Publications
178 results found
Antikainen RL, Kastarinen MJ, Jousilahti P, et al., 2010, Despite evidence-based guidelines, systolic blood pressure remains inadequately controlled in older hypertensive adults, JOURNAL OF HUMAN HYPERTENSION, Vol: 24, Pages: 439-446, ISSN: 0950-9240
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- Citations: 16
Peters R, Poulter R, Beckett N, et al., 2009, Cardiovascular and biochemical risk factors for incident dementia in the Hypertension in the Very Elderly Trial, JOURNAL OF HYPERTENSION, Vol: 27, Pages: 2055-2062, ISSN: 0263-6352
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- Citations: 48
Peters R, 2009, Antihypertensive Treatment After Diagnosis of Alzheimer's Disease, AMERICAN JOURNAL OF HYPERTENSION, Vol: 22, Pages: 1031-1031, ISSN: 0895-7061
Peters R, Beckett N, Geneva M, et al., 2009, Sociodemographic and lifestyle risk factors for incident dementia and cognitive decline in the HYVET*, AGE AND AGEING, Vol: 38, Pages: 521-527, ISSN: 0002-0729
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- Citations: 27
Peters R, Beckett N, 2009, Hypertension, dementia, and antihypertensive treatment: Implications for the very elderly, CURRENT HYPERTENSION REPORTS, Vol: 11, Pages: 277-282, ISSN: 1522-6417
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- Citations: 27
Beckett NS, Peters R, Potter J, et al., 2009, ORTHOSTATIC HYPOTENSION AS A PREDICTOR OF MORTALITY IN VERY ELDERLY HYPERTENSIVES: RESULTS FROM THE HYPERTENSION IN THE VERY ELDERLY TRIAL (HYVET), 19th European Meeting on Hypertension, Publisher: LIPPINCOTT WILLIAMS & WILKINS, Pages: S315-S316, ISSN: 0263-6352
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- Citations: 1
Peters R, Beckett N, Fletcher A, et al., 2009, BENEFIT BASED ON ACHIEVED BLOOD PRESSURE: RESULTS FROM THE HYPERTENSION IN THE VERY ELDERLY TRIAL (HYVET), 19th European Meeting on Hypertension, Publisher: LIPPINCOTT WILLIAMS & WILKINS, Pages: S168-S168, ISSN: 0263-6352
Peters R, Beckett NS, Burch L, et al., 2009, THE EFFECT OF TREATMENT BASED ON A DIURETIC (INDAPAMIDE)±AND ACE-INHIBITOR (PERINDOPRIL) ON INCIDENT FRACTURES IN A VERY ELDERLY HYPERTENSIVE POPULATION, DATA FROM THE HYPERTENSION IN THE VERY ELDERLY TRIAL (HYVET), 19th European Meeting on Hypertension, Publisher: LIPPINCOTT WILLIAMS & WILKINS, Pages: S272-S272, ISSN: 0263-6352
Antikainen RL, Beckett N, Peters R, et al., 2009, DETERMINANTS OF ELECTROCARDIOGRAPHIC LEFT VENTRICULAR HYPERTROPHY (ECG-LVH) AT BASELINE IN THE HYPERTENSION IN THE VERY ELDERLY TRIAL (HYVET), 19th European Meeting on Hypertension, Publisher: LIPPINCOTT WILLIAMS & WILKINS, Pages: S158-S158, ISSN: 0263-6352
Peters R, 2009, The prevention of dementia, INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY, Vol: 24, Pages: 452-458, ISSN: 0885-6230
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- Citations: 34
Peters R, Beckett N, Forette F, et al., 2009, Vascular risk factors and cognitive function among 3763 participants in the Hypertension in the Very Elderly Trial (HYVET): a cross-sectional analysis, INTERNATIONAL PSYCHOGERIATRICS, Vol: 21, Pages: 359-368, ISSN: 1041-6102
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- Citations: 12
Pinto E, Peters R, 2009, Literature Review of the Clock Drawing Test as a Tool for Cognitive Screening, DEMENTIA AND GERIATRIC COGNITIVE DISORDERS, Vol: 27, Pages: 201-213, ISSN: 1420-8008
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- Citations: 134
Bulpitt CJ, Beckett NS, Peters R, et al., 2009, Baseline characteristics of participants in the Hypertension in the Very Elderly Trial (HYVET), BLOOD PRESSURE, Vol: 18, Pages: 17-22
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- Citations: 5
Peters R, Poulter R, Warner J, et al., 2008, Smoking, dementia and cognitive decline in the elderly, a systematic review., BMC Geriatr, Vol: 8
BACKGROUND: Nicotine may aid reaction time, learning and memory, but smoking increases cardiovascular risk. Cardiovascular risk factors have been linked to increased risk of dementia. A previous meta-analysis found that current smokers were at higher risk of subsequent dementia, Alzheimer's disease, vascular dementia and cognitive decline. METHODS: In order to update and examine this further a systematic review and meta-analysis was carried out using different search and inclusion criteria, database selection and more recent publications. Both reviews were restricted to those aged 65 and over. RESULTS: The review reported here found a significantly increased risk of Alzheimer's disease with current smoking and a likely but not significantly increased risk of vascular dementia, dementia unspecified and cognitive decline. Neither review found clear relationships with former smoking. CONCLUSION: Current smoking increases risk of Alzheimer's disease and may increase risk of other dementias. This reinforces need for smoking cessation, particularly aged 65 and over. Nicotine alone needs further investigation.
Peters R, Pinto E, Beckett N, et al., 2008, Impact of depression on mortality and cardiovascular morbidity in very elderly hypertensives: data from The Hypertension In The Very Elderly Trial [HYVET], 13th Annual Meeting of the European-Council-for-Cardiovascular-Research, Publisher: LIPPINCOTT WILLIAMS & WILKINS, Pages: 761-761, ISSN: 0194-911X
Peters R, Peters J, Warner J, et al., 2008, Alcohol, dementia and cognitive decline in the elderly: a systematic review, AGE AND AGEING, Vol: 37, Pages: 505-512, ISSN: 0002-0729
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- Citations: 236
Liu L-S, Wang J-G, Ma S-P, et al., 2008, Characteristics of the Chinese subjects entered the Hypertension in the Very Elderly Trial, CHINESE MEDICAL JOURNAL, Vol: 121, Pages: 1509-1512, ISSN: 0366-6999
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- Citations: 9
Peters R, Burch L, Warner J, et al., 2008, Haemoglobin, anaemia, dementia and cognitive decline in the elderly, a systematic review., BMC Geriatr, Vol: 8
BACKGROUND: Anaemia may increase risk of dementia or cognitive decline. There is also evidence that high haemoglobin levels increase risk of stroke, and consequently possible cognitive impairment. The elderly are more at risk of developing dementia and are also more likely to suffer from anaemia, although there is relatively little longitudinal literature addressing this association. METHODS: To evaluate the evidence for any relationship between incident cognitive decline or dementia in the elderly and anaemia or haemoglobin level, we conducted a systematic review and meta-analyses of peer reviewed publications. Medline, Embase and PsychInfo were searched for English language publications between 1996 and 2006. Criteria for inclusion were longitudinal studies of subjects aged > or =65, with primary outcomes of incident dementia or cognitive decline. Other designs were excluded. RESULTS: Three papers were identified and only two were able to be combined into a meta-analysis. The pooled hazard ratio for these two studies was 1.94 (95 percent confidence intervals of 1.32-2.87) showing a significantly increased risk of incident dementia with anaemia. It was not possible to investigate the effect of higher levels of haemoglobin. CONCLUSION: Anaemia is one factor to bear in mind when evaluating risk of incident dementia. However, there are few data available and the studies were methodologically varied so a cautionary note needs to be sounded and our primary recommendation is that further robust research be carried out.
Peters R, Beckett N, Forette F, et al., 2008, Incident dementia and blood pressure lowering in the Hypertension in the Very Elderly Trial cognitive function assessment (HYVET-COG): a double-blind, placebo controlled trial, LANCET NEUROLOGY, Vol: 7, Pages: 683-689, ISSN: 1474-4422
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- Citations: 535
Antikainen RL, Beckett N, Kastarinen M, et al., 2008, Trends in blood pressure levels, hypertension prevalences, awareness and treatment in Finnish subject aged 60-74 years, 18th Scientific Meeting of the European-Society-of-Hypertension/22nd Scientific Meeting of the International-Society-of-Hypertension, Publisher: LIPPINCOTT WILLIAMS & WILKINS, Pages: S117-S117, ISSN: 0263-6352
Beckett NS, Peters R, Fletcher AE, et al., 2008, Treatment of hypertension in patients 80 years of age or older, NEW ENGLAND JOURNAL OF MEDICINE, Vol: 358, Pages: 1887-1898, ISSN: 0028-4793
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- Citations: 2081
Beckett N, Peters R, Bulpitt C, 2008, HYVET The hypertension in the very elderly trial, Publisher: Sherborne Gibbs Limited, ISBN: 978-1-905036-12-7
Peters R, Pinto EM, 2008, Predictive Value of the Clock Drawing Test A Review of the Literature, DEMENTIA AND GERIATRIC COGNITIVE DISORDERS, Vol: 26, Pages: 351-355, ISSN: 1420-8008
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- Citations: 29
Peters R, Martin-Marero C, Pinto E, et al., 2007, Hypertension in the very elderly, Aging Health, Vol: 3, Pages: 517-525, ISSN: 1745-509X
The world population is aging and disorders that are more prevalent in the elderly are of increasing importance. Hypertension falls into this category and has been linked to many adverse outcomes from stroke to mortality and dementia. Antihypertensive treatment has been shown to be successful in younger age groups but in those aged 80 years and over its benefits are not yet proven, and the risks and benefits of hypertension and antihypertensive treatment are unclear. Given this, it is useful to examine hypertension in the very elderly, the epidemiology, the likely impact of hypertension in this population, both physical and mental, and the as yet unclear issue of treatment. An ongoing, randomized, controlled trial in this age group will aid resolution of these issues and our understanding of this very elderly group. © 2007 Future Medicine Ltd.
Banya W, Beckett N, Peters R, et al., 2007, Very elderly Chinese hypertensives may have better renal function than Europeans - Baseline data from the hypertension in the very elderly trial, 17th European Meeting on Hypertension, Publisher: LIPPINCOTT WILLIAMS & WILKINS, Pages: S68-S68, ISSN: 0263-6352
Peters R, Beckett N, Comsa M, et al., 2007, Diabetes and cognition in very elderly hypertensives, 17th European Meeting on Hypertension, Publisher: LIPPINCOTT WILLIAMS & WILKINS, Pages: S138-S139, ISSN: 0263-6352
N Beckett, R Peters, 2007, Diagnosis and treatment of stable angina in older people, Prescriber, Vol: 18, Pages: 38-46
Bulpitt CJ, Peters R, Staessen JA, et al., 2006, Fracture risk and the use of a diuretic (indapamide sr) ± perindopril:: a substudy of the Hypertension in the Very Elderly Trial (HYVET), TRIALS, Vol: 7
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- Citations: 13
Peters R, Beckett N, Wang J, et al., 2006, Characteristics of very elderly hypertensive patients with atrial fibrillation [AF] in the hypertension in the very elderly trial (HYVET), 21sth Scientific Meeting of the International-Society-of-Hypertension/5th Asian-Pacific Congress of Hypertension/29th Annual Scientific Meeting of the Japanese-Society-of-Hypertension, Publisher: LIPPINCOTT WILLIAMS & WILKINS, Pages: 51-51, ISSN: 0263-6352
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- Citations: 1
Beckett N, Peters R, Liu L, et al., 2006, Prevalence of atrial fibrillation (AF) in very elderly hypertensives: results from the hypertension in the very elderly trial (HYVET), 21sth Scientific Meeting of the International-Society-of-Hypertension/5th Asian-Pacific Congress of Hypertension/29th Annual Scientific Meeting of the Japanese-Society-of-Hypertension, Publisher: LIPPINCOTT WILLIAMS & WILKINS, Pages: 144-144, ISSN: 0263-6352
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