Overview
Biophysical chemistry of lipid membranes
- Lipid homeostasis
- Membrane fusion
Chemical physics of lyotropic liquid crystals
- Phase behaviour, structure and energetics
- Phase transition kinetics
- Phase behaviour at high pressure
Collaborators
Professor Nigel Burroughs, University of Warwick, Modelling the immune synapse
Professor Calum Drummond, CSIRO, Melbourne and Sydney, Membrane protein crystallisation
Professor Paul O'Shea, University of Nottingham
Dr Oscar Ces, Chemistry, Imperial College London
Professor Roland Winter, University of Dortmund
Professor Paul French, Physics, Imperial College London
Dr Ian Gould, Chemistry, Imperial College London, Drug-lipid interactions
Professor Xiaodong Zhang, Medicine, Imperial College London, PspA - membrane interactions
Professor Martin Buck, Life Sciences, Imperial College London, PspA - membrane interactions
Dr Liming Ying, NHLI, Imperial College London
Professor George Attard, University of Southampton, Lipid homeostasis
Professor Paula Booth, University of Bristol, Membrane protein folding
Professor Dan Davis, Life Sciences, Imperial College London, Membrane organisation at the synapse
Dr Rumiana Dimova, Max Planck Institute for Colloids and Interfaces, Golm, Membrane fusion
Professor Tony Gee, GSK, Clinical Imaging Centre, Drug-membrane interactions
Professor David Klug, Chemistry, Imperial College London
Professor John Seddon, Chemistry, Imperial College London
Dr Adam Squires, University of Reading
Professor Ake Wieslander, Stockholm University
Dr Mauricio Barahona, Maths, Imperial College London
Professor Andrew de Mello, Imperial College London
Professor Nick Long, Chemistry, Imperial College London, PET ligand synthesis
Dr Sophia Yaliraki, Chemistry, Imperial College London, Modelling membrane binding
Professor Kim Parker, Bioengineering, Imperial College London, Vesicle mechanics
Dr Piers Gaffney, Chemical Engineering, Imperial College London, PI lipid synthesis
Dr Mark Neil, Physics, Imperial College London
Dr Rudiger Woscholski, Chemistry, Imperial College London, PI phosphatases
Research Staff
alumnus,DAS
alumnus,DJR
alumnus,DLM
alumnus,DMS
alumnus,DON
alumnus,DSC
alumnus,DXM
alumnus,MKH
current,DGS
current,DNB
current,MBG
current,MSP
Research Student Supervision
Allen,DS, Membrane protein folding
Alley,DS, Lipid homeostasis in A. Laidlawii
Barriga,H, Is the folding of CCR5 in different detergent-lipid systems dependent on lateral pressure?
Bate,P, MRes on non-specific drug binding
Casey,D, Non-specific binding of PET ligands
Castle,DS, Sensing bilayer pressures
Ces,DO, Pressure effects on lipid phase behaviour
Child,C, Bridging the In-Vivo, In-Vitro Divide in Non-Specific Binding
Clay,E, Chemical reactions at membrane interfaces
Conn,DC, Kinetics of lyotropic phase transitions
Curran,DR, Membrane protein folding
Duesing,DP, Pressure induced phase behaviour
Furse,S, Synthesis, curvature elasticity and biochemistry of PIP2 lipids
Heron,DA, CCT-lipid interactions effects of charge
Huang,DZ, PC/FA mixtures
Kaplinsky,J, Single cell proteomics
Khoo,DB, Studies of curvature elasticity
Knott,J, Single vesicle stress measurement
Kulkarni,C, Membrane protein crystallisation in bicotninuous cubic phases
Ling,R, MRes on non-sepcific drug binding
Macey,R, Drug non-specific binding studies
Madan,K, MSc on DOPE/DOPC/MO phase behaviour
Moriarty,DS, Biocompatible lipids
Mulet,DX, PI lipid phase behaviour and single cell manipulation
Roberts,DS, Di-chained oxyethylene surfactant phase behaviour
Sakya,DP, Epitaxial relationships in lyotropics
Sebai,DS, Non-specific binding of PET ligand
Sennoga,DC, In-cubo protein crystallisation
Serrano,J, MRes on the sigma-1 receptor
Shearman,DG, Instabilities in surfactant phase behaviour
Squires,DA, Energetics and kinetics of lyotropic phase transitions
Swain,DG, MRes on membrane toxin interactions
Tang,D, Kinetics of lyotropic phase transitions
Turner,C, Quantitative SNARE fusion studies
Warrender,DN, FA/PC phase behaviour
Yates,DC, Lyotropic polymers
Zeb,DN, Glycolipid phase behaviour