Imperial College London

DrSonyaBabu-Narayan

Faculty of MedicineNational Heart & Lung Institute

Reader in Adult Congenital Heart Disease
 
 
 
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Contact

 

+44 (0)20 7351 8803s.babu-narayan

 
 
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Location

 

NIHR Cardiovascular Biomedical RChelsea WingRoyal Brompton Campus

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Summary

 

Publications

Publication Type
Year
to

176 results found

Babu-Narayan SV, Uebing A, Davlouros PA, Kemp M, Davidson S, Dimopoulos K, Bayne S, Pennell DJ, Gibson DG, Flather M, Kilner PJ, Li W, Gatzoulis MAet al., 2012, Randomised trial of ramipril in repaired tetralogy of Fallot and pulmonary regurgitation: the APPROPRIATE study (Ace inhibitors for Potential PRevention Of the deleterious effects of Pulmonary Regurgitation In Adults with repaired TEtralogy of Fallot)., Int J Cardiol, Vol: 154, Pages: 299-305

Optimal treatment for stable repaired tetralogy of Fallot (rTOF) patients with pulmonary regurgitation (PR) and related right ventricular (RV) dilatation, including timing of valve implantation, remains uncertain. We sought to study tolerability of the angiotensin-converting-enzyme (ACE) inhibitor ramipril and its effects on cardiovascular function in these patients.

Journal article

Ernst S, Babu-Narayan SV, Keegan J, Horduna I, Lyne J, Till J, Kilner PJ, Pennell D, Rigby ML, Gatzoulis MAet al., 2012, Remote-Controlled Magnetic Navigation and Ablation With 3D Image Integration as an Alternative Approach in Patients With Intra-Atrial Baffle Anatomy, CIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGY, Vol: 5, Pages: 131-139, ISSN: 1941-3149

Journal article

Teo LLS, Cannell T, Babu-Narayan SV, Hughes M, Mohiaddin RHet al., 2011, Prevalence of Associated Cardiovascular Abnormalities in 500 Patients With Aortic Coarctation Referred for Cardiovascular Magnetic Resonance Imaging to a Tertiary Center, PEDIATRIC CARDIOLOGY, Vol: 32, Pages: 1120-1127, ISSN: 0172-0643

Journal article

Babu-Narayan SV, Gatzoulis MA, 2011, Tetralogy of Fallot, Pages: 316-327

Journal article

Babu-Narayan SV, Mohiaddin RH, Cannell TM, Muhll IV, Dimopoulos K, Mullen MJet al., 2011, Cardiovascular changes after transcatheter endovascular stenting of adult aortic coarctation, INTERNATIONAL JOURNAL OF CARDIOLOGY, Vol: 149, Pages: 157-163, ISSN: 0167-5273

Journal article

El-Hamamsy I, Torii R, Babu-Narayan S, Kilner P, Yacoub MHet al., 2010, LATE AORTIC ROOT BIOMECHANICS FOLLOWING DIFFERENT AORTIC ROOT REPLACEMENT OPERATIONS, CANADIAN JOURNAL OF CARDIOLOGY, Vol: 26, Pages: 118D-118D, ISSN: 0828-282X

Journal article

Beerbaum P, Valverde I, Greil GF, Babu-Narayan SVet al., 2010, Baffles and Conduits, Pages: 316-344

Journal article

Uebing A, Arvanitis P, Li W, Diller GP, Babu-Narayan SV, Okonko D, Koltsida E, Papadopoulos M, Johnson MR, Lupton MG, Yentis SM, Steer PJ, Gatzoulis MAet al., 2010, Effect of pregnancy on clinical status and ventricular function in women with heart disease, INTERNATIONAL JOURNAL OF CARDIOLOGY, Vol: 139, Pages: 50-59, ISSN: 0167-5273

Journal article

Johansson B, Babu-Narayan SV, Kilner PJ, Cannell TM, Mohiaddin RHet al., 2010, 3-dimensional time-resolved contrast-enhanced magnetic resonance angiography for evaluation late after the Mustard operation for transposition, CARDIOLOGY IN THE YOUNG, Vol: 20, Pages: 1-7, ISSN: 1047-9511

Journal article

Johansson B, Babu-Narayan SV, Kilner PJ, Cannell TM, Mohiaddin RHet al., 2010, 3-dimensional time-resolved contrast-enhanced magnetic resonance angiography for evaluation late after the mustard operation for transposition., Cardiol Young, Vol: 20, Pages: 1-7

PURPOSE: Cardiovascular magnetic resonance assessment of adults late after an atrial redirection operation for transposition is demanding and time consuming. We hypothesised that the relatively fast and standardised 3-dimensional time-resolved contrast-enhanced magnetic resonance angiography, or dynamic angiography, would be valuable in the periodic follow-up of these patients. METHODS: We investigated prospectively 36 adults with transposition using dynamic angiography, comparing our results against a comprehensive but non-contrast cardiovascular magnetic resonance protocol. We acquired 6 dynamic angiographic datasets after injection of contrast. The primary aim was to detect significant obstruction of the pathways for venous flow. RESULTS: In 4 patients (11%), we found evidence of moderate-to-severe, and thus clinically important, obstruction of systemic venous channels on standard cardiovascular magnetic resonance. All these patients were correctly identified by dynamic angiography. In 4 additional patients, we found mild and haemodynamically insignificant obstructions in the systemic venous channels. Of the 8 (22%) patients with any obstruction, 6 were detected by angiography. There were no false positives reported, giving sensitivity of 75% and specificity of 100%, a positive predictive value of 100%, and negative predictive value of 93%. In 1 patient, there was a moderate obstruction of the pulmonary venous compartment which was not readily seen by dynamic angiography. CONCLUSIONS: 3-dimensional dynamic angiography is a useful method for detecting anatomically moderate-to-severe, but not mild, obstructions in the systemic venous channels following Mustard repair for transposition. This technique can be used as a single imaging method and/or as complimentary to standard two dimensional cardiovascular magnetic resonance techniques for detection of clinically important obstructions in the systemic venous channels.

Journal article

Perera R, Yadav R, Babu-Narayan S, Mohiaddin R, Pepper Jet al., 2010, Pitfalls of Pectus Repair in Marfan Syndrome: a Case of Successful Re-operation on an Infected Ascending Aortic Graft in a Marfan Patient 20 Years After an Aortic Valve Sparing Root Replacement and Multiple Pectus Repair Operations, Publisher: AMER THORACIC SOC, ISSN: 1073-449X

Conference paper

Babu-Narayan SV, 2010, The role of late gadolinium enhancement cardiovascular magnetic resonance in the assessment of congenital and acquired heart disease, Progress in Pediatric Cardiology, Vol: 28, Pages: 11-19, ISSN: 1058-9813

Cardiovascular magnetic resonance imaging (CMR) has become a cornerstone in the diagnosis and management of congenital heart disease and selected paediatric cardiology patients. This article reviews the relevance of late gadolinium enhancement (LGE) CMR in both congenital and acquired heart diseases. Commonly, adult LGE CMR is with a view to understanding myocardial viability in older ischaemic heart disease patients, where the extent, location, pattern and transmurality of LGE relate to longer term outcomes. However, LGE findings also contribute to diagnosing non-ischaemic cardiomyopathies and their potential aetiology. New uses also include using LGE CMR as an outcome measure in the assessment of interventions including pharmacotherapies. With time there is emerging data regarding a potential role for LGE CMR in risk stratification for arrhythmia and sudden cardiac death. There is therefore understandable interest in its relevance from clinicians involved in assessing and caring for cardiovascular disease in the young, whether congenital or acquired and early reports in these settings are discussed. After outlining aspects concerning principle, practice and pitfalls of the technique, the described clinical experience of late gadolinium enhancement will be discussed. Robust research will be required to fully understand where LGE CMR will fit in with routine clinical paediatric cardiology and adult congenital practice but it seems likely to have a unique role to improve diagnosis and management strategies, determine response to therapies, and assess long term prognosis, not only in ischaemic heart disease patients, but in these cardiac patients too. © 2009 Elsevier Ireland Ltd. All rights reserved.

Journal article

Kilner PJ, Balossino R, Dubini G, Babu-Narayan SV, Taylor AM, Pennati G, Migliavacca Fet al., 2009, Pulmonary regurgitation: The effects of varying pulmonary artery compliance, and of increased resistance proximal or distal to the compliance, INTERNATIONAL JOURNAL OF CARDIOLOGY, Vol: 133, Pages: 157-166, ISSN: 0167-5273

Journal article

Griffin HR, Hall DH, Topf A, Eden J, Stuart AG, Parsons J, Peart I, Deanfield JE, O'Sullivan J, Babu-Narayan SV, Gatzoulis MA, Bu'Lock FA, Bhattacharya S, Bentham J, Farrall M, Riveron JG, Brook JD, Burn J, Cordell HJ, Goodship JA, Keavney Bet al., 2009, Genetic Variation in VEGF Does Not Contribute Significantly to the Risk of Congenital Cardiovascular Malformation, PLOS ONE, Vol: 4, ISSN: 1932-6203

Journal article

Johansson B, Babu-Narayan SV, Kilner PJ, 2009, The effects of breath-holding on pulmonary regurgitation measured by cardiovascular magnetic resonance velocity mapping., J Cardiovasc Magn Reson.

Journal article

Voges I, Fischer G, Scheewe J, Schumacher M, Babu-Narayan SV, Jung O, Kramer H-H, Uebing Aet al., 2008, Restrictive enlargement of the pulmonary annulus at surgical repair of tetralogy of Fallot: 10-year experience with a uniform surgical strategy, EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY, Vol: 34, Pages: 1041-1045, ISSN: 1010-7940

Journal article

Dimopoulos K, Diller G-P, Koltsida E, Pijuan-Domenech A, Papadopoulou SA, Babu-Narayan SV, Salukhe TV, Piepoli MF, Poole-Wilson PA, Best N, Francis DP, Gatzoulis MAet al., 2008, Prevalence, predictors, and prognostic value of renal dysfunction in adults with congenital heart disease, CIRCULATION, Vol: 117, Pages: 2320-2328, ISSN: 0009-7322

Journal article

Uebing A, Babu-Narayan SV, Diller GP, Dimopoulos K, Goktekin O, Spence MS, Andersen K, Gatzoulis MA, Li W, Gibson DG, Henein MYet al., 2008, Response to letter regarding article, "Right Ventricular Mechanics and QRS Duration in Patients With Repaired Tetralogy of Fallot: Implications of Infundibular Disease", CIRCULATION, Vol: 117, Pages: E301-E301, ISSN: 0009-7322

Journal article

Fellowes C, Daly C, Babu-Narayan SV, Lyne J, Collinson Jet al., 2008, Portentous pinball, CANADIAN JOURNAL OF CARDIOLOGY, Vol: 24, Pages: E3-E5, ISSN: 0828-282X

Journal article

Babu-Narayan SV, Uebing A, Kilner PJ, Li W, Gatzouls MAet al., 2007, ACE inhibition improves systolic LV function in patients with pulmonary regurgitation and restrictive RV physiology late after repair of tetralogy of Fallot - A subgroup analysis of the APPROPRIATE study (ACE inhibitors for potential PRevention of the deleterious effects of pulmonary regurgitation in adults with TEtralogy of Fallot repair), 80th Annual Scientific Session of the American-Heart-Association, Publisher: LIPPINCOTT WILLIAMS & WILKINS, Pages: 700-700, ISSN: 0009-7322

Conference paper

Uebing A, Gibson DG, Babu-Narayan SV, Diller GP, Dimopoulos K, Goktekin O, Spence MS, Andersen K, Henein MY, Gatzoulis MA, Li Wet al., 2007, Right ventricular mechanics and QRS duration in patients with repaired tetralogy of Fallot - Implications of infundibular disease, CIRCULATION, Vol: 116, Pages: 1532-1539, ISSN: 0009-7322

Journal article

Johansson B, Maceira MM, Babu-Narayan SV, Moon JC, Pennell DJ, Kilner PJet al., 2007, Clefts can be seen in the basal inferior wall of the left ventricle and the interventricular septum in healthy volunteers as well as patients by cardiovascular magnetic resonance, JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, Vol: 50, Pages: 1294-1295, ISSN: 0735-1097

Journal article

Uebing A, Babu-Narayan SV, Li W, Gatzoulis MAet al., 2007, Cardiovascular magnetic resonance-echocardiography-correlations - Implications of infundibular disease, CLINICAL RESEARCH IN CARDIOLOGY, Vol: 96, Pages: 672-672, ISSN: 1861-0684

Journal article

Bouzas B, Kilner PJ, Pijuan A, Uebing A, Babu-Narayan S, Li W, Gatzoulis MAet al., 2007, Assessment of Ebstein's anomaly by cardiovascular magnetic resonance, EUROPEAN HEART JOURNAL, Vol: 28, Pages: 99-99, ISSN: 0195-668X

Journal article

Goktekin O, Kucukdurmaz Z, Babu-Narayan S, Wong T, Kaya MG, Vatankulu MA, Lam YY, Kilner P, Sutton R, Gatzoulis MAet al., 2007, Microvolt T-wave alternans is related to ventricular tachycardia in adults with repaired tetralogy of fallot, EUROPEAN HEART JOURNAL, Vol: 28, Pages: 151-152, ISSN: 0195-668X

Journal article

Babu-Narayan SV, McCarthy KP, Ho SY, Magee AG, Kilner PJ, Sheppard MNet al., 2007, Myocarditis and sudden cardiac death in the young - Extensive fibrosis suggested by cardiovascular magnetic resonance in vivo and confirmed post mortem, CIRCULATION, Vol: 116, Pages: E122-E125, ISSN: 0009-7322

Journal article

Uebing A, Gibson DG, Babu-Narayan SV, Diller G-P, Golklekin O, Henein MY, Gatzoulis MA, Li Wet al., 2007, Right ventricular mechanics and QRS duration after repair of tetralogy of fallot - Implications of infundibular disease, 56th Annual Scientific Session of the American-College-of-Cardiology, Publisher: ELSEVIER SCIENCE INC, Pages: 271A-271A, ISSN: 0735-1097

Conference paper

Babu-Narayan SV, Gatzoulis MA, Kilner PJ, 2007, Non-invasive imaging in adult congenital heart disease using cardiovascular magnetic resonance, JOURNAL OF CARDIOVASCULAR MEDICINE, Vol: 8, Pages: 23-29, ISSN: 1558-2027

Journal article

Babu-Narayan SV, Kilner PJ, Magee AG, 2006, Heartache in adolescence - non-invasive tissue characterization with cardiovascular magnetic resonance, CARDIOLOGY IN THE YOUNG, Vol: 16, Pages: 604-605, ISSN: 1047-9511

Journal article

Babu-Narayan SV, Li W, Gibson DG, 2006, Assessment of pulmonary regurgitation in adults with surgical repair of tetralogy of Fallot, CARDIOLOGY IN THE YOUNG, Vol: 16, Pages: 606-607, ISSN: 1047-9511

Journal article

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