Imperial College London

ProfessorRobertGoldin

Faculty of MedicineDepartment of Metabolism, Digestion and Reproduction

Professor of Liver & GI Pathology
 
 
 
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Contact

 

+44 (0)20 3312 1305r.goldin CV

 
 
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Location

 

Department of Cellular PathologyClarence WingSt Mary's Campus

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Summary

 

Summary

CURRENT RESEARCH ACTIVITIES

I am a histopathologist specialising in gastro-intestinal and liver disease and am involved in clinical work, teaching and research. I am based at Imperial but also work at the Ludwig Insitute for Cancer Research, University of Oxford with Professor Xin Lu. 

At Imperial, my major research collaborations are with Profesor Hanna (upper GI), Professor Mark Thursz (liver) and Professor Zoltan Takats (metabonomics). 

Overall, my main interest is in developing new techniques for extracting information from tissue samples including using, mainly,  metabanomic and digital pathology approaches. This also involves the phenotyping of mouse models of liver disease.



Selected Publications

Journal Articles

Alexander J, Gildea L, Balog J, et al., 2016, A novel methodology for in vivo endoscopic phenotyping of colorectal cancer based on real-time analysis of the mucosal lipidome: a prospective observational study of the iKnife, Surgical Endoscopy and Other Interventional Techniques, Vol:31, ISSN:1432-2218, Pages:1361-1370

Abbassi-Ghadi N, Jones EA, Gomez-Romero M, et al., 2015, A Comparison of DESI-MS and LC-MS for the Lipidomic Profiling of Human Cancer Tissue, Journal of the American Society for Mass Spectrometry, Vol:27, ISSN:1044-0305, Pages:255-264

Zauri M, Berridge G, Thezenas M-L, et al., 2015, CDA directs metabolism of epigenetic nucleosides revealing a therapeutic window in cancer, Nature, Vol:524, ISSN:0028-0836, Pages:114-U269

Antoniades C, 2013, Secretory Leukocyte Protease Inhibitor: a pivotal mediator of anti-inflammatory responses in acetaminophen induced acute liver failure, Hepatology

Wang XD, Lapi E, Sullivan A, et al., 2011, SUMO-modified nuclear cyclin D1 bypasses Ras-induced senescence, Cell Death and Differentiation, Vol:18, ISSN:1350-9047, Pages:304-314

Anstee QM, Concas D, Kudo H, et al., 2010, Impact of pan-caspase inhibition in animal models of established steatosis and non-alcoholic steatohepatitis, Journal of Hepatology, Vol:53, ISSN:0168-8278, Pages:542-550

Levene AP, Kudo H, Thursz MR, et al., 2010, Is Oil Red-O Staining and Digital Image Analysis the Gold Standard for Quantifying Steatosis in the Liver?, Hepatology, Vol:51, ISSN:0270-9139, Pages:1859-1859

Levene AP, Goldin RD, 2010, Physiological hepatic nuclear vacuolation-how long does it persist?, Histopathology, Vol:56, ISSN:0309-0167, Pages:426-429

Conference

Alazawi W, Heath H, Petts G, et al., 2015, STAT2 IS A KEY INFLAMMATORY MOLECULE IN HUMAN NON-ALCOHOLIC FATTY LIVER DISEASE AND MURINE LIVER INJURY, 2nd Digestive-Disorders-Federation Conference, BMJ PUBLISHING GROUP, Pages:A452-A453, ISSN:0017-5749

More Publications