Imperial College London

ProfessorRongjunChen

Faculty of EngineeringDepartment of Chemical Engineering

Professor of Biomaterials Engineering
 
 
 
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Contact

 

+44 (0)20 7594 2070rongjun.chen Website

 
 
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Location

 

408ACE ExtensionSouth Kensington Campus

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Summary

 

Publications

Citation

BibTex format

@inbook{Chen:2019:10.1016/B978-0-444-64046-8.00451-1,
author = {Chen, S and Ren, J and Chen, R},
booktitle = {Comprehensive Biotechnology},
doi = {10.1016/B978-0-444-64046-8.00451-1},
editor = {Moo-Young},
pages = {157--166},
publisher = {Pergamon},
title = {Cryopreservation and Desiccation Preservation of Cells},
url = {http://dx.doi.org/10.1016/B978-0-444-64046-8.00451-1},
year = {2019}
}

RIS format (EndNote, RefMan)

TY  - CHAP
AB - Cell preservation technology is required to retain cell viability and functionality during storage. It is of critical importance for the development of biobanks and the delivery of emerging cell-based therapies including blood transfusion, immunotherapy, reparative and regenerative medicine, and fertility preservation. Cryopreservation at ultralow temperature is currently the main way of long-term cell storage. Preservation of cells in dried state at room temperature is an attractive strategy to overcome the limitations of refrigeration and enable easy transportation. Although achievements have been made in preservation of human, animal and bacteria cells, there is still much space for improving their survival rate and functionality. Cell injuries may easily occur during freezing and drying steps, especially for mammalian cells which are more delicate and freezing/desiccation sensitive. This article reviews the mechanisms of cell damage, describes the challenges for cell preservation, and presents the technologies and protectants used in this rapidly growing field.
AU - Chen,S
AU - Ren,J
AU - Chen,R
DO - 10.1016/B978-0-444-64046-8.00451-1
EP - 166
PB - Pergamon
PY - 2019///
SN - 9780444640468
SP - 157
TI - Cryopreservation and Desiccation Preservation of Cells
T1 - Comprehensive Biotechnology
UR - http://dx.doi.org/10.1016/B978-0-444-64046-8.00451-1
ER -