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@article{Coffeng:2019:infdis/jiz535,
author = {Coffeng, L and Malizia, V and Vegvari, C and Cools, P and Halliday, KE and Levecke, B and Mekonnen, Z and Gichuki, PM and Sayasone, S and Sarkar, R and Shaali, A and Vlaminck, J and Anderson, RM and de, Vlas SJ},
doi = {infdis/jiz535},
journal = {Journal of Infectious Diseases},
pages = {S531--S538},
title = {Impact of different sampling schemes for decision making in soil-transmitted helminthiasis control programs},
url = {http://dx.doi.org/10.1093/infdis/jiz535},
volume = {221},
year = {2019}
}

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TY  - JOUR
AB  - Starting and stopping preventive chemotherapy (PC) for soil-transmitted helminthiasis is typically based on the prevalence of infection as measured by Kato-Katz (KK) fecal smears. Kato-Katz-based egg counts can vary highly over repeated stool samples and smears. Consequentially, the sensitivity of KK-based surveys depends on the number of stool samples per person and the number of smears per sample. Given finite resources, collecting multiple samples and/or smears means screening fewer individuals, thereby lowering the statistical precision of prevalence estimates. Using population-level data from various epidemiological settings, we assessed the performance of different sampling schemes executed within the confines of the same budget. We recommend the use of single-slide KK for determining prevalence of moderate-to-heavy intensity infection and policy decisions for starting and continuing PC; more sensitive sampling schemes may be required for policy decisions involving stopping PC. Our findings highlight that guidelines should include specific guidance on sampling schemes.
AU  - Coffeng,L
AU  - Malizia,V
AU  - Vegvari,C
AU  - Cools,P
AU  - Halliday,KE
AU  - Levecke,B
AU  - Mekonnen,Z
AU  - Gichuki,PM
AU  - Sayasone,S
AU  - Sarkar,R
AU  - Shaali,A
AU  - Vlaminck,J
AU  - Anderson,RM
AU  - de,Vlas SJ
DO  - infdis/jiz535
EP  - 538
PY  - 2019///
SN  - 0022-1899
SP  - 531
TI  - Impact of different sampling schemes for decision making in soil-transmitted helminthiasis control programs
T2  - Journal of Infectious Diseases
UR  - http://dx.doi.org/10.1093/infdis/jiz535
UR  - http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000544191700006&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
UR  - https://academic.oup.com/jid/article/221/Supplement_5/S531/5673766
UR  - http://hdl.handle.net/10044/1/82105
VL  - 221
ER  -

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Professor Sir Roy Anderson FRS, FMedSci

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