Imperial College London


Faculty of MedicineSchool of Public Health

Honorary Research Fellow



+44 (0)20 7594 8974r.peters




Stadium HouseWhite City Campus





Dr Peters current work is focused on use of different antihypertensives, frailty and risk and benefit of treatment in the very elderly.

Between 2010 and 2012 Dr Peters was part of the core team setting up and developing the Imperial Clinical Trials Unit (ICTU). ICTU was launched in 2010 and is a fully UKCRC registered trials unit.

Prior to 2010 she led the multinational HYpertension in the Very Elderly Trial Cognitve function (HYVET-COG) study and co-ordinated the main Hypertension in the Very Elderly [HYVET] trial. HYVET was an Imperial sponsored multinational double blind RCT which was rated ‘Trial of the year’ by  the Society for Clinical Trials and an exceptional landmark in medicine(F1000) in 2008. The HYVET trial results have changed global guidelines for the use of antihypertensive treatment in older adults (>=80 years).

Research interests include risk factors for dementia, particularly cardiovascular risk factors and potential interventions to ameliorate or prevent cognitive decline and dementia.



Peters R, Dodge HH, James S, et al., 2021, The epidemiology is promising, but the trial evidence is weak. Why pharmacological dementia risk reduction trials haven't lived up to expectations, and where do we go from here?, Alzheimers & Dementia, ISSN:1552-5260

de Heus RAA, Tzourio C, Lee EJL, et al., 2021, Association Between Blood Pressure Variability With Dementia and Cognitive Impairment: A Systematic Review and Meta-Analysis, Hypertension, Vol:78, ISSN:0194-911X, Pages:1478-1489

Stephen R, Barbera M, Peters R, et al., 2021, Development of the First WHO Guidelines for Risk Reduction of Cognitive Decline and Dementia: Lessons Learned and Future Directions, Frontiers in Neurology, Vol:12, ISSN:1664-2295

Kenning G, Ee N, Xu Y, et al., 2021, Intergenerational Practice in the Community-What Does the Community Think?, Social Sciences-basel, Vol:10

Jicha GA, Abner EL, Arnold SE, et al., 2021, Committee on High-quality Alzheimer's Disease Studies (CHADS) consensus report, Alzheimers & Dementia, ISSN:1552-5260

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