Imperial College London


Faculty of MedicineDepartment of Surgery & Cancer

Senior Lecturer in Cancer Biology



r.kypta Website




4007Institute of Reproductive and Developmental BiologyHammersmith Campus





  • BA Biochemistry, University of Oxford
  • PhD Molecular Biology, EMBL, Heidelberg
  • Postdoctoral research fellow/HHMI Research Associate, University of California San Francisco
  • Wellcome Trust Career Development Fellow, MRC Laboratory for Molecular Cell Biology, University College London
  • Senior Lecturer in Cancer Biology, Imperial College

Research Interests

  • Targeting Wnt signalling using antibody nanoparticles
  • Regulation of the tumour microenvironment by Dickkopf-3




Stoletov K, Sanchez S, Gorrono I, et al., 2023, Intravital imaging of Wnt/β-catenin and ATF2-dependent signalling pathways during tumour cell invasion and metastasis, Journal of Cell Science, Vol:136, ISSN:0021-9533

Al Shareef Z, Ershaid MNA, Mudhafar R, et al., 2022, Dickkopf-3: an update on a potential regulator of the tumor microenvironment, Cancers, Vol:14, ISSN:2072-6694, Pages:1-16

Lewis A, Sánchez S, Berti G, et al., 2022, Small-molecule Wnt inhibitors are a potential novel therapy for intestinal fibrosis in Crohns disease, Clinical Science, Vol:136, ISSN:0143-5221, Pages:1405-1423

Spethmann T, Böckelmann LC, Labitzky V, et al., 2021, Opposing prognostic relevance of junction plakoglobin in distinct prostate cancer patient subsets, Molecular Oncology, Vol:15, ISSN:1574-7891, Pages:1956-1969

Sunters A, Armstrong VJ, Zaman G, et al., 2021, Mechano-transduction in Osteoblastic Cells Involves Strain-regulated Estrogen Receptor alpha-mediated Control of Insulin-like Growth Factor (IGF) I Receptor Sensitivity to Ambient IGF, Leading to Phosphatidylinositol 3-Kinase/AKT-dependent Wnt/LRP5 Receptor-independent Activation of beta-Catenin Signaling, Journal of Biological Chemistry, Vol:285, ISSN:0021-9258, Pages:8743-8758

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