Imperial College London

DrSonyaBabu-Narayan

Faculty of MedicineNational Heart & Lung Institute

Reader in Adult Congenital Heart Disease
 
 
 
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Contact

 

+44 (0)20 7351 8803s.babu-narayan

 
 
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Location

 

NIHR Cardiovascular Biomedical RChelsea WingRoyal Brompton Campus

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Summary

 

Publications

Publication Type
Year
to

217 results found

Heng EL, Kellman P, Gatzoulis MA, Moon J, Gatehouse P, Babu-Narayan SVet al., 2015, Pilot data of right ventricular myocardial T1 quantification by free-breathing fat-water separated dark blood saturation-recovery imaging, Journal of Cardiovascular Magnetic Resonance, Pages: 1-2, ISSN: 1097-6647

Journal article

Heng EL, Kellman P, Mohiaddin R, Alpendurada F, Kilner PJ, Pennell DJ, Gatzoulis MA, Keegan J, Babu-Narayan SVet al., 2015, The utility of free-breathing, motion-corrected late gadolinium enhancement for right ventricular fibrosis imaging in congenital heart disease, Journal of Cardiovascular Magnetic Resonance, Pages: 1-2, ISSN: 1097-6647

Journal article

Rydman R, Shiina Y, Gatzoulis MA, Pennell DJ, Kilner PJ, Babu-Narayan SVet al., 2015, Predicting atrial tachycardia and major cardiovascular events in adults with unrepaired Ebstein's anomaly of the tricuspid valve, Journal of Cardiovascular Magnetic Resonance, Pages: 1-2, ISSN: 1097-6647

Journal article

Moceri P, Kempny A, Liodakis E, Gonzales RA, Germanakis I, Diller G-P, Swana L, Marino PS, Wort SJ, Babu-Narayan SV, Ferrari E, Gatzoulis MA, Li W, Dimopoulos Ket al., 2015, Physiological differences between various types of Eisenmenger syndrome and relation to outcome, INTERNATIONAL JOURNAL OF CARDIOLOGY, Vol: 179, Pages: 455-460, ISSN: 0167-5273

Journal article

Keegan J, Gatehouse PD, Haldar S, Wage R, Babu-Narayan SV, Firmin DNet al., 2015, Dynamic Inversion Time for Improved 3D Late Gadolinium Enhancement Imaging in Patients with Atrial Fibrillation, Magnetic Resonance in Medicine, Vol: 73, Pages: 646-654, ISSN: 1522-2594

Purpose—High resolution 3D late gadolinium enhancement (LGE) imaging is performed withsingle R-wave gating to minimise lengthy acquisition durations. In patients with atrial fibrillation(AF), heart rate variability results in variable magnetisation recovery between sequence repeatsand image quality is often poor. In this study, we implemented and tested a dynamic inversiontime scheme designed to reduce sequence sensitivity to heart rate variations.Methods—An inversion-prepared 3D segmented gradient echo sequence was modified so thatthe inversion time (TI) varied automatically from beat-to-beat (dynamic-TI) based on the timesince the last sequence repeat. 3D LGE acquisitions were performed in 17 patients prior to RFablation of persistent AF both with and without dynamic-TI. Qualitative image quality scores,blood signal-to-ghosting ratios (SGRs) and blood-myocardium contrast-to-ghosting ratios (CGRs)were compared.Results—Image quality scores were higher with dynamic-TI than without (2.2 +/− 0.9 versus 1.8+/− 1.1, p = 0.008) as were blood-myocardium CGRs (13.8 +/− 7.6 versus 8.3 +/− 6.1, p = 0.003)and blood SGRs (19.6 +/− 8.5 versus 13.1 +/− 8.0, p = 0.003).Conclusions—The dynamic-TI algorithm improves image quality of 3D LGE imaging in thisdifficult patient population by reducing the sequence sensitivity to RR interval variations.

Journal article

Pennell DJ, Baksi AJ, Kilner PJ, Mohiaddin RH, Prasad SK, Alpendurada F, Babu-Narayan SV, Neubauer S, Firmin DNet al., 2014, Review of Journal of Cardiovascular Magnetic Resonance 2013, Journal of Cardiovascular Magnetic Resonance, Vol: 16, ISSN: 1532-429X

There were 109 articles published in the Journal of Cardiovascular Magnetic Resonance (JCMR) in 2013, which is a21% increase on the 90 articles published in 2012. The quality of the submissions continues to increase. The editorsare delighted to report that the 2012 JCMR Impact Factor (which is published in June 2013) has risen to 5.11, upfrom 4.44 for 2011 (as published in June 2012), a 15% increase and taking us through the 5 threshold for the firsttime. The 2012 impact factor means that the JCMR papers that were published in 2010 and 2011 were cited onaverage 5.11 times in 2012. The impact factor undergoes natural variation according to citation rates of papers inthe 2 years following publication, and is significantly influenced by highly cited papers such as official reports.However, the progress of the journal's impact over the last 5 years has been impressive. Our acceptance rate is<25% and has been falling because the number of articles being submitted has been increasing. In accordancewith Open-Access publishing, the JCMR articles go on-line as they are accepted with no collating of the articlesinto sections or special thematic issues. For this reason, the Editors have felt that it is useful once per calendaryear to summarize the papers for the readership into broad areas of interest or theme, so that areas of interestcan be reviewed in a single article in relation to each other and other recent JCMR articles. The papers arepresented in broad themes and set in context with related literature and previously published JCMR papers toguide continuity of thought in the journal. We hope that you find the open-access system increases widerreading and citation of your papers, and that you will continue to send your quality manuscripts to JCMR forpublication.

Journal article

Cambronero Cortinas E, Garcia Guereta Silva L, Rivero Jimenez N, Deiros Bronte L, Bret Zurita M, Sanz Pascual E, Labrandero C, Corbi Pascual M, Arreo Del Val V, Gutierrez Laraya Aguado F, Shimada E, West C, Babu-Narayan S, Li W, Castro M, Abecasis J, Santos M, Reis C, Ribeiras R, Marques M, Andrade M, Abecasis M, Mendes M, Karvounaris S, Karampetsos V, Michas G, Argirou A, Mavrommatis P, Pereira VH, Portugues J, Calvo L, Ferreira F, Machado I, Lourenco M, Lourenco A, Bercu G, Tamisier Det al., 2014, Case-based session: new ways to look at old problems in cardiac heart disease: Saturday 6 December 2014, 11:00-12:30Location: Agora., Eur Heart J Cardiovasc Imaging, Vol: 15 Suppl 2, Pages: ii230-ii231

Journal article

Heng EL, Babu-Narayan SV, 2014, Repaired tetralogy of fallot, Cardiac CT and MR for Adult Congenital Heart Disease, Pages: 199-224, ISBN: 9781461488743

The anatomy of tetralogy of Fallot (TOF), together with the pathophysiological consequences, was first described by Etienne-Louis Fallot in 1888. The tetrad of overriding aorta, right ventricular (RV) outflow tract obstruction, ventricular septal defect (VSD) and consequent RV hypertrophy is all due to antero-cephalad deviation of the outlet septum during fetal development. TOF is the most common cyanotic congenital heart disease (CHD), accounting for 10 % of CHD patients and occurring in 1 in 3,600 births (Shinebourne et al., Heart 92:1353-1359, 2006). It carries a recurrence risk of 3 % in siblings. There is genetic microdeletion in 22q11 in 15-25 % of TOF patients in whom TOF is part of DiGeorge syndrome. There is a spectrum of morphology, despite the four features that comprise 'tetralogy', and the severity of the RV outflow tract (RVOT) obstruction is the major determinant of first clinical presentation. Surgical palliation was achieved using the Blalock-Taussig shunt (subclavian artery to ipsilateral pulmonary artery connection) in 1944, a landmark event as these patients underwent the first cardiac surgery. Subsequently, surgical repair was described in the 1950s with the advent of cardiopulmonary bypass. Primary surgical repair involves patch closure of the VSD and intervention to the RVOT to relieve obstruction. RV muscle bundles are resected. Depending on the size of the outflow tract, pulmonary valve and pulmonary arteries; an RVOT patch, transannular patch and/or pulmonary artery (PA) patch may be required for RVOT reconstruction. In the variants with anomalous coronary arteries or in pulmonary atresia-type Fallot, an RV to PA conduit may be used.

Book chapter

Kempny A, Diller GP, Dimopoulos K, Alonso-Gonzalez R, Uebing A, Li W, Babu-Narayan S, Swan L, Wort SJ, Gatzoulis MAet al., 2014, Attendance of outpatient clinic appointments amongst adults with congenital heart disease: predictors and relation to outcome, Annual Meeting of the European-Society-of-Cardiology (ESC), Publisher: OXFORD UNIV PRESS, Pages: 517-518, ISSN: 0195-668X

Conference paper

Menichetti F, Spadotto V, Zorzi A, Kempny A, Horduna IS, Mantziari L, Leventopoulos G, Babu-Narayan S, Ernst Set al., 2014, Predictors of supraventricular arrhythmias (SA) and outcome of catheter ablation in patients with ebstein anomaly (EA): a single-center experience, Annual Meeting of the European-Society-of-Cardiology (ESC), Publisher: OXFORD UNIV PRESS, Pages: 584-584, ISSN: 0195-668X

Conference paper

Heng EL, Bolger AP, Kempny A, Davlouros P, Davidson S, Gatzoulis MA, Babu-Narayan SVet al., 2014, SERUM BNP AND CLINICAL OUTCOMES PREDICTION IN TETRALOGY OF FALLOT: A PROSPECTIVE ANALYSIS, HEART, Vol: 100, Pages: A25-A26, ISSN: 1355-6037

Journal article

Broberg CS, Prasad SK, Carr C, Babu-Narayan SV, Dimopoulos K, Gatzoulis MAet al., 2014, Myocardial fibrosis in Eisenmenger syndrome: a descriptive cohort study exploring associations of late gadolinium enhancement with clinical status and survival, JOURNAL OF CARDIOVASCULAR MAGNETIC RESONANCE, Vol: 16, ISSN: 1097-6647

Journal article

Ben-Haim S, Menichetti F, Roth N, Baavour R, Bomanji J, Babu-Narayan S, Underwood S, Ernst Set al., 2014, Localization of ganglionated plexi in patients with cardiac arrhythmia - A new application for 123I-mIBG SPECT, Annual Meeting of the Society-of-Nuclear-Medicine-and-Molecular-Imaging (SNMMI), Publisher: SOC NUCLEAR MEDICINE INC, ISSN: 0161-5505

Conference paper

Shiina Y, Babu-Narayan S, Niwa K, Rydman R, Li W, Karonis T, Papaioannou V, Tutarel O, Kempny A, Diller G-P, Kilner P, Uemura H, Gatzoulis Met al., 2014, LEFT VENTRICULAR DYSFUNCTION HAS AN ADITIONAL NEGATIVE IMPACT ON CARDIAC OUTCOMES IN ADULTS WITH EBSTEIN'S ANOMALY, JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, Vol: 63, Pages: A567-A567, ISSN: 0735-1097

Journal article

Shah BN, Babu-Narayan S, Li W, Rubens M, Wong Tet al., 2014, Severe Mitral Annular Calcification: Insights from Multimodality Imaging, TEXAS HEART INSTITUTE JOURNAL, Vol: 41, Pages: 245-247, ISSN: 0730-2347

Journal article

Curry RA, Gelson E, Swan L, Dob D, Babu-Narayan SV, Gatzoulis MA, Steer PJ, Johnson MRet al., 2014, Marfan syndrome and pregnancy: maternal and neonatal outcomes, BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, Vol: 121, Pages: 610-617, ISSN: 1470-0328

Journal article

Keegan J, Jhooti P, Babu-Narayan SV, Drivas P, Ernst S, Firmin DNet al., 2014, Improved Respiratory Efficiency of 3D Late Gadolinium Enhancement Imaging Using the Continuously Adaptive Windowing Strategy (CLAWS), MAGNETIC RESONANCE IN MEDICINE, Vol: 71, Pages: 1064-1074, ISSN: 0740-3194

Journal article

Valente AM, Gauvreau K, Assenza GE, Babu-Narayan SV, Schreier J, Gatzoulis MA, Groenink M, Inuzuka R, Kilner PJ, Koyak Z, Landzberg MJ, Mulder B, Powell AJ, Wald R, Geva Tet al., 2014, Contemporary predictors of death and sustained ventricular tachycardia in patients with repaired tetralogy of Fallot enrolled in the INDICATOR cohort, HEART, Vol: 100, Pages: 247-253, ISSN: 1355-6037

Journal article

Babu-Narayan SV, Diller G-P, Gheta RR, Bastin AJ, Karonis T, Li W, Pennell DJ, Uemura H, Sethia B, Gatzoulis MA, Shore DFet al., 2014, Clinical Outcomes of Surgical Pulmonary Valve Replacement After Repair of Tetralogy of Fallot and Potential Prognostic Value of Preoperative Cardiopulmonary Exercise Testing, CIRCULATION, Vol: 129, Pages: 18-27, ISSN: 0009-7322

Journal article

Shiina Y, Niwa K, Li W, Rydman R, Uemura H, Pennell D, Kilner P, Gatzoulis MA, Babu-Narayan Set al., 2013, Non-invasive Predictors of Cardiac Outcomes in Adults With Ebstein Anomaly, Scientific Sessions and Resuscitation Science Symposium of the American-Heart-Association, Publisher: LIPPINCOTT WILLIAMS & WILKINS, ISSN: 0009-7322

Conference paper

Bradlow WM, Babu-Narayan SV, Mohiaddin RH, 2013, Pulmonary hypertension in congenital heart disease, Cardiac CT and MR for Adult Congenital Heart Disease, Pages: 553-572, ISBN: 9781461488743

The occurrence of pulmonary hypertension (PH) in patients with congenital heart disease (CHD) is not uncommon and represents an important complication. This chapter sets out the scale of the problem before describing where cross-sectional imaging is used in diagnosis. Prognostication and assessment of therapeutic effect using these techniques is then explored before examining Eisenmenger's syndrome in detail. A discussion on related abnormalities of the pulmonary arteries is included.

Book chapter

Vieira MS, Alpendurada F, Babu-Narayan S, Kilner Pet al., 2013, Criss-cross heart: Twisted anatomy by cardiovascular magnetic resonance, REVISTA PORTUGUESA DE CARDIOLOGIA, Vol: 32, Pages: 947-949, ISSN: 0870-2551

Journal article

Bonello B, Kempny A, Uebing A, Li W, Kilner PJ, Diller G-P, Pennell DJ, Shore DF, Ernst S, Gatzoulis MA, Babu-Narayan SVet al., 2013, Right atrial area and right ventricular outflow tract akinetic length predict sustained tachyarrhythmia in repaired tetralogy of Fallot, INTERNATIONAL JOURNAL OF CARDIOLOGY, Vol: 168, Pages: 3280-3286, ISSN: 0167-5273

Journal article

Shiina Y, Li W, Bouzas B, Rydman R, Kempny A, Karonis T, Tutarel O, Gatzoulis MA, Kilner PJ, Babu-Narayan SVet al., 2013, Cardiac index, left ventricular longitudinal systolic function and atrialised right ventricle size affect exercise capacity in adults with Ebsteins anomaly, Congress of the European-Society-of-Cardiology (ESC), Publisher: OXFORD UNIV PRESS, Pages: 17-17, ISSN: 0195-668X

Conference paper

Mantziari L, Ueda A, Suman-Horduna I, Ho SY, Babu-Narayan S, Ernst Set al., 2013, Radiofrequency ablation of supraventricular tachycardias in patients with congenital heart disease and difficult access to the chamber of interest using remote magnetic navigation, Congress of the European-Society-of-Cardiology (ESC), Publisher: OXFORD UNIV PRESS, Pages: 902-902, ISSN: 0195-668X

Conference paper

Ernst S, Pedersen M, Uebing A, Suman-Horduna I, Mantziari L, Li W, Babu-Narayan SVet al., 2013, Successful ablation of two right atrial tachycardias on either side of the lateral tunnel patch in a patient with double inlet left ventricle and total cavopulmonary connection: Two sites and two mechanisms., Global Cardiology Science and Practice, Vol: 2013, Pages: 198-202, ISSN: 2305-7823

Journal article

Mantziari L, Suman-Horduna I, Babu-Narayan SV, Ernst Set al., 2013, Advanced ablation strategies for management of post-surgical atrial arrhythmias., Gobal Cardiology Science and Practice, Vol: 2013, Pages: 140-148, ISSN: 2305-7823

Post-surgical arrhythmias include a wide range of arrhythmias occurring late after cardiac surgery and represent a complex substrate for catheter ablation either because of extended scar and remodeling or because of limited access to the area of interest. Novel image integration and ablation tools have made the catheter ablation in this population both feasible and successful. We review a structured approach to catheter ablation of post-surgical atrial arrhythmias in various patient cohorts including the most common congenital heart defects.

Journal article

Mantziari L, Babu-Narayan SV, Suman-Horduna I, Rigby ML, Ernst Set al., 2013, Atrial arrhythmia after Fontan surgery leads to giant thrombus: Opening Pandora's box, INTERNATIONAL JOURNAL OF CARDIOLOGY, Vol: 166, Pages: E23-E24, ISSN: 0167-5273

Journal article

Suman-Horduna I, Babu-Narayan SV, Ueda A, Mantziari L, Gujic M, Marchese P, Dimopoulos K, Gatzoulis MA, Rigby ML, Ho SY, Ernst Set al., 2013, Magnetic navigation in adults with atrial isomerism (heterotaxy syndrome) and supraventricular arrhythmias, EUROPACE, Vol: 15, Pages: 877-885, ISSN: 1099-5129

Journal article

Ueda A, Suman-Horduna I, Mantziari L, Gujic M, Marchese P, Ho SY, Babu-Narayan SV, Ernst Set al., 2013, Contemporary Outcomes of Supraventricular Tachycardia Ablation in Congenital Heart Disease: A Single-Center Experience in 116 Patients, CIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGY, Vol: 6, Pages: 606-613, ISSN: 1941-3149

Journal article

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