Imperial College London
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DrRyanThwaites

Faculty of Medicine, National Heart & Lung Institute

Lecturer in Respiratory Immunology
 
 
 
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r.thwaites

 
 
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Location

 

Respiratory InfectionsMedical SchoolSt Mary's Campus

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Summary

 

Publications

Citation

BibTex format

@article{Baumann:2021:10.1111/all.14645,
author = {Baumann, R and Untersmayr, E and Zissler, UM and Eyerich, S and Adcock, IM and Brockow, K and Biedermann, T and Ollert, M and Chaker, AM and Pfaar, O and Garn, H and Thwaites, RS and Togias, A and Kowalski, ML and Hansel, T and Jakwerth, C and Schmidt-Weber, CB},
doi = {10.1111/all.14645},
journal = {Allergy},
pages = {1010--1023},
title = {Non-invasive and minimally-invasive techniques for the diagnosis and management of allergic diseases.},
url = {http://dx.doi.org/10.1111/all.14645},
volume = {76},
year = {2021}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Allergic diseases of the (upper and lower) airways, the skin as well as the gastrointestinal tract, are on the rise, resulting in impaired quality of life, decreased productivity and increased healthcare costs. As allergic diseases are mostly tissue specific, local sampling methods for respective biomarkers offer the potential for increased sensitivity and specificity. Additionally, local sampling using non-invasive or minimally-invasive methods can be cost-effective and well tolerated, which may even be suitable for primary or home care sampling. Non- or minimally-invasive local sampling and diagnostics may enable a more thorough endotyping, may help to avoid under- or overdiagnosis, and may provide the possibility to approach precision prevention, due to early diagnosis of these local diseases even before they get systemically manifested and detectable. At the same time, dried blood samples may help to facilitate minimal-invasive primary or home care sampling for classical systemic diagnostic approaches. This EAACI position paper contains a thorough review of the various technologies in allergy diagnosis available on the market, which analytes or biomarkers are employed, and which samples or matrices can be used. Based on this assessment, EAACIs position is to drive these developments to efficiently identify allergy and possibly later also viral epidemics and take advantage of comprehensive knowledge to initiate preventions and treatments.
AU  - Baumann,R
AU  - Untersmayr,E
AU  - Zissler,UM
AU  - Eyerich,S
AU  - Adcock,IM
AU  - Brockow,K
AU  - Biedermann,T
AU  - Ollert,M
AU  - Chaker,AM
AU  - Pfaar,O
AU  - Garn,H
AU  - Thwaites,RS
AU  - Togias,A
AU  - Kowalski,ML
AU  - Hansel,T
AU  - Jakwerth,C
AU  - Schmidt-Weber,CB
DO  - 10.1111/all.14645
EP  - 1023
PY  - 2021///
SN  - 0105-4538
SP  - 1010
TI  - Non-invasive and minimally-invasive techniques for the diagnosis and management of allergic diseases.
T2  - Allergy
UR  - http://dx.doi.org/10.1111/all.14645
UR  - https://www.ncbi.nlm.nih.gov/pubmed/33128851
UR  - https://onlinelibrary.wiley.com/doi/10.1111/all.14645
UR  - http://hdl.handle.net/10044/1/83986
VL  - 76
ER  -
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