Summary
Biography
| Date | Role |
|---|---|
| 2019 – |
Reader in Biomaterials Engineering, Department of Chemical Engineering, Imperial College London, UK |
| 2016 – 2019 | Senior Lecturer, Department of Chemical Engineering, Imperial College London, UK |
| 2013 – 2016 | Lecturer, Department of Chemical Engineering, Imperial College London, UK |
| 2009 – 2013 | Group Leader and BHRC Senior Translational Research Fellow (tenure-track), University of Leeds, UK |
| 2007 – 2009 | Postdoctoral Research Associate, Department of Chemical Engineering and Biotechnology, University of Cambridge, UK |
| 2006 – 2007 | Postdoctoral Research Assistant, Department of Chemical Engineering and Biotechnology, University of Cambridge, UK |
| 2003 – 2007 | PhD in Chemical Engineering, University of Cambridge, UK |
| 2000 – 2003 | MSc in Materials Science, Tsinghua University, China |
| 1995 – 1999 | BEng in Chemical Engineering, Beijing Technology and Business University, China |
Selected Publications
Journal Articles
Li Y, Tan T, Zhao Y, et al., 2020, Anticancer polymers via the biginelli reaction, Acs Macro Letters, Vol:9, ISSN:2161-1653, Pages:1249-1254
Chen S, Wu L, Ren J, et al., 2020, Comb-like pseudopeptides enable very rapid and efficient intracellular trehalose delivery for enhanced cryopreservation of erythrocytes, ACS Applied Materials & Interfaces, Vol:12, ISSN:1944-8244, Pages:28941-28951
Tascini AS, Wang S, Seddon JM, et al., 2020, Fats’ love–hate relationships: a molecular dynamics simulation and hands-on experiment outreach activity to introduce the amphiphilic nature and biological functions of lipids to young students and the general public, Journal of Chemical Education, Vol:97, ISSN:0021-9584, Pages:1360-1367
Li L, Xiao B, Mu J, et al., 2019, A MnO2 nanoparticle-dotted hydrogel promotes spinal cord repair via regulating reactive oxygen species microenvironment and synergizing with mesenchymal stem cells, ACS Nano, Vol:13, ISSN:1936-0851, Pages:14283-14293
Kopytynski M, Chen S, Legg S, et al., A versatile polymer‐based platform for intracellular delivery of macromolecules, Advanced Therapeutics, Vol:3, ISSN:2366-3987, Pages:1-10
Huang Y, Yu L, Ren J, et al., 2019, An activated-platelet-sensitive nanocarrier enables targeted delivery of tissue plasminogen activator for effective thrombolytic therapy, Journal of Controlled Release, Vol:300, ISSN:0168-3659, Pages:1-12
He M, Huang L, Hou X, et al., 2019, Efficient ovalbumin delivery using a novel multifunctional micellar platform for targeted melanoma immunotherapy, International Journal of Pharmaceutics, Vol:560, ISSN:0378-5173, Pages:1-10
Tascini AS, Noro MG, Seddon JM, et al., 2019, Mechanisms of lipid extraction from skin lipid bilayers by sebum triglycerides, Physical Chemistry Chemical Physics, Vol:21, ISSN:1463-9076, Pages:1471-1477
Dong R, Liu R, Gaffney P, et al., 2018, Sequence-defined multifunctional polyethers via liquid-phase synthesis with molecular sieving, Nature Chemistry, Vol:11, ISSN:1755-4330, Pages:136-145
Wang S, Ha Y, Huang X, et al., 2018, A new strategy for intestinal drug delivery via pH-responsive and membrane-active nanogels, ACS Applied Materials & Interfaces, Vol:10, ISSN:1944-8244, Pages:36622-36627
Wang S, Chen R, 2017, pH-Responsive, Lysine-Based, Hyperbranched Polymers Mimicking Endosomolytic Cell-Penetrating Peptides for Efficient Intracellular Delivery, Chemistry of Materials, Vol:29, ISSN:0897-4756, Pages:5806-5815
Chen S, Wang S, Kopytynski M, et al., 2017, Membrane-anchoring, comb-like pseudopeptides for efficient, pH-mediated membrane destabilization and intracellular delivery, ACS Applied Materials & Interfaces, Vol:9, ISSN:1944-8244, Pages:8021-8029
Chen S, Chen R, 2016, A Virus-Mimicking, Endosomolytic Liposomal System for Efficient, pH-Triggered Intracellular Drug Delivery, ACS Applied Materials & Interfaces, Vol:8, ISSN:1944-8244, Pages:22457-22467
Bachelet M, Chen R, 2016, Self-assembly of PEGylated gold nanoparticles with satellite structures as seeds, Chemical Communications, Vol:52, ISSN:1364-548X, Pages:9542-9545
Zhang W, Wang F, Wang Y, et al., 2016, pH and near-infrared light dual-stimuli responsive drug delivery using DNA-conjugated gold nanorods for effective treatment of multidrug resistant cancer cells., J Control Release, Vol:232, Pages:9-19
Song L, Guo Y, Roebuck D, et al., 2015, Terminal PEGylated DNA-gold nanoparticle conjugates offering high resistance to nuclease degradation and efficient intracellular delivery of DNA binding agents, ACS Applied Materials & Interfaces, Vol:7, ISSN:1944-8244, Pages:18707-18716
Khormaee S, Choi Y, Shen MJ, et al., 2013, Endosomolytic Anionic Polymer for the Cytoplasmic Delivery of siRNAs in Localized In Vivo Applications, Advanced Functional Materials, Vol:23, ISSN:1616-301X, Pages:565-574
Song L, Ho VHB, Chen C, et al., 2013, Efficient, pH-Triggered Drug Delivery Using a pH-Responsive DNA-Conjugated Gold Nanoparticle, Advanced Healthcare Materials, Vol:2, ISSN:2192-2640, Pages:275-280
Ho VHB, Slater NKH, Chen R, 2011, pH-responsive endosomolytic pseudo-peptides for drug delivery to multicellular spheroids tumour models, Biomaterials, Vol:32, ISSN:0142-9612, Pages:2953-2958