Having studied biology (PhD in pharmacokinetics) I then completed an MSc at the London School of Hygiene and Tropical Medicine and thus became a medical statistician. It is in this role that I contribute to the substantial academic output of the department.
For a number of years the main research focus of the department has been Chronic Myeloid Leukaemia, and specifically its treatment with stem cell transplantation (SCT). I have been involved in many studies that have sought to identify prognostic factors associated with survival, disease relapse, transplant related mortality and graft versus host disease post SCT.
More recently, wider departmental interests have fostered collaborations with a number of colleagues studying the biological processes, as well as treatment options, for a variety of diseases, including Multiple Myeloma, Hodgkin’s Lymphoma, Dyskaratosis Congenita and Amyloidosis.
The sum of all these research studies has resulted in being an author or co-author in over 160 peer-reviewed publications in journals ranging from Nature Genetics and the Lancet, to the Journal of Clinical Oncology and Blood, to the British Journal of Haematology and Bone Marrow Transplantation.
I also provide teaching support in key areas of good research practice: A) Experimental study design, B.) Data collection, and C.) Appropriate statistical analysis. Using workshops and individual tuition, expert knowledge is shared not only with departmental researchers and undergraduate medical students, but also with the Europe wide haematological community as part of the remit of the Statistical Committee of the European Bone Marrow Transplant Registry, of which I am an active member.
Alongside (or in addition to) my scientific career, I have always had a strong interest in photography, and am delighted to be able to display a selection of my prints in the Department of Haematology in the Commonwealth Building at the Hammersmith Hospital. Some of these can also be viewed at www.rsimages.smugmug.com
et al., 2021, Clinical outcomes and the impact of prior oral anticoagulant use in patients with coronavirus disease 2019 admitted to hospitals in the UK - a multicentre observational study., Br J Haematol
et al., 2021, Single-cell profiling of human bone marrow progenitors reveals mechanisms of failing erythropoiesis in Diamond-Blackfan anemia., Sci Transl Med, Vol:13
et al., 2021, Fecal microbiota transplant mitigates adverse outcomes in patients colonized with multidrug-resistant organisms undergoing allogeneic hematopoietic cell transplantation, Frontiers in Cellular and Infection Microbiology, ISSN:2235-2988
et al., 2021, Diagnostic application of transcripts associated with antibody-mediated rejection in kidney transplant biopsies, Nephrology Dialysis Transplantation, ISSN:0931-0509
et al., 2021, GENE EXPRESSION ANALYSIS USING QRT-PCR IN THE DIAGNOSIS OF ANTIBODY-MEDIATED REJECTION IN RENAL TRANSPLANT BIOPSIES, WILEY, Pages:290-290, ISSN:0934-0874