Summary
- BA Biochemistry, University of Oxford
- PhD Molecular Biology, EMBL, Heidelberg
- Postdoctoral research fellow/HHMI Research Associate, University of California San Francisco
- Wellcome Trust Career Development Fellow, MRC Laboratory for Molecular Cell Biology, University College London
- Senior Lecturer in Cancer Biology, Imperial College
Research Interests
- Targeting Wnt signalling in cancer
- Regulation of the tumour microenvironment by DKK3
TEACHING ACTIVITIES
- Course Director Cancer Frontiers Intercalated BSc
- Deputy Module Lead Cancer Biology BSc Medical Biosciences
- Lecturer BSc Biomedical Sciences
- Project Supervisor and examiner MRes Cancer Biology
Publications
Journals
Stoletov K, Sanchez S, Gorrono I, et al., 2023, Intravital imaging of Wnt/β-catenin and ATF2-dependent signalling pathways during tumour cell invasion and metastasis, Journal of Cell Science, Vol:136, ISSN:0021-9533
Al Shareef Z, Ershaid MNA, Mudhafar R, et al., 2022, Dickkopf-3: an update on a potential regulator of the tumor microenvironment, Cancers, Vol:14, ISSN:2072-6694, Pages:1-16
Lewis A, Sánchez S, Berti G, et al., 2022, Small-molecule Wnt inhibitors are a potential novel therapy for intestinal fibrosis in Crohns disease, Clinical Science, Vol:136, ISSN:0143-5221, Pages:1405-1423
Spethmann T, Böckelmann LC, Labitzky V, et al., 2021, Opposing prognostic relevance of junction plakoglobin in distinct prostate cancer patient subsets, Molecular Oncology, Vol:15, ISSN:1574-7891, Pages:1956-1969
Sunters A, Armstrong VJ, Zaman G, et al., 2021, Mechano-transduction in Osteoblastic Cells Involves Strain-regulated Estrogen Receptor alpha-mediated Control of Insulin-like Growth Factor (IGF) I Receptor Sensitivity to Ambient IGF, Leading to Phosphatidylinositol 3-Kinase/AKT-dependent Wnt/LRP5 Receptor-independent Activation of beta-Catenin Signaling, Journal of Biological Chemistry, Vol:285, ISSN:0021-9258, Pages:8743-8758