Imperial College London


Faculty of MedicineNational Heart & Lung Institute

Research Associate







Mint WingSt Mary's Campus





Ryan Thwaites is a Research Associate within the Department of Respiratory Medicine of the National Heart and Lung Institute, Imperial College London. Ryan obtained his PhD in 2015 in the field of innate immunology from the Brighton and Sussex Medical School, University of Sussex. Following on from this work, he joined Professor Peter Openshaw and Professor Trevor Hansel at the NHLI.

His research continues to investigate the activity of the innate immune system in human disease, particularly during the anti-viral immune response. This work uses non-infectious human models of innate immune activation (such as Toll-like receptor agonists), experimental human infection models and natural infection. In addition to these biological interests, Ryan's work has developed non-invasive techniques for sampling the airways of infants during viral infections.



Wiseman DJ, Thwaites RS, Openshaw PJM, 2020, A new role for CXCL4 in RSV disease., American Journal of Respiratory and Critical Care Medicine, ISSN:1073-449X

Thwaites RS, Unterberger S, Chamberlain G, et al., 2020, TLR1/2 and 5 induce elevated cytokine levels from rheumatoid arthritis monocytes independent of ACPA or RF autoantibody status., Rheumatology, ISSN:1462-0324

Sancho Shimizu V, 2020, A rare mutation in SPLUNC1 underlies meningococcal disease affecting bacterial adherence and invasion, Clinical Infectious Diseases, Vol:70, ISSN:1058-4838, Pages:2045-2053

Dunning J, Thwaites RS, Openshaw PJM, 2020, Seasonal and pandemic influenza: 100 years of progress, still much to learn, Mucosal Immunology, Vol:, ISSN:1935-3456, Pages:566-573

Wiseman DJ, Thwaites RS, Drysdale SB, et al., 2020, Immunological and inflammatory biomarkers of susceptibility and severity in adult respiratory syncytial virus infections., Journal of Infectious Diseases, ISSN:0022-1899

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