Imperial College London
Professor Richard Syms

ProfessorRichardSyms

Faculty of Engineering, Department of Electrical and Electronic Engineering

Professor
 
 
 
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Contact

 

+44 (0)20 7594 6203r.syms

 
 
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Location

 

702Electrical EngineeringSouth Kensington Campus

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Summary

 

Publications

Citation

BibTex format

@article{Kardoulaki:2015:10.1118/1.4908225,
author = {Kardoulaki, EM and Syms, RRA and Young, IR and Choonee, K and Rea, M and Gedroyc, WMW},
doi = {10.1118/1.4908225},
journal = {Medical Physics},
pages = {1389--1397},
title = {Optothermal profile of an ablation catheter with integrated microcoil for MR-thermometry during Nd:YAG laser interstitial thermal therapies of the liver-An in-vitro experimental and theoretical study},
url = {http://dx.doi.org/10.1118/1.4908225},
volume = {42},
year = {2015}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Purpose: Flexible microcoils integrated with ablation catheters can improve the temperature accuracyduring local MR-thermometry in Nd:YAG laser interstitial thermal therapies. Here, the authors areconcerned with obtaining a preliminary confirmation of the clinical utility of the modified catheter.They investigate whether the thin-film substrate and copper tracks of the printed coil inductor affectthe symmetry of the thermal profile, and hence of the lesion produced.Methods: Transmission spectroscopy in the near infrared was performed to test for the attenuationat 1064 nm through the 25 µm thick Kapton substrate of the microcoil. The radial transmissionprofile of an infrared high-power, light emitting diode with >80% normalized power at 1064 nmwas measured through a cross section of the modified applicator to assess the impact of the copperinductor on the optical profile. The measurements were performed in air, as well as with the applicatorsurrounded by two types of scattering media; crystals of NaCl and a layer of liver-mimicking gelphantom. A numerical model based on Huygens–Fresnel principle and finite element simulations,using a commercially available package (COMSOL Multiphysics), were employed to compare withthe optical measurements. The impact of the modified optical profile on the thermal symmetry wasassessed by examining the high resolution microcoil derived thermal maps from a Nd:YAG laserablation performed on a liver-mimicking gel phantom.Results: Less than 30% attenuation through the Kapton film was verified. Shadowing behind thecopper tracks was observed in air and the measured radial irradiation correlated well with the diffractionpattern calculated numerically using the Huygens–Fresnel principle. Both optical experimentsand simulations, demonstrate that shadowing is mitigated by the scattering properties of a turbidmedium. The microcoil derived thermal maps at the end of a Nd:YAG laser ablation performed on agel phantom in a 3 T s
AU  - Kardoulaki,EM
AU  - Syms,RRA
AU  - Young,IR
AU  - Choonee,K
AU  - Rea,M
AU  - Gedroyc,WMW
DO  - 10.1118/1.4908225
EP  - 1397
PY  - 2015///
SN  - 0094-2405
SP  - 1389
TI  - Optothermal profile of an ablation catheter with integrated microcoil for MR-thermometry during Nd:YAG laser interstitial thermal therapies of the liver-An in-vitro experimental and theoretical study
T2  - Medical Physics
UR  - http://dx.doi.org/10.1118/1.4908225
UR  - http://hdl.handle.net/10044/1/31292
VL  - 42
ER  -
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