Imperial College London


Faculty of MedicineNational Heart & Lung Institute

Reader in Adult Congenital Heart Disease



+44 (0)20 7351 8803s.babu-narayan




NIHR Cardiovascular Biomedical RChelsea WingRoyal Brompton Campus






BibTex format

author = {Cazzoli, I and Gunturiz-Beltran, C and Guarguagli, S and Alonso-Gonzalez, R and Babu-Narayan, SV and Dimopoulos, K and Swan, L and Uebing, A and Gatzoulis, MA and Ernst, S},
doi = {10.1016/j.ijcard.2019.09.021},
journal = {International Journal of Cardiology},
pages = {127--134},
title = {Catheter ablation for patients with end-stage complex congenital heart disease or cardiomyopathy considered for transplantation: Trials and tribulations},
url = {},
volume = {301},
year = {2020}

RIS format (EndNote, RefMan)

AB - IntroductionArrhythmia contributes significantly to morbidity and mortality of patients with congenital heart disease (CHD) or cardiomyopathy (CMP). It also has the potential to worsen symptoms and is particularly detrimental to patients with advanced heart failure awaiting cardiac transplantation. We report our experience using catheter ablation to treat recurrent arrhythmia in patients with CHD or CMP considered for transplantation.MethodsFive consecutive patients (3 female, mean age 47.8±12.8years) with complex CHD or CMP (tricuspid atresia, mitral atresia, double inlet left ventricle, arrhythmogenic right ventricular cardiomyopathy, left ventricular non-compaction) presented with either atrial (n=3) or ventricular (n=2) arrhythmias. All ablations were guided by three-dimensional (3D) electro-anatomical mapping, plus remote magnetic navigation in 3 patients.ResultsPatients underwent a median of 2 ablation procedures for a total number of 26 tachycardias. None of the 5 patients experienced further arrhythmia at a median of 939days (range 4–1375) from their last ablation. During a median follow up of 31months (range 1–70), three patients underwent successful transplantation at 1375, 1062 and 321days following their last ablation. One patient with a Fontan circulation died from hepatic cancer and one from end-stage heart failure despite urgent transplant listing.ConclusionsCatheter ablation is feasible in complex cardiac patients considered for heart transplantation and should be offered for rhythm management and patient optimization until a suitable donor is found.
AU - Cazzoli,I
AU - Gunturiz-Beltran,C
AU - Guarguagli,S
AU - Alonso-Gonzalez,R
AU - Babu-Narayan,SV
AU - Dimopoulos,K
AU - Swan,L
AU - Uebing,A
AU - Gatzoulis,MA
AU - Ernst,S
DO - 10.1016/j.ijcard.2019.09.021
EP - 134
PY - 2020///
SN - 0167-5273
SP - 127
TI - Catheter ablation for patients with end-stage complex congenital heart disease or cardiomyopathy considered for transplantation: Trials and tribulations
T2 - International Journal of Cardiology
UR -
UR -
UR -
VL - 301
ER -