Collaborators
Zachary Burton, University of Michigan, 2010
Craig Kaplan, Texas A&M University, 2010
Maria Kireeva / Mikhail Kashlev, NCI-Frederick, Maryland, 2010
Gabor Terstyanszky / Tamas Kiss, University of Westminster, 2009
Tom Santangelo, Ohio State University, 2009
Ramesh Wigneshweraraj, Medicine, Imperial Collge London, 2008
Martin Buck, Life Sciences, Imperial College London, 2006
Peter Brick, Life Sciences, Imperial College London, 2003 - 2006
Peter Geiduschek, University of California - San Diego, 2003
Silvia Onesti, Imperial College London, 1998 - 2006
Guest Lectures
Transcriptional Dynamics, Evolution and Systems Biology, Michigan State University, 2011
Molecular Biology of Archaea” Symposium, University of Regensburg, 2011
The nanomechanical properties of the Bridge Helix domain control the rate of the nucleotide addition cycle, RNAP2010 - Structure, Function and Evolution of RNA Polymerases”. Harden Conference - Biochemical Society/Wellcome Trust, Hinxton Genome Campus, 2010
Robotic Dissection of the catalytic center of archaeal RNA polymerases, Biochemical Society Focused Meeting “Molecular Biology of the Archaea II”, Cambridge, Robinsom College, 2010
High-throughput structure/function dissection of the catalytic mechanism of RNA polymerase, Cancer Research UK, Clare Hall Laboratories, 2010
High-throughput structure/function dissection of the catalytic center of RNA polymerase, FASEB Conference "Prokaryotic Transcript", Saxton Falls, Vermont, 2009
The mechanistic properties of the catalytic center of RNA polymerase, PAA laboratory Automation Conference, Hinxton Genome Campus, 2009
High-throughput structure/function dissection of the catalytic center of RNA polymerase, University of Manchester, Faculty of Life Sciences, 2009
The mechanistic properties of the catalytic center of RNA polymerase, RNA Polymerase Workshop, Bristol, 2009
High-throughput structure/function dissection of the catalytic center of RNA polymerase, Bichemical Society Meeting "Machines on genes: enzymes that make, break, and move DNA and RNA", Cambridge Robinson College, 2009
High-throughput structure/function dissection of the catalytic center of RNA polymerase, Conference: The Regulation and Transcription of Eukaryotic Genes, Glen Cove Conference Center - New York, 2009
Bridge Helix/Trigger Loop residues critical for controlling the catalytic rate of archaeal RNA polymerase, RNA Polymerase Workshop, York, 2008
Functional dissection of archaeal RNA polymerase using novel robotic approaches, Extremophiles 2008, Capetown, 2008
Dissection of the archaeal transcriptional machinery using high-throughput robotics, University College London, 2007
Analysis of functional domains of RNA polymerase with robotic methods, Thermophiles 2007, University of Bergen, 2007
Analysis of functional domains of RNA polymerase with robotic methods, RNA Polymerase Workshop, 2007
Dissection of the archaeal transcriptional machinery using high-throughput robotics, University of Regensburg, 2007
The archaeal transcriptional machinery: new insights into initiation mechanisms, RNA Polymerase Workshop, Birmingham, 2006
Functional dissection of the archaeal transcriptional machinery using high-throughput robotics, Extremophiles 2006, Brest, 2006
The archaeal transcriptional machinery: new insights into initiation mechanisms, Molecular Biology of Archaea, Newcastle, 2006
High-throughput robotics for studying gene expression systems, EMBL Eukaryotic Transcription Meeting, EMBL, Heidelberg, 2006
Direct modulation of archaeal RNAP core functions by basal transcription factors, Biochemical Society Annual Symposium "Transcription UK 2005", 2005
The archaeal transcriptional machinery, University of Bristol, 2005
Functional dissection of the archaeal transcriptional machinery, FASEB Conference "Prokaryotic Transcription", Saxton Falls, Vermont, 2003
Research Student Supervision
Aligianni,S
Carney,H, Mutagenesis and functional analysis of the ‘lid’ domain of RNA polymerase
Nottebaum,S, In vitro assembly of recombinant archaeal RNA polymerase
Tan,L, Functional analysis of Methanocaldococcus jannaschii RNA polymerase A’ Bridge Helix using a fully automated high-throughput robotic system
Vengrova,S
Wiesler,S, High-resolution mutagenesis of the linker domain of archaeal basal transcription factor TFIIB