Imperial College London
Alternate

ProfessorRylieGreen

Faculty of Engineering, Department of Bioengineering

Head of the Department of Bioengineering
 
 
 
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Contact

 

+44 (0)20 7594 0943rylie.green

 
 
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Location

 

3.05Bessemer BuildingSouth Kensington Campus

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Summary

 

Publications

Citation

BibTex format

@article{Goding:2019:10.1039/c8tb02763c,
author = {Goding, J and Vallejo-Giraldo, C and Syed, O and Green, R},
doi = {10.1039/c8tb02763c},
journal = {Journal of Materials Chemistry B},
pages = {1625--1636},
title = {Considerations for hydrogel applications to neural bioelectronics},
url = {http://dx.doi.org/10.1039/c8tb02763c},
volume = {7},
year = {2019}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - © 2019 The Royal Society of Chemistry. Hydrogels have been applied across a wide range of biomedical applications due to their versatility, but more recently have garnered interest as materials in bioelectronics due to the capacity to tailor their mechanical and biological properties. Hydrogel coatings in particular have been used to impart softness at the bionic device interface, deliver therapeutics and control cell interactions through presentation of peptides and growth factors. Additionally, the use of dynamic hydrogel properties has been harnessed as shuttles for the implantation of flexible electrode arrays. In all of these applications, the hydrogel must be designed not only to provide the desired performance, but also have no unexpected impacts on the surrounding tissues, such as extensive swelling that can compress the cells at the interface. Appropriate selection and design of hydrogel systems for bioelectronics requires an understanding of the physical, chemical and biological properties of hydrogels as well as their structure-property relationships. This review covers the design rationale for application of hydrogels systems for use in bioelectronic devices with a focus on in vivo applications.
AU  - Goding,J
AU  - Vallejo-Giraldo,C
AU  - Syed,O
AU  - Green,R
DO  - 10.1039/c8tb02763c
EP  - 1636
PY  - 2019///
SN  - 2050-7518
SP  - 1625
TI  - Considerations for hydrogel applications to neural bioelectronics
T2  - Journal of Materials Chemistry B
UR  - http://dx.doi.org/10.1039/c8tb02763c
VL  - 7
ER  -
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