Imperial College London
Alternate

ProfessorRylieGreen

Faculty of Engineering, Department of Bioengineering

Head of the Department of Bioengineering
 
 
 
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Contact

 

+44 (0)20 7594 0943rylie.green

 
 
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Location

 

3.05Bessemer BuildingSouth Kensington Campus

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Summary

 

Publications

Citation

BibTex format

@article{Cuttaz:2021:10.1002/advs.202004033,
author = {Cuttaz, EA and Chapman, CAR and Syed, O and Goding, JA and Green, RA},
doi = {10.1002/advs.202004033},
journal = {Advanced Science},
pages = {1--14},
title = {Stretchable, fully polymeric electrode arrays for peripheral nerve stimulation},
url = {http://dx.doi.org/10.1002/advs.202004033},
volume = {8},
year = {2021}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - There is a critical need to transition research level flexible polymer bioelectronics toward the clinic by demonstrating both reliability in fabrication and stable device performance. Conductive elastomers (CEs) are composites of conductive polymers in elastomeric matrices that provide both flexibility and enhanced electrochemical properties compared to conventional metallic electrodes. This work focuses on the development of nerve cuff devices and the assessment of the device functionality at each development stage, from CE material to fully polymeric electrode arrays. Two device types are fabricated by laser machining of a thick and thin CE sheet variant on an insulative polydimethylsiloxane substrate and lamination into tubing to produce precurled cuffs. Device performance and stability following sterilization and mechanical loading are compared to a stateoftheart stretchable metallic nerve cuff. The CE cuffs are found to be electrically and mechanically stable with improved charge transfer properties compared to the commercial cuff. All devices are applied to an ex vivo whole sciatic nerve and shown to be functional, with the CE cuffs demonstrating superior charge transfer and electrochemical safety in the biological environment.
AU  - Cuttaz,EA
AU  - Chapman,CAR
AU  - Syed,O
AU  - Goding,JA
AU  - Green,RA
DO  - 10.1002/advs.202004033
EP  - 14
PY  - 2021///
SN  - 2198-3844
SP  - 1
TI  - Stretchable, fully polymeric electrode arrays for peripheral nerve stimulation
T2  - Advanced Science
UR  - http://dx.doi.org/10.1002/advs.202004033
UR  - http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000614929100001&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
UR  - https://onlinelibrary.wiley.com/doi/10.1002/advs.202004033
UR  - http://hdl.handle.net/10044/1/86918
VL  - 8
ER  -
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