Imperial College London

DrRobertWeinzierl

Faculty of Natural SciencesDepartment of Life Sciences

Reader in Molecular Biology
 
 
 
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Contact

 

+44 (0)20 7594 5236r.weinzierl

 
 
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Location

 

510Sir Alexander Fleming BuildingSouth Kensington Campus

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Summary

 

Collaborators

Zachary Burton, University of Michigan, 2010

Craig Kaplan, Texas A&M University, 2010

Maria Kireeva / Mikhail Kashlev, NCI-Frederick, Maryland, 2010

Gabor Terstyanszky / Tamas Kiss, University of Westminster, 2009

Tom Santangelo, Ohio State University, 2009

Ramesh Wigneshweraraj, Medicine, Imperial Collge London, 2008

Martin Buck, Life Sciences, Imperial College London, 2006

Peter Brick, Life Sciences, Imperial College London, 2003 - 2006

Peter Geiduschek, University of California - San Diego, 2003

Silvia Onesti, Imperial College London, 1998 - 2006

Guest Lectures

Transcriptional Dynamics, Evolution and Systems Biology, Michigan State University, 2011

Molecular Biology of Archaea” Symposium, University of Regensburg, 2011

The nanomechanical properties of the Bridge Helix domain control the rate of the nucleotide addition cycle, RNAP2010 - Structure, Function and Evolution of RNA Polymerases”. Harden Conference - Biochemical Society/Wellcome Trust, Hinxton Genome Campus, 2010

Robotic Dissection of the catalytic center of archaeal RNA polymerases, Biochemical Society Focused Meeting “Molecular Biology of the Archaea II”, Cambridge, Robinsom College, 2010

High-throughput structure/function dissection of the catalytic mechanism of RNA polymerase, Cancer Research UK, Clare Hall Laboratories, 2010

High-throughput structure/function dissection of the catalytic center of RNA polymerase, FASEB Conference "Prokaryotic Transcript", Saxton Falls, Vermont, 2009

The mechanistic properties of the catalytic center of RNA polymerase, PAA laboratory Automation Conference, Hinxton Genome Campus, 2009

High-throughput structure/function dissection of the catalytic center of RNA polymerase, University of Manchester, Faculty of Life Sciences, 2009

The mechanistic properties of the catalytic center of RNA polymerase, RNA Polymerase Workshop, Bristol, 2009

High-throughput structure/function dissection of the catalytic center of RNA polymerase, Bichemical Society Meeting "Machines on genes: enzymes that make, break, and move DNA and RNA", Cambridge Robinson College, 2009

High-throughput structure/function dissection of the catalytic center of RNA polymerase, Conference: The Regulation and Transcription of Eukaryotic Genes, Glen Cove Conference Center - New York, 2009

Bridge Helix/Trigger Loop residues critical for controlling the catalytic rate of archaeal RNA polymerase, RNA Polymerase Workshop, York, 2008

Functional dissection of archaeal RNA polymerase using novel robotic approaches, Extremophiles 2008, Capetown, 2008

Dissection of the archaeal transcriptional machinery using high-throughput robotics, University College London, 2007

Analysis of functional domains of RNA polymerase with robotic methods, Thermophiles 2007, University of Bergen, 2007

Analysis of functional domains of RNA polymerase with robotic methods, RNA Polymerase Workshop, 2007

Dissection of the archaeal transcriptional machinery using high-throughput robotics, University of Regensburg, 2007

The archaeal transcriptional machinery: new insights into initiation mechanisms, RNA Polymerase Workshop, Birmingham, 2006

Functional dissection of the archaeal transcriptional machinery using high-throughput robotics, Extremophiles 2006, Brest, 2006

The archaeal transcriptional machinery: new insights into initiation mechanisms, Molecular Biology of Archaea, Newcastle, 2006

High-throughput robotics for studying gene expression systems, EMBL Eukaryotic Transcription Meeting, EMBL, Heidelberg, 2006

Direct modulation of archaeal RNAP core functions by basal transcription factors, Biochemical Society Annual Symposium "Transcription UK 2005", 2005

The archaeal transcriptional machinery, University of Bristol, 2005

Functional dissection of the archaeal transcriptional machinery, FASEB Conference "Prokaryotic Transcription", Saxton Falls, Vermont, 2003

Research Student Supervision

Aligianni,S

Carney,H, Mutagenesis and functional analysis of the ‘lid’ domain of RNA polymerase

Nottebaum,S, In vitro assembly of recombinant archaeal RNA polymerase

Tan,L, Functional analysis of Methanocaldococcus jannaschii RNA polymerase A’ Bridge Helix using a fully automated high-throughput robotic system

Vengrova,S

Wiesler,S, High-resolution mutagenesis of the linker domain of archaeal basal transcription factor TFIIB