Summary
Biography
| Date | Role |
|---|---|
| 2016- | Senior Lecturer, Department of Chemical Engineering, Imperial College London, UK |
| 2013-2016 | Lecturer, Department of Chemical Engineering, Imperial College London, UK |
| 2009-2013 |
Group Leader and BHRC Senior Translational Research Fellow (tenure-track), Biomedical and Health Research Centre, Centre for Molecular Nanoscience and School of Chemistry, University of Leeds, UK |
| 2007-2009 | Postdoctoral Research Associate, Department of Chemical Engineering and Biotechnology, University of Cambridge, UK |
| 2006-2007 | Postdoctoral Research Assistant, Department of Chemical Engineering and Biotechnology, University of Cambridge, UK |
| 2003-2007 | PhD in Chemical Engineering, University of Cambridge, UK |
| 2000-2003 | MSc in Materials Science, Tsinghua University, China |
| 1995-1999 | BEng in Chemical Engineering, Beijing Technology and Business University, China |
Selected Publications
Journal Articles
Huang Y, Yu L, Ren J, et al., 2019, An activated-platelet-sensitive nanocarrier enables targeted delivery of tissue plasminogen activator for effective thrombolytic therapy, Journal of Controlled Release, Vol:300, ISSN:0168-3659, Pages:1-12
He M, Huang L, Hou X, et al., 2019, Efficient ovalbumin delivery using a novel multifunctional micellar platform for targeted melanoma immunotherapy, International Journal of Pharmaceutics, Vol:560, ISSN:0378-5173, Pages:1-10
Tascini AS, Noro MG, Seddon JM, et al., 2019, Mechanisms of lipid extraction from skin lipid bilayers by sebum triglycerides, Physical Chemistry Chemical Physics, Vol:21, ISSN:1463-9076, Pages:1471-1477
Dong R, Liu R, Gaffney P, et al., 2018, Sequence-defined multifunctional polyethers via liquid-phase synthesis with molecular sieving, Nature Chemistry, Vol:11, ISSN:1755-4330, Pages:136-145
Wang S, Ha Y, Huang X, et al., 2018, A new strategy for intestinal drug delivery via pH-responsive and membrane-active nanogels, ACS Applied Materials & Interfaces, Vol:10, ISSN:1944-8244, Pages:36622-36627
Wang S, Chen R, 2017, pH-Responsive, Lysine-Based, Hyperbranched Polymers Mimicking Endosomolytic Cell-Penetrating Peptides for Efficient Intracellular Delivery, Chemistry of Materials, Vol:29, ISSN:0897-4756, Pages:5806-5815
Chen S, Wang S, Kopytynski M, et al., 2017, Membrane-anchoring, comb-like pseudopeptides for efficient, pH-mediated membrane destabilization and intracellular delivery, ACS Applied Materials & Interfaces, Vol:9, ISSN:1944-8244, Pages:8021-8029
Chen S, Chen R, 2016, A Virus-Mimicking, Endosomolytic Liposomal System for Efficient, pH-Triggered Intracellular Drug Delivery, ACS Applied Materials & Interfaces, Vol:8, ISSN:1944-8244, Pages:22457-22467
Bachelet M, Chen R, 2016, Self-assembly of PEGylated gold nanoparticles with satellite structures as seeds, Chemical Communications, Vol:52, ISSN:1364-548X, Pages:9542-9545
Zhang W, Wang F, Wang Y, et al., 2016, pH and near-infrared light dual-stimuli responsive drug delivery using DNA-conjugated gold nanorods for effective treatment of multidrug resistant cancer cells., J Control Release, Vol:232, Pages:9-19
Khormaee S, Choi Y, Shen MJ, et al., 2013, Endosomolytic Anionic Polymer for the Cytoplasmic Delivery of siRNAs in Localized In Vivo Applications, Advanced Functional Materials, Vol:23, ISSN:1616-301X, Pages:565-574
Ho VHB, Slater NKH, Chen R, 2011, pH-responsive endosomolytic pseudo-peptides for drug delivery to multicellular spheroids tumour models, Biomaterials, Vol:32, ISSN:0142-9612, Pages:2953-2958
Liechty WB, Chen R, Farzaneh F, et al., 2009, Synthetic pH-Responsive Polymers for Protein Transduction, Advanced Materials, Vol:21, ISSN:0935-9648, Pages:3910-+
Patents
Gaffney P, Livingston A, Chen R, et al., 2017, Defined Monomer Sequence Polymers, WO/2017/042583
Chen R, Chen S, Wu L, 2016, Modified Peptide, GB1612150.1
Slater NKH, Lynch A, Chen R, 2011, Mammalian cell preservation methods, WO/2011/089391