Imperial College London
Portrait Picture

Prof Rob Law

Faculty of Natural Sciences, Department of Chemistry

Professor of Biological Materials
 
 
 
//

Contact

 

+44 (0)20 7594 5860r.law Website

 
 
//

Location

 

207GMolecular Sciences Research HubWhite City Campus

//

Summary

 

Publications

Publication Type
Year
to

164 results found

Carreras P, Elani Y, Law R, Brooks N, Seddon J, Ceset al., 2014, A droplet trapping microfluidic device for the study of mass-transport across droplet interface bilayers, MicroTAS 2014

Conference paper

Carreras P, Law RV, Brooks NJ, Seddon JM, Ces Oet al., 2014, Microfluidic generation of droplet interface bilayer networks incorporating real-time size sorting in linear and non-linear configurations, Biomicrofluidics, Vol: 8, ISSN: 1932-1058

In this study, a novel droplet based microfluidic method for the generation of different sized droplet interface bilayers is reported. A microfluidic platform was designed, which allows the generation and packing of picoliter lipid coated water droplets. Droplets were generated by hydrodynamic focusing coupled with selective transport along grooves according to their size. A trapping structure at the end of the groove and a fine control of the flow pressures allowed for the droplets to be successfully trapped and aligned on demand. This technology facilitates the fine control of droplet size production as well as the generation of extended networks from a variety of lipids including 1,2-diphytanoyl-sn-glycero-3- phosphocholine and 1,2-dioleoyl-sn-glycero-3-phosphocholine in linear and non- linear configurations, which is vital to the application of Droplet Interface Bilayers to biological network construction on-chip.

Journal article

Ces O, Seddon J, Law R, Brooks N, Templer Ret al., 2014, Novel Insights into the Mechanistic Routes of Lyotropic Phase Transitions, Publisher: INT UNION CRYSTALLOGRAPHY, Pages: C1187-C1187, ISSN: 2053-2733

Conference paper

Casey D, Charalambous K, Gee A, Law RV, Ces Oet al., 2014, Amphiphilic drug interactions with model cellular membranes are influenced by lipid chain-melting temperature, JOURNAL OF THE ROYAL SOCIETY INTERFACE, Vol: 11, ISSN: 1742-5689

Journal article

Karpukhina N, Hill RG, Law RV, 2014, Crystallisation in oxide glasses - a tutorial review, CHEMICAL SOCIETY REVIEWS, Vol: 43, Pages: 2174-2186, ISSN: 0306-0012

Journal article

Miller D, Booth PJ, Seddon JM, Templer RH, Law RV, Woscholski R, Ces O, Barter LMCet al., 2013, Protocell design through modular compartmentalization, JOURNAL OF THE ROYAL SOCIETY INTERFACE, Vol: 10, ISSN: 1742-5689

Journal article

Elani Y, Gee A, Law RV, Ces Oet al., 2013, Manufacturing vesicles with internal bilayer partitions: a novel unit for synthetic biology, 9th European-Biophysical-Societies-Association Congress, Publisher: SPRINGER, Pages: S55-S55, ISSN: 0175-7571

Conference paper

Tyler AII, Shearman GC, Parsons ES, Barriga HMG, Templer RH, Ces O, Brooks NJ, Law RV, Seddon JMet al., 2013, Tuning curvature in inverse micellar and bicontinuous cubic phases, 9th European-Biophysical-Societies-Association Congress, Publisher: SPRINGER, Pages: S140-S140, ISSN: 0175-7571

Conference paper

Brooks N, Barriga H, McCarthy N, Purushothaman S, Seddon J, Ces O, Law Ret al., 2013, Dynamic membrane structures at high pressure, 9th European-Biophysical-Societies-Association Congress, Publisher: SPRINGER, Pages: S118-S118, ISSN: 0175-7571

Conference paper

Karpukhina N, Abo-Mosallam HA, Hill RG, Law RVet al., 2013, Effect of Sodium, potassium and zinc substitutions in lithium disilicate glass and glass-ceramics, International Conference on the Chemistry of Glasses and Glass-Forming Melts (Lomonosov Conference), Publisher: SOC GLASS TECHNOLOGY, Pages: 76-83, ISSN: 1753-3562

Conference paper

Brauer DS, Karpukhina N, Kedia G, Bhat A, Law RV, Radecka I, Hill RGet al., 2013, Bactericidal strontium-releasing injectable bone cements based on bioactive glasses, JOURNAL OF THE ROYAL SOCIETY INTERFACE, Vol: 10, ISSN: 1742-5689

Journal article

Elani Y, Gee A, Law RV, Ces Oet al., 2013, Engineering multi-compartment vesicle networks, CHEMICAL SCIENCE, Vol: 4, Pages: 3332-3338, ISSN: 2041-6520

Journal article

Zainuddin N, Karpukhina N, Law RV, Hill RGet al., 2012, Characterisation of a remineralising Glass Carbomer® ionomer cement by MAS-NMR Spectroscopy, DENTAL MATERIALS, Vol: 28, Pages: 1051-1058, ISSN: 0109-5641

Journal article

Fredholm YC, Karpukhina N, Brauer DS, Jones JR, Law RV, Hill RGet al., 2012, Influence of strontium for calcium substitution in bioactive glasses on degradation, ion release and apatite formation, JOURNAL OF THE ROYAL SOCIETY INTERFACE, Vol: 9, Pages: 880-889, ISSN: 1742-5689

Journal article

Charalambous K, Booth PJ, Woscholski R, Seddon JM, Templer RH, Law RV, Barter LMC, Ces Oet al., 2012, Engineering <i>de Novo</i> Membrane-Mediated Protein-Protein Communication Networks, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, Vol: 134, Pages: 5746-5749, ISSN: 0002-7863

Journal article

Fujikura K, Karpukhina N, Kasuga T, Brauer DS, Hill RG, Law RVet al., 2012, Influence of strontium substitution on structure and crystallisation of Bioglass® 45S5, JOURNAL OF MATERIALS CHEMISTRY, Vol: 22, Pages: 7395-7402, ISSN: 0959-9428

Journal article

Fujikura K, Obata A, Lin S, Jones JR, Law RV, Kasuga Tet al., 2012, Preparation of Electrospun Poly(Lactic Acid)-Based Hybrids Containing Siloxane-Doped Vaterite Particles for Bone Regeneration, JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION, Vol: 23, Pages: 1369-1380, ISSN: 0920-5063

Journal article

Aliev AE, Law RV, 2012, Solid state NMR spectroscopy, NUCLEAR MAGNETIC RESONANCE, VOL 41, Editors: KamienskaTrela, Wojcik, Publisher: ROYAL SOC CHEMISTRY, Pages: 244-289

Book chapter

Shaw KP, Brooks NJ, Clarke JA, Ces O, Seddon JM, Law RVet al., 2012, Pressure – temperature phase behaviour of natural sphingomyelin extracts, Soft Matter, Vol: 8, Pages: 1070-1078

Sphingomyelin is the only sphingolipid occurring naturally in mammalian cells and can form up to 50% of the total phospholipid content of the myelin sheath which surrounds nerves. Having predominantly long, saturated acyl chains, it has a relatively high chain melting temperature and has been strongly associated with formation of lipid microdomains. Here, the lyotropic phase behaviour of sphingomyelin from three different natural sources (bovine brain, egg yolk and milk) in excess water is studied as a function of temperature and pressure by small- and wide-angle X-ray scattering, and solid state NMR. The different hydrocarbon chain length distributions of the three lipid extracts results in significant differences in their gel phase structure; both the bovine brain and egg yolk sphingomyelins can form a ripple gel phase but milk sphingomyelin forms an interdigitated gel phase due to the high degree of chain mismatch in its longer hydrocarbon chain components.

Journal article

O'Donnell MD, Hill RG, Karpukhina N, Law RVet al., 2011, Real time neutron diffraction and NMR of the Empress II glass-ceramic system, DENTAL MATERIALS, Vol: 27, Pages: 990-996, ISSN: 0109-5641

Journal article

Shearman GC, Brooks NJ, Tiddy GJT, Sztucki M, Templer RH, Law RV, Ces O, Seddon JMet al., 2011, A lyotropic inverse ribbon phase in a branched-chain polyoxyethylene surfactant: pressure effects, SOFT MATTER, Vol: 7, Pages: 4386-4390, ISSN: 1744-683X

Journal article

Aliev AE, Law RV, 2011, Solid state NMR spectroscopy, NUCLEAR MAGNETIC RESONANCE, VOL 40, Editors: KamienskaTrela, Publisher: ROYAL SOC CHEMISTRY, Pages: 254-310

Book chapter

Tyler AII, Shearman GC, Brooks NJ, Delacroix H, Law RV, Templer RH, Ces O, Seddon JMet al., 2011, Hydrostatic pressure effects on a hydrated lipid inverse micellar <i>Fd</i>3<i>m</i> cubic phase, PHYSICAL CHEMISTRY CHEMICAL PHYSICS, Vol: 13, Pages: 3033-3038, ISSN: 1463-9076

Journal article

Hill RG, O'Donnell MD, Law RV, Karpukhina N, Cochrane B, Tulyaganov DUet al., 2010, The early stages of nucleation and crystallisation of an apatite glass-ceramic: Evidence for nano-scale crystallisation, 9th International Symposium on Crystallization in Glasses and Liquids, Publisher: ELSEVIER SCIENCE BV, Pages: 2935-2941, ISSN: 0022-3093

Conference paper

Brauer DS, Karpukhina N, Law RV, Hill RGet al., 2010, Effect of TiO<sub>2</sub> addition on structure, solubility and crystallisation of phosphate invert glasses for biomedical applications, 12th International Conference on the Physics of Non-Crystalline Solids (PNCS12), Publisher: ELSEVIER SCIENCE BV, Pages: 2626-2633, ISSN: 0022-3093

Conference paper

O'Donnell MD, Karpukhina N, Calver AI, Law RV, Bubb N, Stamboulis A, Hill RGet al., 2010, Real time neutron diffraction and solid state NMR of high strength apatite-mullite glass ceramic, 12th International Conference on the Physics of Non-Crystalline Solids (PNCS12), Publisher: ELSEVIER SCIENCE BV, Pages: 2693-2698, ISSN: 0022-3093

Conference paper

Fredholm YC, Karpukhina N, Law RV, Hill RGet al., 2010, Strontium containing bioactive glasses: Glass structure and physical properties, 12th International Conference on the Physics of Non-Crystalline Solids (PNCS12), Publisher: ELSEVIER, Pages: 2546-2551, ISSN: 0022-3093

Conference paper

Brauer DS, Karpukhina N, O'Donnell MD, Law RV, Hill RGet al., 2010, Fluoride-containing bioactive glasses: Effect of glass design and structure on degradation, pH and apatite formation in simulated body fluid, ACTA BIOMATERIALIA, Vol: 6, Pages: 3275-3282, ISSN: 1742-7061

Journal article

Munhoz T, Karpukhina N, Hill RG, Law RV, De Almeida LHet al., 2010, Setting of commercial glass ionomer cement Fuji IX by <SUP>27</SUP>Al and <SUP>19</SUP>F MAS-NMR, JOURNAL OF DENTISTRY, Vol: 38, Pages: 325-330, ISSN: 0300-5712

Journal article

Watts SJ, Hill RG, O'Donnell MD, Law RVet al., 2010, Influence of magnesia on the structure and properties of bioactive glasses, JOURNAL OF NON-CRYSTALLINE SOLIDS, Vol: 356, Pages: 517-524, ISSN: 0022-3093

Journal article

This data is extracted from the Web of Science and reproduced under a licence from Thomson Reuters. You may not copy or re-distribute this data in whole or in part without the written consent of the Science business of Thomson Reuters.

Request URL: http://wlsprd.imperial.ac.uk:80/respub/WEB-INF/jsp/search-html.jsp Request URI: /respub/WEB-INF/jsp/search-html.jsp Query String: id=00159838&limit=30&person=true&page=3&respub-action=search.html