Imperial College London

Professor Sir Roy Anderson FRS, FMedSci

Faculty of MedicineSchool of Public Health

Professor in Infectious Disease Epidemiology
 
 
 
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Contact

 

+44 (0)20 7594 3399roy.anderson

 
 
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Assistant

 

Mrs Clare Mylchreest +44 (0)20 7594 9162

 
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Location

 

LG35Norfolk PlaceSt Mary's Campus

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Summary

 

Publications

Publication Type
Year
to

451 results found

Bocharov G, Ludewig B, Bertoletti A, Klenerman P, Junt T, Krebs P, Luzyanina T, Fraser C, Anderson RMet al., 2004, Underwhelming the immune response: Effect of slow virus growth on CD8(+)-T-lymphocyte responses, JOURNAL OF VIROLOGY, Vol: 78, Pages: 2247-2254, ISSN: 0022-538X

JOURNAL ARTICLE

Brooker S, Whawell S, Kabatereine NB, Fenwick A, Anderson RMet al., 2004, Evaluating the epidemiological impact of national control programmes for helminths, TRENDS IN PARASITOLOGY, Vol: 20, Pages: 537-545, ISSN: 1471-4922

JOURNAL ARTICLE

Donnelly CA, Fisher MC, Fraser C, Ghani AC, Riley S, Ferguson NM, Anderson RMet al., 2004, Epidemiological and genetic analysis of severe acute respiratory syndrome, LANCET INFECTIOUS DISEASES, Vol: 4, Pages: 672-683, ISSN: 1473-3099

JOURNAL ARTICLE

Ferguson NM, Fraser C, Donnelly CA, Ghani AC, Anderson RMet al., 2004, Public health risk from the avian H5N1 influenza epidemic, SCIENCE, Vol: 304, Pages: 968-969, ISSN: 0036-8075

JOURNAL ARTICLE

Fraser C, Riley S, Anderson RM, Ferguson NMet al., 2004, Factors that make an infectious disease outbreak controllable, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Vol: 101, Pages: 6146-6151, ISSN: 0027-8424

JOURNAL ARTICLE

G M Leung, A J Hedley, L M Ho, P Chau, I O Wong, T Q Thach, A C Ghani, C A Donnelly, C Fraser, S Riley, N M Ferguson, R M Anderson, T Tsang, P Y Leung, V Wong, J C Chan, E Tsui, S V Lo, T H Lamet al., 2004, The epidemiology of severe acute respiratory syndrome in the 2003 Hong Kong epidemic: an analysis of all 1755 patients, Ann Intern Med, Vol: 141, Pages: 662-673, ISSN: 0003-4819

JOURNAL ARTICLE

Leung GM, Chung PH, Tsang T, Lim W, Chan SKK, Chau P, Donnelly CA, Ghani AC, Fraser C, Riley S, Ferguson NM, Anderson RM, Law YI, Mok T, Ng T, Fu A, Leung PY, Peiris JSM, Lam TH, Hedley AJet al., 2004, SARS-CoV antibody prevalence in all Hong Kong patient contacts, EMERGING INFECTIOUS DISEASES, Vol: 10, Pages: 1653-1656, ISSN: 1080-6040

JOURNAL ARTICLE

Ludewig B, Krebs P, Junt T, Metters H, Ford NJ, Anderson RM, Bocharov Get al., 2004, Determining control parameters for dendritic cell-cytotoxic T lymphocyte interaction, EUROPEAN JOURNAL OF IMMUNOLOGY, Vol: 34, Pages: 2407-2418, ISSN: 0014-2980

JOURNAL ARTICLE

Schneeberger A, Mercer CH, Gregson SAJ, Ferguson NM, Nyamukapa CA, Anderson RM, Johnson AM, Garnett GPet al., 2004, Scale-free networks and sexually transmitted diseases - A description of observed patterns of sexual contacts in Britain and Zimbabwe, SEXUALLY TRANSMITTED DISEASES, Vol: 31, Pages: 380-387, ISSN: 0148-5717

JOURNAL ARTICLE

Anderson RM, Grassly N, Garnett GP, 2003, Success in HIV control: Fact or Fiction., Bulletin of the World Health Organization, Vol: 10, Pages: 23-30

JOURNAL ARTICLE

Desai K, Boily MC, Masse BR, Anderson RMet al., 2003, Detecting vaccine efficacy in phase III HIV clinical trials: a HARE raising question., Controlled Clinical Trials, Vol: 28, Pages: 56-67

JOURNAL ARTICLE

Donnelly CA, Ferguson NM, Ghani AC, Anderson RMet al., 2003, Extending backcalculation to analyse BSE data, STATISTICAL METHODS IN MEDICAL RESEARCH, Vol: 12, Pages: 177-190, ISSN: 0962-2802

JOURNAL ARTICLE

Donnelly CA, Ghani AC, Leung GM, Hedley AJ, Fraser C, Riley S, Abu-Raddad LJ, Ho LM, Thach TQ, Chau P, Chan KP, Lam TH, Tse LY, Tsang T, Liu SH, Kong JHB, Lau EMC, Ferguson NM, Anderson RMet al., 2003, Epidemiological determinants of spread of causal agent of severe acute respiratory syndrome in Hong Kong, LANCET, Vol: 361, Pages: 1761-1766, ISSN: 0140-6736

JOURNAL ARTICLE

Ferguson NM, Keeling MJ, Edmunds WJ, Gant R, Grenfell BT, Amderson RM, Leach Set al., 2003, Planning for smallpox outbreaks, NATURE, Vol: 425, Pages: 681-685, ISSN: 0028-0836

JOURNAL ARTICLE

Fraser C, Anderson RM, 2003, HIV viral sex: inbreeding, recombination, drug resistance and clinical outcome, 12th International HIV Drug Resistance Workshop, Publisher: INT MEDICAL PRESS LTD, Pages: U68-U69, ISSN: 1359-6535

CONFERENCE PAPER

Fraser C, Anderson RM, 2003, HIV viral sex: inbreeding, recombination, drug resistance and clinical outcome., Antiviral Therapy, Vol: 8, Pages: U68-U69

JOURNAL ARTICLE

Ghani AC, Donnelly CA, Anderson RM, 2003, Patterns of antiretroviral use in the United States of America: analysis of three observational databases., HIV Med, Vol: 4, Pages: 24-32, ISSN: 1464-2662

OBJECTIVE: To characterize patterns of antiretroviral use in HIV-infected patients and explore variation by patient characteristics and disease stage. METHODS: Three large patient databases recording information derived from routine clinical attendance were analyzed: HIV Insight (n = 10 873), Target Management Services (n = 2226) and Clinical Partners (n = 1505). Each database records the dates of starting and stopping individual antiretroviral agents over time, measurements of CD4 T-cell counts and HIV-RNA levels at approximately 6-monthly intervals, and the demographic characteristics of patients. The number, frequency and duration of different antiretroviral combinations over time and their relationship to stage of HIV-disease and demographic characteristics were explored. RESULTS: Over 2000 different combinations of antiretroviral agents are recorded. From 1987 onwards, the use of zidovudine increased, with 23% of patients receiving monotherapy by 1990. The majority of treated patients remained on monotherapy until the introduction of highly active antiretroviral therapy (HAART) in 1996. By 1999, the standard of care was HAART, with 84% of patients beginning antiretroviral therapy with HAART. Those of African American race (odds ratio 0.59) and funded by Medicaid (odds ratio 0.72) were significantly less likely to begin antiretroviral therapy on HAART. Until 1995, there was a significant decrease in CD4 T-cell count when starting antiretroviral therapy. No significant trend was observed in either CD4 T-cell count or viral load after this time. Those starting on HAART therapies were significantly less likely to stop or switch regimens than those on nucleoside reverse transcriptase inhibitor (NRTI)-only therapies (P < 0.001). CONCLUSIONS: Complex patterns of antiretroviral treatment are observed in this large population. Changes over time mirror the introduction of the new antiretroviral agents.

JOURNAL ARTICLE

Ghani AC, Donnelly CA, Ferguson NM, Anderson RMet al., 2003, Updated projections of future vCJD deaths in the UK, BMC INFECTIOUS DISEASES, Vol: 3, ISSN: 1471-2334

JOURNAL ARTICLE

Ghani AC, Ferguson NM, Donnelly CA, Anderson RMet al., 2003, Short-term projections for variant Creutzfeldt-Jakob disease onsets, STATISTICAL METHODS IN MEDICAL RESEARCH, Vol: 12, Pages: 191-201, ISSN: 0962-2802

JOURNAL ARTICLE

Ghani AC, Ferguson NM, Donnelly CA, Anderson RMet al., 2003, Factors determining the pattern of the variant Creutzfeldt-Jakob disease (vCJD) epidemic in the UK, PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES, Vol: 270, Pages: 689-698, ISSN: 0962-8452

JOURNAL ARTICLE

Hagenaars TJ, Donnelly CA, Ferguson NM, Anderson RMet al., 2003, Dynamics of a scrapie outbreak in a flock of Romanov sheep - estimation of transmission parameters, EPIDEMIOLOGY AND INFECTION, Vol: 131, Pages: 1015-1022, ISSN: 0950-2688

JOURNAL ARTICLE

Riley S, Fraser C, Donnelly CA, Ghani AC, Abu-Raddad LJ, Hedley AJ, Leung GM, Ho LM, Lam TH, Thach TQ, Chau P, Chan KP, Leung PY, Tsang T, Ho W, Lee KH, Lau EMC, Ferguson NM, Anderson RMet al., 2003, Transmission dynamics of the etiological agent of SARS in Hong Kong: Impact of public health interventions, SCIENCE, Vol: 300, Pages: 1961-1966, ISSN: 0036-8075

JOURNAL ARTICLE

Anderson RM, 2002, Herd immunity and the design of vaccination programs, Workshop on the Consequences of Viral Disease Eradication, Publisher: NATL ACADEMIES PRESS, Pages: 65-77

CONFERENCE PAPER

Atkinson RPD, Rhodes CJ, Macdonald DW, Anderson RMet al., 2002, Scale-free dynamics in the movement patterns of jackals, OIKOS, Vol: 98, Pages: 134-140, ISSN: 0030-1299

JOURNAL ARTICLE

Bartley LM, Donnelly CA, Anderson RM, 2002, Review of foot-and-mouth disease virus survival in animal excretions and on fomites, VETERINARY RECORD, Vol: 151, Pages: 667-669, ISSN: 0042-4900

JOURNAL ARTICLE

Donnelly CA, Ferguson NM, Ghani AC, Anderson RMet al., 2002, Implications of BSE infection screening data for the scale of the British BSE epidemic and current European infection levels, PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES, Vol: 269, Pages: 2179-2190, ISSN: 0962-8452

JOURNAL ARTICLE

Ferguson NM, Anderson RM, 2002, Predicting evolutionary change in the influenza A virus, NATURE MEDICINE, Vol: 8, Pages: 562-563, ISSN: 1078-8956

JOURNAL ARTICLE

Ferguson NM, Ghani AC, Donnelly CA, Hagenaars TJ, Anderson RMet al., 2002, Estimating the human health risk from possible BSE infection of the British sheep flock, NATURE, Vol: 415, Pages: 420-424, ISSN: 0028-0836

JOURNAL ARTICLE

Fraser C, Ferguson NM, de Wolf F, Ghani AC, Garnett GR, Anderson RMet al., 2002, Antigen-driven T-cell turnover, JOURNAL OF THEORETICAL BIOLOGY, Vol: 219, Pages: 177-192, ISSN: 0022-5193

JOURNAL ARTICLE

Garnett GP, Bartley L, Grassly NC, Anderson RMet al., 2002, Antiretroviral therapy to treat and prevent HIV/AIDS in resource-poor settings, NATURE MEDICINE, Vol: 8, Pages: 651-654, ISSN: 1078-8956

JOURNAL ARTICLE

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