Imperial College London


Faculty of EngineeringDepartment of Chemical Engineering

Reader in Biomaterials Engineering



+44 (0)20 7594 2070rongjun.chen Website




408ACE ExtensionSouth Kensington Campus






Date Role


Reader in Biomaterials Engineering, Department of Chemical Engineering, Imperial College London, UK
2016 2019 Senior Lecturer, Department of Chemical Engineering, Imperial College London, UK
2013 2016 Lecturer, Department of Chemical Engineering, Imperial College London, UK
2009  2013 Group Leader and BHRC Senior Translational Research Fellow (tenure-track), University of Leeds, UK
2007 – 2009 Postdoctoral Research Associate, Department of Chemical Engineering and Biotechnology, University of Cambridge, UK 
2006 – 2007 Postdoctoral Research Assistant, Department of Chemical Engineering and Biotechnology, University of Cambridge, UK
2003 – 2007 PhD in Chemical Engineering, University of Cambridge, UK 
2000 – 2003 MSc in Materials Science, Tsinghua University, China
1995 – 1999 BEng in Chemical Engineering, Beijing Technology and Business University, China

Selected Publications

Journal Articles

Tan P, Cai H, Wei Q, et al., 2021, Enhanced chemo-photodynamic therapy of an enzyme-responsive prodrug in bladder cancer patient-derived xenograft models, Biomaterials, Vol:277, ISSN:0142-9612, Pages:1-13

Huang Y, Gu B, Salles II, et al., 2021, Fibrinogen-mimicking, multi-arm nanovesicles for human thrombus-specific delivery of tissue plasminogen activator and targeted thrombolytic therapy, Science Advances, Vol:7, ISSN:2375-2548

Huang Y, Wang Z, Zhang G, et al., 2021, A pH/redox-dual responsive, nanoemulsion-embedded hydrogel for efficient oral delivery and controlled intestinal release of magnesium ions, Journal of Materials Chemistry B, Vol:9, ISSN:2050-750X, Pages:1888-1895

Li Y, Tan T, Zhao Y, et al., 2020, Anticancer polymers via the biginelli reaction, Acs Macro Letters, Vol:9, ISSN:2161-1653, Pages:1249-1254

Chen S, Wu L, Ren J, et al., 2020, Comb-like pseudopeptides enable very rapid and efficient intracellular trehalose delivery for enhanced cryopreservation of erythrocytes, ACS Applied Materials & Interfaces, Vol:12, ISSN:1944-8244, Pages:28941-28951

Tascini AS, Wang S, Seddon JM, et al., 2020, Fats’ love–hate relationships: a molecular dynamics simulation and hands-on experiment outreach activity to introduce the amphiphilic nature and biological functions of lipids to young students and the general public, Journal of Chemical Education, Vol:97, ISSN:0021-9584, Pages:1360-1367

Li L, Xiao B, Mu J, et al., 2019, A MnO2 nanoparticle-dotted hydrogel promotes spinal cord repair via regulating reactive oxygen species microenvironment and synergizing with mesenchymal stem cells, ACS Nano, Vol:13, ISSN:1936-0851, Pages:14283-14293

Kopytynski M, Chen S, Legg S, et al., 2019, A versatile polymer‐based platform for intracellular delivery of macromolecules, Advanced Therapeutics, Vol:3, ISSN:2366-3987, Pages:1-10

Huang Y, Yu L, Ren J, et al., 2019, An activated-platelet-sensitive nanocarrier enables targeted delivery of tissue plasminogen activator for effective thrombolytic therapy, Journal of Controlled Release, Vol:300, ISSN:0168-3659, Pages:1-12

He M, Huang L, Hou X, et al., 2019, Efficient ovalbumin delivery using a novel multifunctional micellar platform for targeted melanoma immunotherapy, International Journal of Pharmaceutics, Vol:560, ISSN:0378-5173, Pages:1-10

Dong R, Liu R, Gaffney P, et al., 2019, Sequence-defined multifunctional polyethers via liquid-phase synthesis with molecular sieving, Nature Chemistry, Vol:11, ISSN:1755-4330, Pages:136-145

Tascini AS, Noro MG, Seddon JM, et al., 2019, Mechanisms of lipid extraction from skin lipid bilayers by sebum triglycerides, Physical Chemistry Chemical Physics, Vol:21, ISSN:1463-9076, Pages:1471-1477

Wang S, Ha Y, Huang X, et al., 2018, A new strategy for intestinal drug delivery via pH-responsive and membrane-active nanogels, ACS Applied Materials & Interfaces, Vol:10, ISSN:1944-8244, Pages:36622-36627

Wang S, Chen R, 2017, pH-Responsive, Lysine-Based, Hyperbranched Polymers Mimicking Endosomolytic Cell-Penetrating Peptides for Efficient Intracellular Delivery, Chemistry of Materials, Vol:29, ISSN:0897-4756, Pages:5806-5815

Chen S, Wang S, Kopytynski M, et al., 2017, Membrane-anchoring, comb-like pseudopeptides for efficient, pH-mediated membrane destabilization and intracellular delivery, ACS Applied Materials & Interfaces, Vol:9, ISSN:1944-8244, Pages:8021-8029

Chen S, Chen R, 2016, A virus-mimicking, endosomolytic liposomal system for efficient, pH-triggered intracellular drug delivery, ACS Applied Materials & Interfaces, Vol:8, ISSN:1944-8244, Pages:22457-22467

Bachelet M, Chen R, 2016, Self-assembly of PEGylated gold nanoparticles with satellite structures as seeds, Chemical Communications, Vol:52, ISSN:1364-548X, Pages:9542-9545

Zhang W, Wang F, Wang Y, et al., 2016, pH and near-infrared light dual-stimuli responsive drug delivery using DNA-conjugated gold nanorods for effective treatment of multidrug resistant cancer cells., J Control Release, Vol:232, Pages:9-19

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