Publications
226 results found
Denny E, Schroter RC, 2003, Micro-mechanical computational modelling of lung alveoli, Biological Fluid Dynamics, Publisher: von Karman Institute, Belgium
Achaaban MR, Schroter RC, Forsling ML, et al., 2002, Effects of heat stress and dehydration on body water distribution in the dromedary camel (<i>Camelus dromedarius</i>), JOURNAL OF CAMEL PRACTICE AND RESEARCH, Vol: 9, Pages: 101-106, ISSN: 0971-6777
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- Citations: 1
Achaaban MR, Forsling ML, Schroter RC, et al., 2002, The neurohypophyseal hormone profiles in camel (<i>Camelus dromedarius</i>), JOURNAL OF CAMEL PRACTICE AND RESEARCH, Vol: 9, Pages: 115-119, ISSN: 0971-6777
Marlin DJ, Schroter RC, Cashman PMM, et al., 2002, Movements of thoracic and abdominal compartments during ventilation at rest and during exercise, Equine Veterinary Journal -Supplement, Pages: 384-390, ISSN: 0425-1644
Marlin DJ, Schroter RC, Cashman PMM, et al., 2002, Movements of thoracic and abdominal compartments during ventilation at rest and during exercise, Equine Veterinary Journal -Supplement, Pages: 384-390, ISSN: 0425-1644
The present investigation utilised simultaneous measurements of chest (Ch) and abdominal (Ab) circumferences and respiratory airflow to test the hypothesis that Ch circumferential expansion contributes proportionally little to tidal volume in the running Thoroughbred. During exercise, there were only small changes in Ch and Ab circumference and no increase with increasing tidal volume. At rest, walk and trot, the flow, Ch and Ab signals were in phase. However, during canter and gallop, the Ch and Ab changes were 180° out of phase with each other and both were out of phase with airflow. In contrast to exercise, increase in ventilation at rest achieved by administration of lobeline resulted in a 4–6-fold increase in tidal volume; large excursions of the chest were always in phase with airflow. Furthermore, 3 horses showed an increase in chest circumference, demonstrating that chest stiffness per se does not preclude chest circumferential expansion. In conclusion, in the absence of significant increases in either Ch or Ab expansion during running, elongation of the thoracoabdominal segment may be the main determinant of tidal volume.
Caro CG, Schroter RC, Watkins N, et al., 2002, Steady inspiratory flow in planar and non-planar models of human bronchial airways, PROCEEDINGS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES, Vol: 458, Pages: 791-809, ISSN: 1364-5021
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- Citations: 12
Schroter RC, Marlin DJ, 2002, Modelling the oxygen cost of transport in competitions over ground of variable slope, Equine Veterinary Journal -Supplement-, Pages: 397-401
Deaton CM, Marlin DJ, Roberts CA, et al., 2002, Antioxidant supplementation and pulmonary function at rest and exercise, Equine Vet J Suppl, Pages: 58-65
Antioxidants have been implicated in the reduction and prevention of oxidative stress during exercise. We hypothesised that a dietary supplement containing a mixture of natural antioxidants together with vitamins E, C and selenium, given for 4 weeks, would increase the systemic and pulmonary antioxidant capacity leading to a reduction in markers of oxidative damage and an improvement in pulmonary function during exercise. In 6 healthy horses studied, the antioxidant supplement significantly increased plasma concentrations of ascorbic acid (from mean +/- s.d. 16 +/- 7 to 23 +/- 4 micromol/l; P = 0.007) and alpha-tocopherol (from 10 +/- 3 to 14 +/- 3 micromol/l; P = 0.02) and increased the bronchoalveolar lavage pulmonary epithelial lining fluid (ELF) concentration of ascorbic acid compared to a placebo, but not significantly (2.0 +/- 0.9 mmol/l and 1.2 +/- 0.9 mmol/l, respectively; P>0.05). Alpha-tocopherol was not detected in ELF either before or after supplementation or exercise. The mean concentration of malondialdehyde (MDA) in ELF was lower following antioxidant supplementation compared to placebo and control periods, but not significantly. An intermittent exercise test consisting of 2 min at 70, 80 and 90% of the horses' individual maximum oxygen uptake, failed to induce significant systemic or pulmonary oxidative stress (based on the glutathione redox ratio (GRR) and the ascorbic acid redox ratio (ARR)) and lipid peroxidation (based on the concentration of thiobarbituric acid reactive substances in plasma and MDA in ELF) either for placebo or antioxidant treatments. There was a strong correlation between GRR and ARR in the pulmonary epithelial lining fluid (r = 0.89; P<0.0001). In healthy horses on a diet containing adequate levels of antioxidants, additional antioxidant supplementation has no apparent beneficial or detrimental effect on pulmonary function during moderate intensity exercise. The importance of antioxidant supplementation may only become a
Deaton CM, Marlin DJ, Smith N, et al., 2002, Antioxidant supplementation in horses affected by recurrent airway obstruction, Joint Nutrition Symposium
Marlin DJ, Schroter RC, Jones HA, et al., 2002, Quantitative and qualitative high-resolution pulmonary ventilation-perfusion imaging using simultaneous acquisition of Krypton and Tc-MAA in healthy and RAO affected horses, Comparative Veterinary Respiration Society
Marlin DJ, Deaton CM, Smith NC, et al., 2002, Systemic and pulmonary antioxidant status in equine recurrent airway obstruction, Joint Nutrition Symposium
Scott CM, Marlin DJ, Schroter RC, 2001, Quantification of the response of equine apocrine sweat glands to β<sub>2</sub>-adrenergic stimulation, EQUINE VETERINARY JOURNAL, Vol: 33, Pages: 605-612, ISSN: 0425-1644
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- Citations: 10
Marlin DJ, Schroter RC, White SL, et al., 2001, Recovery from transport and acclimatisation of competition horses in a hot humid environment, EQUINE VETERINARY JOURNAL, Vol: 33, Pages: 371-379, ISSN: 0425-1644
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- Citations: 12
Marlin DJ, Schroter RC, Mills PC, et al., 2001, Performance of acclimatized European horses in a modified one star (*) three-day event in heat and humidity, JOURNAL OF EQUINE VETERINARY SCIENCE, Vol: 21, Pages: 341-350, ISSN: 0737-0806
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- Citations: 2
Sera T, Hasegawa Y, Schroter RC, et al., 2001, Three dimensional analysis of small airways with micro-CT, Proc. ASME 2001 Bioengineering Conference, Pages: 461-462
Leeming AD, Denny E, Schroter RC, 2001, Modelling parenchymal elasticity and airflow in the alveolar ducts, Proc. ASME 2001 Bioengineering Conference, Pages: 87-88
Gefen A, Halpem P, Shiner RJ, et al., 2001, Analysis of mechanical stresses within the alveolar septa leading to pulmonary edema, Technology and Health Care, Vol: 9, Pages: 257-268, ISSN: 0928-7329
Fujioka H, Schroter RC, 2001, Numerical analysis of flow in non-planar bifurcating tubes, Proc. ASME 2001 Bioengineering Conference, Pages: 605-606
Marlin DJ, Roberts CA, Schroter RC, 2000, A review of current knowledge concerning Exercise Induced Pulmonary Haemorrhage in the horse, The Sport Horse Annual 2000, Wellingborough, Northamptonshire, UK, Publisher: British Horse Database Ltd.
Marlin DJ, Roberts CA, Schroter RC, et al., 2000, Respiratory responses of mature horses to intravenous lobeline bolus, Equine Veterinary Journal, Vol: 32, Pages: 200-207
Achaaban MR, Schroter RC, Forsling ML, et al., 2000, Salt balance in camels subjected to neat stress and water deprivation under two different environmental conditions, Journal of Camel Practice and Research, Vol: 7, Pages: 57-62
Physick-Sheard PW, Marlin DJ, Thornhill R, et al., 2000, Frequency domain analysis of heart rate variability in horses at rest and during exercise, Equine Veterinary Journal, Vol: 32, Pages: 253-262
Denny E, Schroter RC, 2000, Viscoelastic behavior of a lung alveolar duct model, Journal of Biomechanical Engineering-Transactions of the Asme, Vol: 122, Pages: 143-151
Caro CG, Schroter RC, Watkins N, et al., 2000, Steady inspiratory flow in planar and non-planar models of human bronchial airways, J. Physiol.
Scott CM, Marlin DJ, Schroter RC, 1999, Thermoregulation strategies during short term exercise at different intensities, Equine Vet.J., Vol: Suppl. 30, Pages: 356-361
Marlin DJ, Scott CM, Schroter RC, et al., 1999, Physiological responses of horses to a treadmill simulated speed and endurance test in high heat and humidity before and after humid heat acclimation, Equine Veterinary Journal, Vol: 31, Pages: 31-42
Marlin DJ, Schroter RC, Scott CM, et al., 1999, Sweating and skin temperature responses of anhidrotic and non-anhidrotic horses to intravenous adrenaline, Equine Vet.J., Vol: Suppl. 30, Pages: 362-369
Schroter RC, Leeming AD, Denny E, et al., 1999, Modelling impact-initiated wave transmission through lung parenchyma in relation to exercise-induced pulmonary haemorrhage, Equine Veterinary Journal, Vol: Suppl. 30, Pages: 34-38
Schroter RC, Leeming AD, Denny E, et al., 1999, Modelling impact-initiated wave transmission through lung parenchyma in relation to exercise-induced pulmonary haemorrhage, Equine Veterinary Journal, Vol: Suppl. 30, Pages: 34-38
Schroter RC, Marlin DJ, Denny E, 1998, Is exercised-induced pulmonary haemorrhage (EIPH) in horses caused by locomotory impact-induced trauma?, J PHYSIOL-LONDON, Vol: 507P, ISSN: 0022-3751
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