Imperial College London

Alex Bottle

Faculty of MedicineSchool of Public Health

Professor of Medical Statistics



+44 (0)20 7594 0913robert.bottle Website




3 Dorset Rise, London EC4Y 8ENCharing Cross HospitalCharing Cross Campus





Many of us rely on our local hospital, but how do we know if it's safe? Or better than the other one down the road? Every year we expect our healthcare system to treat more patients with more problems and to ever higher standards. We clearly need useable information on performance. The NHS benefits from huge but complex databases, and it's my job to help doctors, managers and patients make sense of them.

After secondment to the public inquiry into the crimes of GP Harold Shipman, I devised the statistical methodology behind the flagship information tool of our former commercial partners, Dr Foster. With my analysis, this tool correctly identified Mid Staffordshire NHS Trust as having unacceptably high death rates and was a trigger for the national regulator to investigate. My research today continues to measure and monitor the quality of healthcare in hospital and in the community for patients with chronic disease, such as heart failure, osteoarthritis and COPD, or multiple conditions, using databases such as HES and CPRD. My heart failure work was cited in the 2019 NHS Long-term Plan.

Among my teaching roles, I am the Academic Lead for my "Statistical Analysis with R for Public Health" specialisation that's live on Coursera and is part of Imperial's online Global MPH. As a consultant since 2016, I train the UK public sector on statistical thinking and data analysis to improve staff effectiveness. 

Please note that I am not taking on any more PhD students at the moment.



Jayasooriya N, Pollok RC, Blackwell J, et al., 2023, Adherence to 5-aminosalicylic acid maintenance treatment in young people with ulcerative colitis: a retrospective cohort study in primary care, British Journal of General Practice, ISSN:0960-1643

Williams R, Morris A, Gupta V, et al., 2023, Predictors of positive patient reported outcomes from ‘Early Intervention in Psychosis’ – a national cross-sectional study, Bmj Mental Health, Vol:26, ISSN:2755-9734, Pages:1-7

Ward JL, Harwood R, Kenny S, et al., 2023, Pediatric Hospitalizations and ICU Admissions Due to COVID-19 and Pediatric Inflammatory Multisystem Syndrome Temporally Associated With SARS-CoV-2 in England., Jama Pediatr, Vol:177, Pages:947-955

Lai HTM, Chang K, Sharabiani MTA, et al., 2023, Twenty-year trajectories of cardio-metabolic factors among people with type 2 diabetes by dementia status in England: a retrospective cohort study, European Journal of Epidemiology, Vol:38, ISSN:0393-2990, Pages:733-744

Pollok RC, Jayasooriya N, Baillie S, et al., 2023, Letter: delays to diagnosis of IBD-Challenges requiring a systematic approach. Authors' reply., Aliment Pharmacol Ther, Vol:57

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