin-fixed paraffin-embedded blocks of molar tissue following laser capture microdissection. The polymerace chain reaction was used to amplify microsatellite polymorphisms in DNA from the patients, their husbands and the captured molar tissue. Parental contributions to the molar tissue were determined using ABI 310 GeneScan software. Genotyping and haplotype analysis of the candidate region on 19q13.4 was performed for members of both families using 25 microsatellite markers. RESULTS: One CHM from each family was identified as a biparental complete hydatidiform mole. All patients were heterozygous for most of the markers in the chromosome region of interest. In addition the two affected sisters in one of the families had different genotypes for the 19q13.4 region, suggesting that mutations in a different locus might be responsible for the disorder in this family. CONCLUSION: The location of the gene responsible for FRHM is unlikely to be located in the 19q13.4 chromosomal region in these two families suggesting that FRHM shows genetic heterogeneity.

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Berkowitz RS, Kohorn EI, Goldstein DP, Fisher RAet al., 2006, Advances in the management of gestational trophoblastic disease - Presentations from the XIIIth World Congress on Gestational Trophoblastic Disease, JOURNAL OF REPRODUCTIVE MEDICINE, Vol: 51, Pages: 759-759, ISSN: 0024-7758

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Nagai Y, Sebire NJ, Paradinas FJ, Fisher RA, Newlands ES, Savage PM, Seckl Jet al., 2006, Placental site trophoblastic tumor (PSTT) treated at Charing Cross Hospital over 30 years, 12th Meeting of the International-Federation-of-Placenta-Association, Publisher: W B SAUNDERS CO LTD, Pages: A56-A56, ISSN: 0143-4004

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van der Smagt JJ, Scheenjes E, Kremer JAM, Hennekam FAM, Fisher RAet al., 2006, Heterogeneity in the origin of recurrent complete hydatidiform moles: not all women with multiple molar pregnancies have biparental moles, BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, Vol: 113, Pages: 725-728, ISSN: 1470-0328

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• Citations: 14

Khan S, Dancey G, Lindsay I, Sebire NJ, Fisher RA, Seckl MJ, Savage Pet al., 2006, Placental site trophoblastic tumour derived from an oocyte donation pregnancy, BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, Vol: 113, Pages: 344-346, ISSN: 1470-0328

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• Citations: 6

Zhao J, Moss J, Sebire NJ, Cui QC, Seckl MJ, Xiang Y, Fisher RAet al., 2006, Analysis of the chromosomal region 19q13.4 in two Chinese families with recurrent hydatidiform mole, HUMAN REPRODUCTION, Vol: 21, Pages: 536-541, ISSN: 0268-1161

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• Citations: 16

Fisher RA, Sebire NJ, 2006, Gestational trophoblastic disease, Biology and pathology of trophoblast, Editors: Moffett, Loke, McLaren, Publisher: Cambridge University Press, Pages: 74-110

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Sebire NJ, Fisher RA, 2005, Partly molar pregnancies that are not partial moles: Additional possibilities and implications, PEDIATRIC AND DEVELOPMENTAL PATHOLOGY, Vol: 8, Pages: 732-733, ISSN: 1093-5266

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• Citations: 5

Palmieri C, Fisher RA, Sebire NJ, Lindsay I, Smith JR, McCluggage WG, Savage P, Seckl MJet al., 2005, Placental site trophoblastic tumour arising from a partial hydatidiform mole, LANCET, Vol: 366, Pages: 688-688, ISSN: 0140-6736

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• Citations: 31

Sebire NJ, Lindsay I, Fisher RA, Savage P, Seckl MJet al., 2005, Overdiagnosis of complete and partial hydatidiform mole in tubal ectopic pregnancies, INTERNATIONAL JOURNAL OF GYNECOLOGICAL PATHOLOGY, Vol: 24, Pages: 260-264, ISSN: 0277-1691

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• Citations: 39

Palmieri C, Fisher RA, Sebire NJ, Smith JR, Newlands ESet al., 2005, Placental-site trophoblastic tumour: an unusual presentation with bilateral ovarian involvement, The Lancet Oncology, Vol: 6, Pages: 59-61, ISSN: 1470-2045

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Palmieri C, Fisher RA, Sebire NJ, Smith JR, Newlands ESet al., 2005, Placental-site trophoblastic tumour: an unusual presentation with bilateral ovarian involvement, LANCET ONCOLOGY, Vol: 6, Pages: 59-61, ISSN: 1470-2045

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• Citations: 6

Fisher RA, Sebire NJ, 2005, Gestational trophoblastic disease, Biology and Pathology of Trophoblast, Editors: Moffett, Loke, McClaren, Publisher: Cambridge University Press

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Sebire NJ, Foskett M, Fisher RA, Lindsay I, Seckl MJet al., 2005, Persistent gestational trophoblastic disease is rarely, if ever, derived from non-molar first-trimester miscarriage, MEDICAL HYPOTHESES, Vol: 64, Pages: 689-693, ISSN: 0306-9877

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• Citations: 14

Fisher RA, Nucci MR, Thaker HM, Weremowicz S, Genest DR, Castrillon DHet al., 2004, Complete hydatidiform mole retaining a chromosome 11 of maternal origin: molecular genetic analysis of a case, MODERN PATHOLOGY, Vol: 17, Pages: 1155-1160, ISSN: 0893-3952

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• Citations: 56

Fisher RA, Hodges MD, Newlands ES, 2004, Familial recurrent hydatidiform mole - A review, JOURNAL OF REPRODUCTIVE MEDICINE, Vol: 49, Pages: 595-601, ISSN: 0024-7758

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• Citations: 64

Sebire NJ, Rees HC, Peston D, Seckl MJ, Newlands ES, Fisher RAet al., 2004, p57<SUP>KIP2</SUP> immunohistochemical staining of gestational trophoblastic tumours does not identify the type of the causative pregnancy, HISTOPATHOLOGY, Vol: 45, Pages: 135-141, ISSN: 0309-0167

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• Citations: 20

Hodges MD, Rees HC, Seckl MJ, Newlands ES, Fisher RAet al., 2003, Genetic refinement and physical mapping of a biparental complete hydatidiform mole locus on chromosome 19q13.4, JOURNAL OF MEDICAL GENETICS, Vol: 40, ISSN: 0022-2593

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• Citations: 41

Fisher RA, Hodges MD, 2003, Genomic imprinting in gestational trophoblastic disease - A review, PLACENTA, Vol: 24, Pages: S111-S118, ISSN: 0143-4004

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• Citations: 44

Sebire NJ, Makrydimas G, Agnantis NJ, Zagorianakou N, Rees H, Fisher RAet al., 2003, Updated diagnostic criteria for partial and complete hydatidiform moles in early pregnancy, ANTICANCER RESEARCH, Vol: 23, Pages: 1723-1728, ISSN: 0250-7005

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• Citations: 69

Sebire N, 2003, Risk of recurrent hydatidiform mole and subsequent pregnancy outcome following complete or partial hydatidiform molar pregnancy, BJOG: An International Journal of Obstetrics and Gynaecology, Vol: 110, Pages: 22-26, ISSN: 1470-0328

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Sebire NJ, Fisher RA, Foskett M, Rees H, Seckl MJ, Newlands ESet al., 2003, Risk of recurrent hydatidiform mole and subsequent pregnancy outcome following complete or partial hydatidiform molar pregnancy, BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, Vol: 110, Pages: 22-26, ISSN: 1470-0328

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• Citations: 119

Fisher RA, 2003, Genetic origin and diagnosis of gestational trophoblastic disease, Gestational Trophoblastic Disease, Editors: Hancock, Newlands, Berkowitz, Cole, Publisher: http://www.isstd.org, Pages: 6-38

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Fisher RA, Hodges MD, Rees HC, Sebire NJ, Seckl MJ, Newlands ES, Genest DR, Castrillon DHet al., 2002, The maternally transcribed gene p57<SUP>KIP2</SUP> (<i>CDNK1C</i>) is abnormally expressed in both androgenetic and biparental complete hydatidiform moles, HUMAN MOLECULAR GENETICS, Vol: 11, Pages: 3267-3272, ISSN: 0964-6906

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• Citations: 109