Summary
I am a research associate working with Dr Nelofer Syed on cancer cell metabolism and response to chemotherapy. I am particularly interested in the role of NAD metabolism in chemosensitivity in glioblastoma multiforme.
I completed my PhD at Imperial College London in July 2018. I received a distinction in the Masters of Biomedical Research (Personalised Healthcare stream) from Imperial College London, England, in 2014. During my masters I completed two research projects, the first with Dr Hector Keun, looking at the role of metabolic pathways in platinum sensitivity in breast and ovarian cancer. My second project was spent investigating the role of oxygen availability on mesenchymal stem cell metabolism, under the supervision of Professor Sara Rankin.
I attained a Bachelor of Science with Honours in Medical Sciences (1st class) at Exeter University, England, in 2013. Whilst there I completed a professional training year with Professor Timothy Frayling of the genetics of complex traits group, primarily focusing on the role of common genetic variants in diabetes and obesity.
Publications
Journals
Perryman R, Renziehausen A, Shaye H, et al., 2023, Inhibition of the angiotensin II type 2 receptor AT2R is a novel therapeutic strategy for glioblastoma, Proceedings of the National Academy of Sciences of Usa, Vol:119, ISSN:0027-8424
Hajji N, Garcia-Revilla J, Sarmiento Soto M, et al., 2022, Arginine deprivation alters microglia polarity and synergises with radiation to eradicate non arginine auxotrophic glioblastoma tumors, Journal of Clinical Investigation, Vol:132, ISSN:0021-9738, Pages:1-19