Imperial College London

DrRobertKypta

Faculty of MedicineDepartment of Surgery & Cancer

Senior Lecturer in Cancer Biology
 
 
 
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Contact

 

r.kypta Website

 
 
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Location

 

4007Institute of Reproductive and Developmental BiologyHammersmith Campus

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Summary

 

Summary

  • BA Biochemistry, University of Oxford
  • PhD Molecular Biology, EMBL, Heidelberg
  • Postdoctoral research fellow, University of California San Francisco
  • Wellcome Trust Career Development Fellow, MRC Laboratory for Molecular Cell Biology, UCL
  • Senior Lecturer in Cancer Biology, Imperial College

Research Interests

  • Regulation of the tumour microenvironment by DKK3
  • Targeting Wnt signalling in cancer

TEACHING ACTIVITIES


Publications

Journals

Spethmann T, Böckelmann LC, Labitzky V, et al., 2021, Opposing prognostic relevance of junction plakoglobin in distinct prostate cancer patient subsets, Molecular Oncology, Vol:15, ISSN:1574-7891, Pages:1956-1969

Sunters A, Armstrong VJ, Zaman G, et al., 2021, Mechano-transduction in Osteoblastic Cells Involves Strain-regulated Estrogen Receptor alpha-mediated Control of Insulin-like Growth Factor (IGF) I Receptor Sensitivity to Ambient IGF, Leading to Phosphatidylinositol 3-Kinase/AKT-dependent Wnt/LRP5 Receptor-independent Activation of beta-Catenin Signaling, Journal of Biological Chemistry, Vol:285, ISSN:0021-9258, Pages:8743-8758

Gorroño-Etxebarria I, Aguirre U, Sanchez S, et al., 2019, Wnt-11 as a potential prognostic biomarker and therapeutic target in colorectal cancer, Cancers, Vol:11, ISSN:2072-6694

Ormaza G, Rodríguez JA, de Opakua AI, et al., 2019, The tumor suppressor ING5 is a dimeric, bivalent recognition molecule of the histone H3K4me3 mark, Journal of Molecular Biology, Vol:431, ISSN:0022-2836, Pages:2298-2319

Domenici G, Aurrekoetxea-Rodríguez I, Simões BM, et al., 2019, A Sox2–Sox9 signalling axis maintains human breast luminalprogenitor and breast cancer stem cells, Oncogene, Vol:38, ISSN:0950-9232, Pages:3151-3169

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