Imperial College London
Alternate

ProfessorRolandVeltkamp

Faculty of Medicine, Department of Brain Sciences

Professor of Neurology and Chair of Stroke Medicine
 
 
 
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Contact

 

r.veltkamp

 
 
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Location

 

3 East6East WingCharing Cross Campus

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Summary

 

Publications

Citation

BibTex format

@article{Weber:2022:10.1186/s42466-022-00215-7,
author = {Weber, R and Winezki, E and Katsanos, AH and Cueillette, M and Hajjar, K and Yamac, E and Veltkamp, R and Chapot, R},
doi = {10.1186/s42466-022-00215-7},
journal = {Neurological Research and Practice},
title = {Sex differences in etiology and short-term outcome in young ischemic stroke patients receiving mechanical thrombectomy},
url = {http://dx.doi.org/10.1186/s42466-022-00215-7},
volume = {4},
year = {2022}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - BACKGROUND: Although there are well known sex differences in older patients with ischemic stroke receiving acute reperfusion treatments, there is paucity of data in younger patients. METHODS: We investigated sex-related differences in clinical presentation, stroke etiology and short-term outcomes in consecutive young patients with acute ischemic stroke (AIS) below the age of 50 years receiving mechanical thrombectomy (MT) between January 2011 and May 2021 in a tertiary stroke center. RESULTS: We identified a total of 202 young ischemic stroke patients with MT, with 51% being female. Young female AIS patients were significantly younger (39 ± 8 vs. 43 ± 7 years, p < 0.001), and presented with a trend for more severe stroke on admission (median NIHSS 12 vs. 9, p = 0.065), compared to males, respectively. Young female AIS patients had higher rates of embolic strokes of determined or undetermined sources in the anterior circulation, while young male AIS patients suffered more often strokes of arterio-arterial embolism. Complete reperfusion (TICI score 3) was achieved significantly less often in young female AIS patients (69% vs. 83%, p = 0.006), and in-hospital mortality was 2-times higher (5% vs. 2%, p = 0.271) compared to males. CONCLUSIONS: Young female AIS patients receiving MT have higher rates of severe embolic strokes and less often complete reperfusion due to different occlusion sites and stroke etiology compared to males.
AU  - Weber,R
AU  - Winezki,E
AU  - Katsanos,AH
AU  - Cueillette,M
AU  - Hajjar,K
AU  - Yamac,E
AU  - Veltkamp,R
AU  - Chapot,R
DO  - 10.1186/s42466-022-00215-7
PY  - 2022///
SN  - 2524-3489
TI  - Sex differences in etiology and short-term outcome in young ischemic stroke patients receiving mechanical thrombectomy
T2  - Neurological Research and Practice
UR  - http://dx.doi.org/10.1186/s42466-022-00215-7
UR  - https://www.ncbi.nlm.nih.gov/pubmed/36244994
UR  - http://hdl.handle.net/10044/1/101348
VL  - 4
ER  -
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