Imperial College London
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DrRaviParekh

Faculty of Medicine, School of Public Health

Director, Medical Education Innovation and Research Centre
 
 
 
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Contact

 

r.parekh

 
 
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Location

 

Postgraduate CentreReynolds BuildingCharing Cross Campus

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Summary

 

Publications

Citation

BibTex format

@article{Parekh:2014:10.1136/bcr-2013-203502,
author = {Parekh, R and Fattah, Z and Sahota, D and Colaco, B},
doi = {10.1136/bcr-2013-203502},
journal = {BMJ Case Rep},
title = {Clozapine induced tubulointerstitial nephritis in a patient with paranoid schizophrenia.},
url = {http://dx.doi.org/10.1136/bcr-2013-203502},
volume = {2014},
year = {2014}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - We describe the development of tubulointerstitial nephritis after starting clozapine therapy in a patient with treatment-resistant schizophrenia. A 54-year-old mixed-race patient with a longstanding history of paranoid schizophrenia was started on the antipsychotic clozapine. Two months after starting clozapine he developed fevers, cough and acute renal failure which initially responded to 7days of prednisolone but recurred after completing the steroid course. Renal biopsy confirmed acute tubulointerstitial nephritis and he was started on a course of steroids with renal recovery in 72h. Clozapine was later stopped. This case highlights a serious and potential life-threatening complication of an important antipsychotic used in treatment-resistant schizophrenia.
AU  - Parekh,R
AU  - Fattah,Z
AU  - Sahota,D
AU  - Colaco,B
DO  - 10.1136/bcr-2013-203502
PY  - 2014///
TI  - Clozapine induced tubulointerstitial nephritis in a patient with paranoid schizophrenia.
T2  - BMJ Case Rep
UR  - http://dx.doi.org/10.1136/bcr-2013-203502
UR  - https://www.ncbi.nlm.nih.gov/pubmed/24849641
VL  - 2014
ER  -
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