Imperial College London

Professor Sir Roy Anderson FRS, FMedSci

Faculty of MedicineSchool of Public Health

Professor in Infectious Disease Epidemiology
 
 
 
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Contact

 

+44 (0)20 7594 3399roy.anderson

 
 
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Assistant

 

Mrs Clare Mylchreest +44 (0)20 7594 9162

 
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Location

 

LG35Norfolk PlaceSt Mary's Campus

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Summary

 

Publications

Publication Type
Year
to

451 results found

Anderson RM, 2015, Preface, Publisher: ROYAL SOC

BOOK CHAPTER

Anderson RM, Turner HC, Farrell SH, Yang J, Truscott JEet al., 2015, What is required in terms of mass drug administration to interrupt the transmission of schistosome parasites in regions of endemic infection?, PARASITES & VECTORS, Vol: 8, ISSN: 1756-3305

JOURNAL ARTICLE

Anderson RM, Turner HC, Truscott JE, Hollingsworth TD, Brooker SJet al., 2015, Should the Goal for the Treatment of Soil Transmitted Helminth (STH) Infections Be Changed from Morbidity Control in Children to Community-Wide Transmission Elimination?, PLOS NEGLECTED TROPICAL DISEASES, Vol: 9, ISSN: 1935-2735

JOURNAL ARTICLE

Basanez M-G, Anderson RM, 2015, ADVANCES IN PARASITOLOGY Mathematical Models for Neglected Tropical Diseases: Essential Tools for Control and Elimination, Part A PREFACE, Publisher: ELSEVIER ACADEMIC PRESS INC, ISBN: 978-0-12-803256-5

BOOK

Basáñez M-G, Anderson RM, 2015, Mathematical Models for Neglected Tropical Diseases: Essential Tools for Control and Elimination, Part A., Adv Parasitol, Vol: 87, Pages: xiii-xvii

JOURNAL ARTICLE

Brooker SJ, Mwandawiro CS, Halliday KE, Njenga SM, Mcharo C, Gichuki PM, Wasunna B, Kihara JH, Njomo D, Alusala D, Chiguzo A, Turner HC, Teti C, Gwayi-Chore C, Nikolay B, Truscott JE, Hollingsworth TD, Balabanova D, Griffiths UK, Freeman MC, Allen E, Pullan RL, Anderson RMet al., 2015, Interrupting transmission of soil-transmitted helminths: a study protocol for cluster randomised trials evaluating alternative treatment strategies and delivery systems in Kenya, BMJ OPEN, Vol: 5, ISSN: 2044-6055

JOURNAL ARTICLE

Cui H, Lu Y, Khan MZ, Anderson RM, McDaniel L, Wilson HE, Yin TC, Radley JJ, Pieper AA, Lutter Met al., 2015, Behavioral disturbances in estrogen-related receptor alpha-null mice., Cell Rep, Vol: 11, Pages: 344-350

Eating disorders, such as anorexia nervosa and bulimia nervosa, are common and severe mental illnesses of unknown etiology. Recently, we identified a rare missense mutation in the transcription factor estrogen-related receptor alpha (ESRRA) that is associated with the development of eating disorders. However, little is known about ESRRA function in the brain. Here, we report that Esrra is expressed in the mouse brain and demonstrate that Esrra levels are regulated by energy reserves. Esrra-null female mice display a reduced operant response to a high-fat diet, compulsivity/behavioral rigidity, and social deficits. Selective Esrra knockdown in the prefrontal and orbitofrontal cortices of adult female mice recapitulates reduced operant response and increased compulsivity, respectively. These results indicate that Esrra deficiency in the mouse brain impairs behavioral responses in multiple functional domains.

JOURNAL ARTICLE

Heesterbeek H, Anderson RM, Andreasen V, Bansal S, De Angelis D, Dye C, Eames KTD, Edmunds WJ, Frost SDW, Funk S, Hollingsworth TD, House T, Isham V, Klepac P, Lessler J, Lloyd-Smith JO, Metcalf CJE, Mollison D, Pellis L, Pulliam JRC, Roberts MG, Viboud Cet al., 2015, Modeling infectious disease dynamics in the complex landscape of global health, SCIENCE, Vol: 347, Pages: 1216-U29, ISSN: 0036-8075

JOURNAL ARTICLE

Hollingsworth TD, Adams ER, Anderson RM, Atkins K, Bartsch S, Basanez M-G, Behrend M, Blok DJ, Chapman LAC, Coffeng L, Courtenay O, Crump RE, de Vlas SJ, Dobson A, Dyson L, Farkas H, Galvani AP, Gambhir M, Gurarie D, Irvine MA, Jervis S, Keeling MJ, Kelly-Hope L, King C, Lee BY, Le Rutte EA, Lietman TM, Ndeffo-Mbah M, Medley GF, Michael E, Pandey A, Peterson JK, Pinsent A, Porco TC, Richardus JH, Reimer L, Rock KS, Singh BK, Stolk W, Swaminathan S, Torr SJ, Townsend J, Truscott J, Walker M, Zoueva Aet al., 2015, Quantitative analyses and modelling to support achievement of the 2020 goals for nine neglected tropical diseases, PARASITES & VECTORS, Vol: 8, ISSN: 1756-3305

JOURNAL ARTICLE

Levecke B, Anderson RM, Berkvens D, Charlier J, Devleesschauwer B, Speybroeck N, Vercruysse J, Van Aelst Set al., 2015, Mathematical Inference on Helminth Egg Counts in Stool and Its Applications in Mass Drug Administration Programmes to Control Soil-Transmitted Helminthiasis in Public Health, MATHEMATICAL MODELS FOR NEGLECTED TROPICAL DISEASES: ESSENTIAL TOOLS FOR CONTROL AND ELIMINATION, PT A, Vol: 87, Pages: 193-247, ISSN: 0065-308X

JOURNAL ARTICLE

Nikolay B, Mwandawiro CS, Kihara JH, Okoyo C, Cano J, Mwanje MT, Sultani H, Alusala D, Turner HC, Teti C, Garn J, Freeman MC, Allen E, Anderson RM, Pullan RL, Njenga SM, Brooker SJet al., 2015, Understanding Heterogeneity in the Impact of National Neglected Tropical Disease Control Programmes: Evidence from School-Based Deworming in Kenya, PLOS NEGLECTED TROPICAL DISEASES, Vol: 9, ISSN: 1935-2735

JOURNAL ARTICLE

Spratt BG, Anderson RM, 2015, Special feature on evolution and genetics in medicine, Proceedings of the Royal Society B: Biological Sciences, Vol: 282, ISSN: 0962-8452

JOURNAL ARTICLE

Turner HC, Truscott JE, Bettis AA, Shuford KV, Dunn JC, Hollingsworth TD, Brooker SJ, Anderson RMet al., 2015, An economic evaluation of expanding hookworm control strategies to target the whole community, PARASITES & VECTORS, Vol: 8, ISSN: 1756-3305

JOURNAL ARTICLE

Turner HC, Truscott JE, Hollingsworth TD, Bettis AA, Brooker SJ, Anderson RMet al., 2015, Cost and cost-effectiveness of soil-transmitted helminth treatment programmes: systematic review and research needs, PARASITES & VECTORS, Vol: 8, ISSN: 1756-3305

JOURNAL ARTICLE

Anderson R, Truscott J, Hollingsworth TD, 2014, The coverage and frequency of mass drug administration required to eliminate persistent transmission of soil-transmitted helminths, PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES, Vol: 369, ISSN: 0962-8436

JOURNAL ARTICLE

Truscott J, Hollingsworth TD, Anderson R, 2014, Modeling the Interruption of the Transmission of Soil-Transmitted Helminths by Repeated Mass Chemotherapy of School-Age Children, PLOS NEGLECTED TROPICAL DISEASES, Vol: 8, ISSN: 1935-2735

JOURNAL ARTICLE

Truscott JE, Hollingsworth TD, Brooker SJ, Anderson RMet al., 2014, Can chemotherapy alone eliminate the transmission of soil transmitted helminths?, PARASITES & VECTORS, Vol: 7, ISSN: 1756-3305

JOURNAL ARTICLE

Anderson RM, 2013, Polemics or philosophy? Musical pathology in Eduard Hanslick's Vom Musikalisch-Schonen, MUSICAL TIMES, Vol: 154, Pages: 65-76, ISSN: 0027-4666

JOURNAL ARTICLE

Anderson RM, Truscott JE, Pullan RL, Brooker SJ, Hollingsworth TDet al., 2013, How Effective Is School-Based Deworming for the Community-Wide Control of Soil-Transmitted Helminths?, PLOS NEGLECTED TROPICAL DISEASES, Vol: 7, ISSN: 1935-2735

JOURNAL ARTICLE

Hollingsworth TD, Truscott JE, Anderson RM, 2013, Transmission Dynamics of Ascaris lumbricoides - Theory and Observation, Ascaris: The Neglected Parasite, Pages: 231-262, ISBN: 9780123969781

Mathematical models are playing an increasing role in the design and optimization of control programs for many infectious diseases. In the case of Ascaris lumbricoides, there is a long history of models to understand the biology and epidemiology and to design control programs. We outline the key insights which models have given on the dynamics of Ascaris transmission, describe the model structures and discuss how current and future models are informing the design of control programs in the era of both increased access to donate drugs and new statistical techniques to validate these models against reinfection data. We show how the "bounce-back" time following a treatment round, when infection levels monotonically increase to baseline levels, are driven by the life expectancy of the parasite and the basic reproductive number. We also show that the effect of treatment in subsets of the population, for example school children, depends on the extent to which different subpopulations interact with the egg output of the treated group. We discuss the outstanding policy questions which models can be used to answer and the data and model development required to address them. © 2013 Copyright © 2013 Elsevier Inc. All rights reserved.

BOOK CHAPTER

Anderson R, Hollingsworth TD, Truscott J, Brooker Set al., 2012, Optimisation of mass chemotherapy to control soil-transmitted helminth infection, LANCET, Vol: 379, Pages: 289-290, ISSN: 0140-6736

JOURNAL ARTICLE

Anderson RM, Hollingsworth TD, Truscott J, Brooker Set al., 2012, Optimisation of mass chemotherapy to control soil-transmitted helminth infection., Lancet, Pages: 289-290

JOURNAL ARTICLE

Anderson RM, Hollingsworth TD, Truscott J, Brooker Set al., 2012, Erratum: Optimisation of mass chemotherapy to control soil-transmitted helminth infection (Lancet (2012) 379 (289-90)), The Lancet, Vol: 379, ISSN: 0140-6736

JOURNAL ARTICLE

Anderson RM, Hollingsworth TD, Truscott J, Brooker Set al., 2012, Optimisation of mass chemotherapy to control soil-transmitted helminth infection (vol 379, pg 289, 2012), LANCET, Vol: 379, Pages: 1102-1102, ISSN: 0140-6736

JOURNAL ARTICLE

Hollingsworth TD, Klinkenberg D, Heesterbeek H, Anderson RMet al., 2011, Mitigation Strategies for Pandemic Influenza A: Balancing Conflicting Policy Objectives, PLOS COMPUTATIONAL BIOLOGY, Vol: 7, ISSN: 1553-7358

JOURNAL ARTICLE

Kounaves SP, Stroble ST, Anderson RM, Moore Q, Catling DC, Douglas S, McKay CP, Ming DW, Smith PH, Tamppari LK, Zent APet al., 2010, Discovery of Natural Perchlorate in the Antarctic Dry Valleys and Its Global Implications, ENVIRONMENTAL SCIENCE & TECHNOLOGY, Vol: 44, Pages: 2360-2364, ISSN: 0013-936X

JOURNAL ARTICLE

Anderson RM, 2009, How well are we managing the influenza A/H1N1 pandemic in the UK?, BRITISH MEDICAL JOURNAL, Vol: 339, ISSN: 0959-8146

JOURNAL ARTICLE

Anderson RM, Hollingsworth TD, Nokes DJ, 2009, Mathematical models of transmission and control, Oxford Textbook of Public Health, Editors: Detels, Beaglehole, Lansang, Gulliford, Oxford, UK, Publisher: Oxford University Press, ISBN: 9780199218707

BOOK CHAPTER

Walker M, Hall A, Anderson RM, Basanez M-Get al., 2009, Density-dependent effects on the weight of female Ascaris lumbricoides infections of humans and its impact on patterns of egg production, PARASITES & VECTORS, Vol: 2, ISSN: 1756-3305

JOURNAL ARTICLE

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