Publications
83 results found
Clarke AJ, Gulati P, Abraham SM, 2011, A cross-sectional audit of the uptake of seasonal and H1N1 influenza vaccination amongst patients with rheumatoid arthritis in a London hospital., Clin Exp Rheumatol, Vol: 29, ISSN: 0392-856X
Schoenthaler A, Abraham S, Fournier L, et al., 2010, CONTINUITY OF CARE AND MEDICATION ADHERENCE IN HYPERTENSIVE AFRICAN AMERICANS, 33rd Annual Meeting of the Society-of-General-Internal-Medicine, Publisher: SPRINGER, Pages: 248-248, ISSN: 0884-8734
Zhou P, Hatziieremia S, Elliott MA, et al., 2010, Uptake of synthetic low density lipoprotein by leukaemic stem cells - a potential targeted drug delivery strategy, 50th Annual Scientific Meeting of the British-Society-for-Haematology, Publisher: WILEY-BLACKWELL PUBLISHING, INC, Pages: 76-76, ISSN: 0007-1048
Tull TJ, Fisher BA, Jenabzadeh R, et al., 2010, BISPHOSHONATE USE IN ATYPICAL FEMORAL FRACTURES: A CASE -CONTROL STUDY, Annual Meeting of the British-Society-Rheumatology/Spring Meeting of British-Health-Professional-in-Rheumatology, Publisher: OXFORD UNIV PRESS, Pages: I83-I83, ISSN: 1462-0324
Patel L, Abraham S, 2009, <i>Picture Quiz</i> Painful ears and a cough, BMJ-BRITISH MEDICAL JOURNAL, Vol: 339, ISSN: 1756-1833
Cavet G, Shen Y, Abraham S, et al., 2009, Predicting Radiographic Progression in Rheumatoid Arthritis with Ultrasound and Biomarkers, American College Rheumatology
Purpose: The ability to predict progressive joint damage has the potential to improve disease management decisions and outcomes for patients with rheumatoid arthritis (RA). Ultrasonographic B mode imaging (US) can be used to evaluate accumulated joint damage and when used together with power Doppler imaging can also be used for assessment of synovial inflammation and associated vascularity. Studies suggest that expert examination by ultrasound is more sensitive to bone erosions and joint inflammation than X-rays or clinical examination. However, such examination is not available or practical in some clinical settings. Blood-based biomarkers that report on the current rate of joint destructive processes could present a powerful complementary approach to identify patients at risk of accelerated bone and cartilage damage.Method: We examined samples and data from 24 patients followed in a 2-year blinded study comparing methotrexate+infliximab with methotrexate alone in aggressive early RA. Patients were evaluated with US at 0, 18, 54 and 110 weeks and scored for synovial thickening (ST) and for vascularity by power Doppler area (PDA). Radiographic examination with van der Heijde modified Sharp scores was carried out at 0, 30, 54 and 110 weeks. 93 serum proteins associated with biological processes underlying joint damage were measured in serum samples from 0, 6, 18, 54 and 110 weeks. Associations were examined by Spearman correlation. Multivariate analysis used longitudinal hierarchical linear models, evaluated using leave-one-out cross validation.Results: Patients all had erosions at baseline and experienced a wide range of changes in total Sharp scores (TSS; median change 6.25, inter-quartile range 4–14.5). Detailed clinical outcomes are reported elsewhere. Ultrasonographic scores from early in the study were predictive of radiographic progression. Predicted rates of change in TSS from 0–110 weeks based on ST or PDA at 18 weeks (with time and treatment) we
Styles K, Rastogi A, Hussain S, et al., 2009, Influenza vaccination: a cross-sectional prospective audit of influenza vaccination in patients admitted to a London hospital., Clin Med (Lond), Vol: 9, Pages: 506-507, ISSN: 1470-2118
Mangat P, Taylor P, Abraham S, 2009, Comment on: Possible miliary tuberculosis during adalimumab therapy with negative γ-IFN release assays, RHEUMATOLOGY, Vol: 48, Pages: 1177-1178, ISSN: 1462-0324
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Bakshi J, Venables PJ, Abraham S, 2009, Sinonasal sarcoid, JOURNAL OF POSTGRADUATE MEDICINE, Vol: 55, Pages: 43-44, ISSN: 0022-3859
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- Citations: 2
Abraham SM, Taylor PC, 2009, Oxford Handbook of Key Clinical Evidence, Publisher: Oxford University Press, ISBN: 9780199234073
Tull T, Abraham S, 2008, Inflammatory rheumatic conditions and cardiovascular disease, CLINICAL MEDICINE, Vol: 8, Pages: 635-636, ISSN: 1470-2118
Abbott D, Abraham SM, 2008, Takayasu's presenting as fever and cough, Annual Meeting of the British-Society-Rheumatology/Spring Meeting of British Health Professional in Rheumatology, Publisher: OXFORD UNIV PRESS, Pages: II162-II163, ISSN: 1462-0324
Hussain SS, Rastogi A, Kan C, et al., 2008, Uptake of influenza vaccine in general medical patients - Need to improve uptake in the less than 65 year age group and immunosuppressed patients, Annual Meeting of the British-Society-Rheumatology/Spring Meeting of British Health Professional in Rheumatology, Publisher: OXFORD UNIV PRESS, Pages: II119-II119, ISSN: 1462-0324
Abraham SM, Clark AR, 2006, Dual-specificity phosphatase 1: a critical regulator of innate immune responses, BIOCHEMICAL SOCIETY TRANSACTIONS, Vol: 34, Pages: 1018-1023, ISSN: 0300-5127
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- Citations: 119
Abraham SM, Lawrence T, Saklatvala J, et al., 2006, Dual specificity phosphatase-1 (DUSP-1) - A novel mediator of the anti-inflammatory effects of glucocorticoids?, 70th Annual Scientific Meeting of the American-College-of-Rheumatology/41st Annual Scientific Meeting of the Association-of-Rheumatology-Health-Professionals, Publisher: WILEY-LISS, Pages: S513-S513, ISSN: 0004-3591
Abraham S, Mitchell A, Cope A, 2006, Anti-tuberculous therapy-induced crystal arthropathy, Rheumatology, Vol: 45, Pages: 1173-1174
Abraham SM, Lawrence T, Kleiman A, et al., 2006, Antiinflammatory effects of dexamethasone are partly dependent on induction of dual specificity phosphatase 1, JOURNAL OF EXPERIMENTAL MEDICINE, Vol: 203, Pages: 1883-1889, ISSN: 0022-1007
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- Citations: 331
Abraham S, Cope A, 2004, An unusual case of ankle arthropathy, ANNALS OF THE RHEUMATIC DISEASES, Vol: 63, Pages: 460-461, ISSN: 0003-4967
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- Citations: 1
Abraham S, Cope A, Taylor P, 2003, Assessment of rheumatoid arthritis, A Year in Rheumatic Disorders, Editors: Cope, Scott, Oxford, UK, Publisher: Clinical Publishing Services
Lasa M, Abraham SM, Boucheron C, et al., 2002, Dexamethasone causes sustained expression of mitogen-activated protein kinase (MAPK) phosphatase 1 and phosphatase-mediated inhibition of MAPK p38, MOLECULAR AND CELLULAR BIOLOGY, Vol: 22, Pages: 7802-7811, ISSN: 0270-7306
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- Citations: 299
White RP, Abraham S, Singhal S, et al., 2002, Progressive multifocal leucoencephalopathy isolated to the posterior fossa in a patient with systemic lupus erythematosus., Rheumatology (Oxford), Vol: 41, Pages: 826-827, ISSN: 1462-0324
Begum S, Abraham S, Shortall E, et al., 2000, Prevalence of Neuropyschiatric features of SLE using the 1999ACR criteria, Rheumatology, Vol: 39
Hemsley C, Abraham S, Rowland-Jones S, 1999, Corynebacterium pseudodiphtheriticum--a skin pathogen., Clin Infect Dis, Vol: 29, Pages: 938-939
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