Ryan Thwaites is a Research Associate within the Department of Respiratory Medicine of the National Heart and Lung Institute, Imperial College London. Ryan obtained his PhD in 2015 in the field of innate immunology from the Brighton and Sussex Medical School, University of Sussex. Following on from this work, he joined Professor Peter Openshaw and Professor Trevor Hansel at the NHLI.
His research continues to investigate the activity of the innate immune system in human disease, particularly during the anti-viral immune response. This work uses non-infectious human models of innate immune activation (such as Toll-like receptor agonists), experimental human infection models and natural infection. In addition to these biological interests, Ryan's work has developed non-invasive techniques for sampling the airways of infants during viral infections.
et al., 2021, Expression of sterile-α and armadillo motif in rheumatoid arthritis monocytes correlates with TLR2 induced IL-1β and disease activity., Rheumatology (oxford)
et al., 2021, Increased nasal mucosal interferon and CCL13 response to a TLR7/8 agonist in asthma and allergic rhinitis., Journal of Allergy and Clinical Immunology, Vol:147, ISSN:0091-6749, Pages:694-703.e12
et al., 2021, Development and validation of the ISARIC 4C Deterioration model for adults hospitalised with COVID-19: a prospective cohort study, The Lancet Respiratory Medicine, ISSN:2213-2600
et al., 2020, Simultaneous Viral Whole-Genome Sequencing and Differential Expression Profiling in Respiratory Syncytial Virus Infection of Infants, Journal of Infectious Diseases, Vol:222, ISSN:0022-1899, Pages:S666-S671